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Traditional Chinese medicine for treating liver-qi stagnation type breast cancer and preparation method thereof

A technology for stagnation of liver qi and breast cancer, applied in medical formulas, medical preparations containing active ingredients, anti-tumor drugs, etc., can solve the problems of cardiovascular system toxicity, heart failure, and affecting fertility, etc., to eliminate adverse effects Effects that react, prolong survival time, provide healing effects

Inactive Publication Date: 2016-10-12
姜永华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] 4. Some chemotherapeutic drugs have toxic effects on the cardiovascular system, and heart failure may occur in severe cases
[0015] 5. Chemotherapy drugs that have toxic effects and adverse reactions on the respiratory system can cause acute chemical pneumonia and chronic pulmonary fibrosis, and even respiratory failure
[0017] 7. Some drugs can affect fertility and cause teratogenicity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0054] When the dosage form of any one of the above-mentioned Chinese medicines is a granule, its preparation method comprises the following steps:

[0055] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , using the filter residue as the solute, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, and then concentrate it under reduced pressure at a vacuum of 0.06-0.09Mpa to 50-60°C with a relative density of 1.04 ~1.10 paste, spray drying, the air inlet temperature of the spray dryer is 160~175℃, and the air outlet temperature is 80~85℃, and then crushed into powder to make dry paste powder;

[0056] Step 2: Add 0.2-0.4 times of sucrose powder and 0.1-0.2 times of dextrin to the obtained dry cream powder to form gr...

Embodiment 1

[0062] Embodiment 1: Granules

[0063] Take Hetao rhubarb 160g, golden hair grass 210g, creeping dragon 240g, dragon fruit 180g, clam powder 140g, wild amaranth 300g, Junqianzi 180g, duckbill huang 190g, pamao fruit 200g, chicken dung tree 160g, red thorn vine 280g , Libai 210g, Chafengtong 250g and Shimoda chrysanthemum 160g;

[0064] Its preparation method comprises the following steps:

[0065] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 90% which is 5 times that of the mixture, heat to boiling and reflux for 4 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute, using The percolation method slowly percolates at a rate of 1ml per minute, collects the percolation liquid, and then concentrates it under reduced pressure at a vacuum of 0.07Mpa to a paste with a relative density of 1.05 at 55°C, sprays and dries, and the air inlet of the spray dryer The temperature...

Embodiment 2

[0067] Embodiment 2: tablet

[0068]Take Hetao rhubarb 180g, golden hair grass 190g, creeping dragon 260g, dragon fruit 220g, clam powder 120g, wild amaranth 260g, junqianzi 220g, duckbill huang 160g, pamao fruit 240g, chicken dung tree 130g, red thorn vine 310g , Libai 180g, Chafengtong 280g and Shimoda chrysanthemum 140g;

[0069] Its preparation method comprises the following steps:

[0070] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 85% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Ethanol solvent, drying, obtains ...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating liver-qi stagnation type breast cancer and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine is prepared from the following crude drugs: root and rhizome of rheum hotaoense C.Y.Cheng et C. T. Kao, whole grass of pogonatherum paniceum, whole grass of lysimachia hui diels ex hand.-mazz., herb of tagua passionflower, mactra clam shell powder, emarginate amaranth herb or seed, fruit of date plum, herb of dry falsepimpernel, insect gall in sheath of root leaf of miscanthus floridulus (Labill.) warb., root of lasianthus hirsutus, root of rosa multiflora, rhizome of hicriopteris glauca, stem, branch and leaf of zanthoxylum rhetsoides and whole grass of adenostemma lavenia. The traditional Chinese medicine provided by the invention has the beneficial effects that the liver-qi stagnation type breast cancer can be treated by means of combining with surgery, radiotherapy and chemotherapy of Western medicine, the pertinence is strong, the treatment effect of Western medicine is effectively provided, the medicine is free from toxic and side effects, adverse effects of Western medicine are reduced or eliminated, and meanwhile the survival time of a patient who suffers from the breast cancer can be obviously prolonged.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating liver-qi stagnation type breast cancer and a preparation method thereof. Background technique [0002] Breast cancer is one of the most common malignant tumors in women. According to statistics, the incidence rate accounts for 7-10% of all kinds of malignant tumors in the whole body. It is second only to uterine cancer in women. Its incidence is often related to genetics, and 40-60 Between the ages, women's incidence rate before and after menopause is higher, and only about 1-2% breast patients are men. Malignant tumors usually occurring in the glandular epithelium of the breast. It is one of the most common malignant tumors that seriously affects women's physical and mental health and even threatens their lives. Breast cancer is rare in men. The pathogenesis of breast cancer is no...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61K9/16A61K9/20A61P15/14A61P35/00A61K35/618
CPCA61K36/899A61K9/1652A61K9/2059A61K35/618A61K36/11A61K36/185A61K36/21A61K36/28A61K36/44A61K36/708A61K36/73A61K36/74A61K36/758A61K36/80A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 姜永华
Owner 姜永华
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