Unlock instant, AI-driven research and patent intelligence for your innovation.

A kind of injectable bioactive bone cement material and preparation method thereof

A bioactive, bone cement technology, used in medical science, prosthesis, etc., can solve the problems of low pressure and flexural strength, poor mechanical properties, etc., and achieve good clinical operability, good performance, preparation and processing. simple method effect

Active Publication Date: 2019-08-30
PEKING UNIV SCHOOL OF STOMATOLOGY
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The purpose of the present invention is to solve the technical problems of poor mechanical properties, pressure resistance and low flexural strength of existing materials, and to provide an injectable bioactive bone cement material with good mechanical properties, high pressure resistance and high flexural strength and its preparation method

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of injectable bioactive bone cement material and preparation method thereof
  • A kind of injectable bioactive bone cement material and preparation method thereof
  • A kind of injectable bioactive bone cement material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) Weigh 115g of calcium carbonate, 28g of silicon dioxide, 2.9g of aluminum oxide, and 4.1g of ferric oxide, and put them into a ball mill jar with a ball-to-material ratio of 30:1, a speed of 400 rpm, and ball mill for 12 hours;

[0032] (2) After the ball milling is completed, take out the mixed material, dry and cool it, put it into a mold, press it into a disc shape with a pressure of 10Mpa on a hydraulic press, and keep the pressure for 15 minutes;

[0033] (3) Put the pressed disc into a muffle furnace for calcination, the heating rate is 10°C / min, keep at 800°C for 3 hours, then rise to 1450°C, hold for 2 hours, take it out and air cool to room temperature;

[0034] (4) Utilize the high-energy ball mill to pulverize the prepared material, and pass through a 200-mesh sieve to obtain a powdery material;

[0035] (5) Take 60% of the powdered material obtained in step (4), including 35% of tricalcium silicate, 10% of dicalcium silicate, 6% of calcium silicate, 5% o...

Embodiment 2

[0039] (1) Weigh 120g of calcium carbonate, 25g of silicon dioxide, 2.4g of aluminum oxide, and 3.4g of ferric oxide, and put them into a ball mill jar with a ball-to-material ratio of 20:1, a speed of 400 rpm, and ball mill for 10 hours;

[0040] (2) After the ball milling is completed, take out the mixed material, dry and cool it, put it into a mold, press it into a disc shape with a pressure of 10Mpa on a hydraulic press, and keep the pressure for 15 minutes;

[0041](3) Put the pressed disc into a muffle furnace for calcination, the heating rate is 10°C / min, keep at 800°C for 3 hours, then rise to 1450°C, hold for 2 hours, take it out and air cool to room temperature;

[0042] (4) Utilize the high-energy ball mill to pulverize the prepared material, and pass through a 200-mesh sieve to obtain a powdery material;

[0043] (5) Take 50% of the powdered material obtained in step (4), wherein, tricalcium silicate 25%, dicalcium silicate 5%, calcium silicate 6%, tricalcium alumi...

Embodiment 3

[0047] (1) Weigh 126g of calcium carbonate, 23g of silicon dioxide, 2.4g of aluminum oxide, 3.4-4.1g of iron tetroxide, and put them into a ball mill jar with a ball-to-material ratio of 10:1 and a speed of 400 rpm. 5h;

[0048] (2) After the ball milling is completed, take out the mixed material, dry and cool it, put it into a mold, press it into a disc shape with a pressure of 10Mpa on a hydraulic press, and keep the pressure for 15 minutes;

[0049] (3) Put the pressed disc into a muffle furnace for calcination, the heating rate is 10°C / min, keep at 800°C for 3 hours, then rise to 1450°C, hold for 2 hours, take it out and air cool to room temperature;

[0050] (4) Utilize the high-energy ball mill to pulverize the prepared material, and pass through a 200-mesh sieve to obtain a powdery material;

[0051] (5) Take 30% of the powdered material obtained in step (4), wherein, 20% of tricalcium silicate, 2% of dicalcium silicate, 3% of calcium silicate, 1% of tricalcium alumina...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to an injectable bioactive bone cement material and a preparation method thereof. The technical problems that an existing material is poor in mechanical performance and not high in pressure resistance and tensile strength are solved. The material is composed of bioactive ceramic powder, high-molecular polymer and additives. The invention meanwhile provides the preparation method of the injectable bioactive bone cement material. The injectable bioactive bone cement material can be widely used in the field of preparation of repair materials for surgical operation.

Description

technical field [0001] The invention relates to repair materials for surgical operations, in particular to an injectable bioactive bone cement material and a preparation method thereof. Background technique [0002] The orthopedic department faces many bone defects caused by trauma, tumor, infection, congenital defects and other reasons every day. However, the pain of autologous transplantation and the rejection of allograft make it difficult for traditional bone transplantation technology to meet the needs of treatment. one of the problems. [0003] Over the years, scientists from various countries have been committed to the research and development of ideal bone repair materials, but the traditional bone defect repair materials currently used clinically limit their application due to their own defects. An ideal bone defect repair material should meet the following requirements: ①Easy to form and can fill irregular bone cavities; ②It can solidify itself in the environment,...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/42
Inventor 张学慧袁慎坡柴媛
Owner PEKING UNIV SCHOOL OF STOMATOLOGY