Compound selectively recognizing mercury ions and preparation method and application thereof

Abstract

The invention mainly aims to provide a compound selectively recognizing mercury ions and a preparation method and application thereof. The preparation method includes following steps: 1), providing a first solution which contains a rhodamine compound dispersed in a first solvent; 2), heating the first solution, and mixing the first solution with a hydrazine hydrate solution for reaction to obtain rhodamine hydrazide; 3), providing a second solution which contains rhodamine hydrazide dispersed in a second solvent; 4), heating the second solution, mixing the second solution with a Lawson reagent, reacting in an inertial gas atmosphere, and separating out sulfur hydrazide; 5), providing a third solution which contains sulfur hydrazide dispersed in a third solvent; 6), heating the third solution, mixing the third solution with terephthalaldehyde, reacting under catalysis of glacial acetic acid and in inertial gas, and filtering to obtain a product. The synthesis process is free of byproduct generation, and the compound is simple in purifying operation and has good selective recognition effect on Hg2+.

Description

technical field [0001] The invention belongs to the field of detection of heavy metal ions by fluorescent probe molecules, and in particular relates to a compound for selectively recognizing mercury ions and its preparation method and application. Background technique [0002] Hg 2+ It is a heavy metal ion with strong physiological toxicity. Its small amount of oral administration, inhalation or contact can cause damage to the brain and liver, leading to the collapse of the human immune system. Therefore, people are paying more and more attention to the research on its content detection. Fluorescent molecular probes have been widely used in chemical, environmental, biological analysis and other fields due to their advantages of easy operation, rapid response, high sensitivity, good selectivity, and in-situ, real-time rapid analysis. Therefore, the design and synthesis of novel fluorescent probes with excellent performance has become one of the research hotspots in the inte...

AI Technical Summary

Problems solved by technology

[0004] In the existing reports, the synthesis of many fluorescent probe molecules has the disadvantages of difficult purification, sensitivity to water, and low single selectivity in application, which limits its application to a certain extent.

The purification process in the synthesis of existing fluorescent probe molecules is time-consuming and labor-intensive; and the anhydrous state of the reaction system must be ensured during the synthesis process

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