Unlock instant, AI-driven research and patent intelligence for your innovation.

A kind of method for producing water-insoluble organic acid by bipolar membrane electrodialysis

A bipolar membrane electrodialysis, non-water-soluble technology, applied in electrodialysis, preparation of organic compounds, organic chemistry, etc., can solve the problems of poor conductivity of organic solvents, high energy consumption, large resistance of membrane stacks, etc., to save chemical industry Raw materials, the effect of achieving cleaner production, significant industrial application value and environmental benefits

Active Publication Date: 2019-01-22
UNIV OF SCI & TECH OF CHINA
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the application of bipolar membrane electrodialysis to organic acids with poor water solubility, there are some reports at present, such as the Journal of Membrane Science magazine 2015 482 pages 76-82, which discloses the document Bipolar membrane electrodialysis in aqua-ethanol medium: Production of salicylic acid ( Bipolar membrane electrodialysis produces salicylic acid in a water-ethanol system), and the solubility of salicylic acid is increased by using a water-ethanol mixed system, but due to the poor conductivity of organic solvents, the resistance of the membrane stack is large and the energy consumption is high
At the same time, this method is not suitable for organic acids such as phenylglycine, which are insoluble in water and general organic solvents.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of method for producing water-insoluble organic acid by bipolar membrane electrodialysis
  • A kind of method for producing water-insoluble organic acid by bipolar membrane electrodialysis
  • A kind of method for producing water-insoluble organic acid by bipolar membrane electrodialysis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] First, put 400mL of 0.3mol / L sodium sulfate solution into the electrode solution storage tank as the electrode solution. Initially put 400mL of 0.05mol / L sodium hydroxide into the alkali storage tank to reduce the initial resistance. Keep a sufficient amount of 0.3mol / L sodium sulfate solution in the sodium sulfate storage tank of the feed solution, pass it into the two-compartment bipolar membrane electrodialysis membrane stack through a peristaltic pump, and then directly flow out into the acid storage tank. At the same time, the acid in the acid storage tank is passed into the 100mL 2mol / L sodium phenylglycinate solution to be treated at the same flow rate as the acid chamber through the peristaltic pump. Before turning on the power, turn on the peristaltic pump to circulate the whole device for half an hour to eliminate the damage of air bubbles to the membrane. After the power is turned on, use a stopwatch to count the time, and record the voltage value of the pow...

Embodiment 2

[0041] First, put 400mL of 0.3mol / L sodium sulfate solution into the electrode solution storage tank as the electrode solution. Initially put 400mL of 0.05mol / L sodium hydroxide into the alkali storage tank to reduce the initial resistance. Keep a sufficient amount of 0.3mol / L sodium sulfate solution in the sodium sulfate storage tank of the feed solution, pass it into the two-compartment bipolar membrane electrodialysis membrane stack through a peristaltic pump, and then directly flow out into the acid storage tank. At the same time, the acid in the acid storage tank is passed into the 100mL 2mol / L sodium phenylglycinate solution to be treated at the same flow rate as the acid chamber through the peristaltic pump. Before turning on the power, turn on the peristaltic pump to circulate the whole device for half an hour to eliminate the damage of air bubbles to the membrane. After the power is turned on, use a stopwatch to count the time, and record the voltage value of the pow...

Embodiment 3

[0043] First, put 400mL of 0.3mol / L sodium sulfate solution into the electrode solution storage tank as the electrode solution. Initially put 400mL of 0.05mol / L sodium hydroxide into the alkali storage tank to reduce the initial resistance. Keep a sufficient amount of 0.3mol / L sodium sulfate solution in the sodium sulfate storage tank of the feed solution, pass it into the two-compartment bipolar membrane electrodialysis membrane stack through a peristaltic pump, and then directly flow out into the acid storage tank. At the same time, the acid in the acid storage tank is passed into the 100mL 2mol / L sodium phenylglycinate solution to be treated at the same flow rate as the acid chamber through the peristaltic pump. Before turning on the power, turn on the peristaltic pump to circulate the whole device for half an hour to eliminate the damage of air bubbles to the membrane. After the power is turned on, use a stopwatch to count the time, and record the voltage value of the pow...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a method for producing water-insoluble organic acid by bipolar membrane electrodialysis. The method comprises the steps that a sodium sulfate aqueous solution is pumped into a bipolar membrane electrodialysis device to produce sulfuric acid and sodium hydroxide, the produced sulfuric acid is used for acidifying water-insoluble organic acid sodium salt to produce the water-insoluble organic acid and sodium sulfate, the produced water-insoluble organic acid solid is filtered and collected to obtain the required product, and the sodium sulfate aqueous solution used as a filtrate is used as a feed liquid to form a closed production loop. By the adoption of the method for producing the water-insoluble organic acid by the bipolar membrane electrodialysis, the full-closed and cycled clean production of the water-insoluble organic acid such as phenylglycine can be realized, so that chemical materials can be saved and a large number of high salinity wastewater can be avoided, the environmental pollution is reduced, and industrial application values and environmental benefits are obvious.

Description

technical field [0001] The invention relates to a method for producing water-insoluble organic acid by bipolar membrane electrodialysis. technical background [0002] Amino acid is an important organic compound. It is the basic substance that constitutes the protein required for animal nutrition. It is widely used in many industries such as medicine, food, chemical industry, agriculture, and environmental protection. Among them, phenylglycine, which is a fine chemical product, has developed rapidly in recent years. It is widely used as an important side chain intermediate for the preparation of ampicillin, cephalexin and its derivatives of β-lactam antibiotics. [0003] The synthesis and preparation methods of phenylglycine include phenylhydantoin method, glyoxylic acid method, phenylacetic acid method, biological enzyme method, chloroform method and phase transfer catalysis method, etc. At present, dihydantoin method is widely used because of its simple principle, mature t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): B01D61/48B01D61/52C07C229/36C07C227/18C07C65/10C07C51/41
CPCB01D61/48B01D61/52C07C51/412C07C227/18C07C229/36C07C65/10
Inventor 徐铜文周永明汪耀明
Owner UNIV OF SCI & TECH OF CHINA