Externally used pharmaceutical composition for ophthalmic operation pre-operative prevention

Abstract

The invention discloses an externally used pharmaceutical composition for ophthalmic operation pre-operative prevention. The pharmaceutical composition is prepared from the following bulk drugs by weight: 10-30 parts of Bambusa multiplex, 15-25 parts of Zizania caduciflora, 6-10 parts of loofah sponge, 3-10 parts of Brassica alboglabra, 6-12 parts of Medicago hispida, 3-10 parts of Rhizoma Cimicifugae, 2-5 parts of Daphniphyllum calycinum, 5-15 parts of bark of ligustrum lucidum, 60-120 parts of root of oryza sativa L., 5-15 parts of rhizoma anemones altaicae, and 1-3 parts of Ilex cornuta. The agent provided by the invention has reasonable formula and clear curative effect, and can effectively reduce the incidence of undesirable wound healing in diabetic patient ophthalmic operation.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to an external pharmaceutical composition for ophthalmic surgery preoperative prevention. Background technique [0002] The eye is one of the most vulnerable target organs in diabetic patients, which can cause various eye complications such as cataract, external ophthalmoplegia, etc. According to reports, the average prevalence of retinopathy caused by diabetes is 50% to 63%. More than 50% of cataract patients are diabetic. [0003] Before ophthalmic surgery, the blood sugar control requirements for diabetic patients are the most stringent. For general surgery, preoperative blood sugar control requires fasting blood sugar to <10.0mmol / L, while eye surgery requires fasting blood sugar to <8.3mmol / L ( "Ophthalmology"), even <6.7mmol / L ("Handbook of Ophthalmology"). The reasons are: the repair ability of local tissues in diabetic patients is reduced; and the incre...

AI Technical Summary

Problems solved by technology

The reasons are: the repair ability of local tissues in diabetic patients is reduced; and the increase of blood sugar causes protein synthesis to decrease, decomposition to increase, cell metabolism to be abnormal, fibroblast function at the wound to decrease, epithelial hyperplasia to reduce collagen deposition, and the tensile strength of the wound to decrease. Insufficient, when the wound heals, there is a lack of a growth factor from platelets, resulting in delayed or non-healed wound healing; high blood sugar weakens the bactericidal ability of white blood cells; antibacterial substances in the body (such as antibodies, complements, etc.) The hypoxia caused by the lesion creates an environment conducive to the reproduction of bacteria, and other reasons lead to complications of surgical incisions in diabetic patients, such as persistent bloody secretions and even delayed healing

In addition, the healing of diabetic patients after eye surgery is difficult, and it is difficult to deal with it. There are few preoperative intervention programs.