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Antibacterial preparation and preparation method thereof

A preparation and regulator technology, applied in the direction of antifungal agents, pharmaceutical formulations, aerosol delivery, etc., can solve the problems of different treatment range and effect, single use range, and inability to specifically target specific bacteria, etc., to achieve good biological Compatibility, low cytotoxicity, effect of alleviating discomfort

Inactive Publication Date: 2016-11-16
武汉德仁科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many kinds of antibacterial lotions or capsules on the market, with different treatment ranges and effects, and cannot specifically target the exact bacteria; and the scope of use is single

Method used

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  • Antibacterial preparation and preparation method thereof
  • Antibacterial preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0023] An antibacterial preparation, each 100mL preparation is composed of the following ingredients: 0.1-0.5g of chlorhexidine acetate, 0.1-5g of menthol, 0.1-3g of borneol, 0.1-2g of glycerin, 4-10g of ethanol, an appropriate amount of pH regulator, and The amount is purified water.

[0024] Chlorhexidine acetate is an antibacterial preservative, which has bactericidal effect on Staphylococcus aureus, Streptococcus, Escherichia coli, anaerobic propionibacterium and Candida albicans. Borneol is used on the skin and mucous membranes to clear away heat, reduce swelling, analgesia, inhibit bacteria and have a cool feeling. Therefore, borneol is often used in preparations to exert anti-inflammatory, analgesic, antibacterial, analgesic, antipruritic and antiseptic effects; pharmacological antibacterial Experiments have shown that borneol has antibacterial effects on Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, etc. At the same time, borneol can promote the ab...

Embodiment 2

[0031] An antibacterial preparation, each 100mL preparation is composed of the following ingredients: 0.1-0.5g of chlorhexidine acetate, 0.1-5g of menthol, 0.1-3g of borneol, 0.1-2g of glycerin, 4-10g of ethanol, an appropriate amount of pH regulator, and The amount is purified water.

[0032] Further, every 100mL of the preparation also contains 0.25-2g of carbomer.

[0033] The preparation method of above-mentioned antibacterial preparation, comprises the following steps:

[0034] 1) Dissolving the above-mentioned glycerin in purified water to obtain a uniform glycerin solution;

[0035] 2) Add the above-mentioned chlorhexidine acetate to the above-mentioned glycerin solution, and stir while adding;

[0036] 3) Add above-mentioned borneol to ethanol, add menthol and stir evenly;

[0037] 4) Evenly disperse the carbomer in pure water and soak it. After fully dissolving, mix it with the uniformly stirred solution in 2) and 3), add a pH regulator to adjust the pH value, and ...

Embodiment 3

[0039] An antibacterial preparation, each 100mL preparation is composed of the following ingredients: 0.1-0.5g of chlorhexidine acetate, 0.1-5g of menthol, 0.1-3g of borneol, 0.1-2g of glycerin, 4-10g of ethanol, an appropriate amount of pH regulator, and The amount is purified water.

[0040] The preparation method of above-mentioned antibacterial preparation, comprises the following steps:

[0041] 1) Dissolving the above-mentioned glycerin in purified water to obtain a uniform glycerin solution;

[0042] 2) Add the above-mentioned chlorhexidine acetate to the above-mentioned glycerin solution, and stir while adding;

[0043] 3) Add above-mentioned borneol to ethanol, add menthol and stir evenly;

[0044] 4) Mix the homogeneously stirred solutions in 2) and 3), add a pH regulator to adjust the pH value, and stir for 30 minutes to obtain a liquid antibacterial agent, and then put the liquid antibacterial agent into the foam emulsion generating device.

[0045] Preferably, ...

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PUM

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Abstract

The embodiment of the invention discloses an antibacterial preparation and a preparation method thereof. The antibacterial preparation adopts compatibility of chlorhexidine acetate, borneol, menthol and glycerol, can effectively kill pathogenic bacteria and has good killing effect on pathogenic bacteria resulting in gynecological inflammation, namely pathogens such as staphylococcus aureus, candida albicans and escherichia coli, antibacterial rate is more than or equal to 90%, and the lowest content of heavy metals is less than 1ppm. The antibacterial preparation disclosed by the embodiment of the invention also has good biocompatibility, low cytotoxicity and no delayed type hypersensitivity; and each index meets relevant national standards or regulations. Meanwhile, the antibacterial preparation has good anti-inflammation, sterilization and itching relieving effects, is wide in application range and can also be applied to antibacteria and anti-inflammation of human skin and mucosae.

Description

technical field [0001] The invention relates to the technical field of medicine preparation, in particular to an antibacterial preparation and a preparation method thereof. Background technique [0002] Gynecological diseases threaten the health of women in our country and tend to be younger; and they are usually incurable for a long time, which brings great inconvenience to normal life and work. At present, there are many kinds of antibacterial lotions or capsules on the market, with different treatment ranges and effects, and cannot specifically target the exact germs; and the scope of use is single. Contents of the invention [0003] The object of the present invention is to provide a kind of antibacterial preparation and preparation method thereof, to solve the above technical problems. [0004] In order to solve the above-mentioned technical problems, the technical solution adopted in the embodiments of the present invention is an antibacterial preparation, each 100m...

Claims

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Application Information

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IPC IPC(8): A61K31/155A61K9/08A61K9/06A61K47/10A61K47/32A61P15/00A61P31/10A61P15/02A61K9/12A61K47/22A61K47/26
CPCA61K9/0034A61K9/06A61K9/08A61K9/122A61K31/045A61K31/155A61K47/10A61K47/22A61K47/26A61K47/32A61K2300/00Y02A50/30
Inventor 罗仁德
Owner 武汉德仁科技开发有限公司
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