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A kind of pharmaceutical composition for dermatitis, application, preparation and preparation method thereof

A composition and drug technology, which can be used in drug combinations, pharmaceutical formulations, active ingredients of heterocyclic compounds, etc., and can solve problems such as easy recurrence and drug dependence in patients.

Active Publication Date: 2019-01-29
CHENGDU AKEOR BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the treatment of rashes, it is easy to cause drug dependence in patients, and it is easy to relapse

Method used

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  • A kind of pharmaceutical composition for dermatitis, application, preparation and preparation method thereof
  • A kind of pharmaceutical composition for dermatitis, application, preparation and preparation method thereof
  • A kind of pharmaceutical composition for dermatitis, application, preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] The present invention provides a preparation method of the pharmaceutical composition and the composition gel, and the composition components include by weight fraction: 9 parts of matrine, 3 parts of osthole, and Kochia saponin Ic6 parts, 9 parts of paeonol, 24 parts of glycyrrhizic acid, 36 parts of menthol, 15 parts of bisabolol; parts by weight are in grams;

[0062] 1. Dissolving the above components in an appropriate amount of absolute ethanol to make a clear solution to obtain the composition;

[0063] 2. Mix and stir the clear solution with 1050 parts of PEG-50 hydrogenated castor oil and nonylphenol polyether-14 at 55-70°C to obtain a transparent oily substance wrapped in an emulsifier;

[0064] 3. After wetting 5 parts of carbomer with propylene glycol and distilled water, place it to make the carbomer fully swell and form a hydration colloid;

[0065] 4. Mix the transparent oil in step 2) with distilled water evenly to form a watery stable solution;

[0066...

Embodiment 2～5

[0069]The difference between Examples 2-5 and Example 1 lies in that the formulation of the components of the pharmaceutical composition is shown in Table 1.

[0070] Table 1 pharmaceutical composition component formula of the present invention

[0071]

Embodiment 6

[0073] Embodiment 6 The raw materials used in the composition of the present invention are Sophora flavescens, Fructus Cnidii, Fructus Kochia, Cortex Moutan, Glycyrrhizae, Menthol, Bisabolol; 1c, said paeonol, said glycyrrhizic acid are respectively the extract of said Sophora flavescens, said Cnidium fruit, said Kochia scoparia, said Moutan cortex, said licorice, parts by weight are in grams, so The raw material formula is shown in Table 2.

[0074] Table 2 Pharmaceutical composition raw material formula of the present invention

[0075]

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Abstract

The invention discloses a pharmaceutical composition for dermatitis. The pharmaceutical composition is prepared from, by weight, 3-20 parts of sophocarpidine, 1-10 parts of cnidium lactone, 2-15 parts of fructus kochiae saponin Ic, 3-20 parts of paeonol, 8-40 parts of glycyrrhizic acid, 10-48 parts of menthol and 5-30 parts of bisabolol. The pharmaceutical composition has itching relieving and inflammation diminishing effects, can be used for treating insect dermatitis and contact dermatitis, can take effect quickly and is short in treatment course, high in cure rate, convenient to use and free of allergenicity or irritation to skin. The preparing process is mature, and quality is controllable.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for dermatitis, an application, a preparation and a preparation method thereof. Background technique [0002] Dermatitis is the abbreviation of a kind of skin inflammation reaction, and the factors that cause dermatitis are complex and diverse. Can be divided into: contact dermatitis, insect bite dermatitis, neurodermatitis, sunburn dermatitis, drug-induced dermatitis, hormone-dependent dermatitis, etc. The usual causes are: chronic disease infection, endocrine and metabolic changes, food and inhalant allergies, etc. The common symptoms caused by this are erythema, edema, accompanied by papules, blisters or oozing. [0003] Among them, contact dermatitis refers to the acute inflammatory reaction of the skin caused by the contact of the skin or mucous membranes with certain external pathogenic substances, which can also gradually...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/704A61P17/00A61K31/4375A61K31/37A61K31/12A61K31/045
CPCA61K31/045A61K31/12A61K31/37A61K31/4375A61K31/704A61K2300/00
Inventor 赵良彬刘杨川
Owner CHENGDU AKEOR BIOTECH CO LTD