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Preparation method of preoperative medicine for patients with diabetics

A technology for diabetes and patients, applied in the field of preparation of preoperative drugs for diabetic patients, can solve the problems of insufficient wound tensile strength, weakened leukocyte bactericidal power, poor healing, etc. The effect of transdermal absorption

Inactive Publication Date: 2016-10-12
孙艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The main feature of diabetes is elevated blood sugar, which is a metabolic disease, and the main complications are microvascular disease and macrovascular disease. Since most diabetic patients have a long course of disease, high nutritional consumption, and low immunity, the accompanying vascular disease makes nutrition difficult. The material supply is obstructed, and the repair ability of local tissues is reduced; while the increase in blood sugar causes protein synthesis to decrease, decomposition to increase, cell metabolism to be abnormal, fibroblast function at the wound to decrease, epithelial hyperplasia to reduce collagen deposition, and the tensile strength of the wound to be insufficient , when the wound heals, the lack of a growth factor from platelets leads to delayed or non-healed wound healing; high blood sugar weakens the bactericidal ability of white blood cells; antibacterial substances in the body (such as antibodies, complements, etc.) decrease, coupled with vascular disease The resulting hypoxia creates an environment conducive to the reproduction of bacteria, and other reasons lead to complications of surgical incisions in diabetic patients, such as persistent bloody secretions and even delayed healing
[0003] Diabetic patients have poor healing after orthopedic surgery, and it is difficult to heal with general surgical dressing changes, and there are few preoperative intervention programs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1, the weight ratio of raw materials is: sea earthworm 20g, mozuku 20g, leopard skin mushroom 10g, jiuxiancao 10g, bean hemp 8g, pineapple peel 6g, rock spring grass 8g, wood hoof 7g, sage 10g, dwarf sage Gooseberry 3g, Dancing grass 1g, Eurya 2g.

[0031] The preparation method of embodiment 1 is: sea earthworm, leopard skin mushroom, Jiuxian grass, bean hemp, pineapple skin, rock spring grass, wood hoof, sage grass, dwarf currant, dancing grass, eurya microtrichum, mozuku, Wash and remove impurities, and put them in a decoction casserole. Add cold water over the medicinal surface, soak for 60 minutes, decoct with strong fire until boiling, then change to simmer for 30 minutes, decoct twice in total, filter with gauze and combine the decoction, and take it orally twice.

Embodiment 2

[0032] Example 2, the weight ratio of raw materials is: 10 parts of sea earthworm, 25 parts of mozuku, 5 parts of leopard skin mushroom, 15 parts of Jiuxiancao, 6 parts of bean hemp, 3 parts of pineapple peel, 12 parts of rock spring grass, 10 parts of wood hoof , 6 parts of sage, 2 parts of dwarf currant, 3 parts of dancing grass, and 1 part of eurya.

Embodiment 3

[0033] Example 3, the weight ratio of raw materials is: 20 parts of sea earthworm, 20 parts of mozuku, 10 parts of leopard skin mushroom, 10 parts of Jiuxiancao, 8 parts of bean hemp, 6 parts of pineapple peel, 8 parts of rock spring grass, 7 parts of wood hoof , 10 parts of Sage, 3 parts of Dwarf Currant, 1 part of Dancing Grass, and 2 parts of Eustoma.

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PUM

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Abstract

The invention discloses a preparation method of a preoperative medicine for patients with diabetics. The preparation method comprises the following steps: (1) cleaning the following materials: arenicola cristata, cladosiphon okamuranus, lentinus lepideus fr, longleaf bastardtoadflax herb, laportea violacea gaghep, pineapple peels, moellendorf's spidemoss herb, pyropolyporus formentarius teng, herb of elsholtzia rugulosa hemsl, swamp currant, codariocalyx motorius and eurya hebeclados, removing impurities, airing and crushing the materials, so that particles are prepared; (2) mixing the particulate medicinal materials obtained in the step (1), soaking the materials in water, decocting the materials twice, combining two times of decoctions, and conducting filtering and concentrating; and (3) storing a concentrated solution obtained in the step obtained in the step (2) at low temperature, adding diatomite which serves as a filter aid, conducting filtering, and refrigerating an obtained filtrate at 0-5 DEG C for 24h, so that oral liquid is obtained. The medicine disclosed by the invention is reasonable in prescription, concrete in curative effect, and the medicine is capable of effectively preventing un-healed wounds in patients with diabetics in the orthopedic surgery.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a method for preparing preoperative medicine for diabetic patients. Background technique [0002] The main feature of diabetes is elevated blood sugar, which is a metabolic disease. The main complications are microvascular disease and macrovascular disease. Since most diabetic patients have a long course of disease, large nutrient consumption, and low immunity, the accompanying vascular disease makes nutrition difficult. The material supply is obstructed, and the repair ability of local tissues is reduced; while the increase of blood sugar causes protein synthesis to decrease, decomposition to increase, cell metabolism to be abnormal, fibroblast function at the wound to decrease, epithelial hyperplasia to reduce collagen deposition, and wound tensile strength to be insufficient , when the wound heals, the lack of a growth factor from platelets leads to delayed or non-h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P3/10A61P17/02A61K35/62
CPCA61K36/88A61K9/0095A61K35/62A61K36/02A61K36/06A61K36/07A61K36/11A61K36/185A61K36/48A61K36/53A61K36/82A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 孙艳马祖强
Owner 孙艳
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