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A kind of aspergillus niger effervescent tablet

A technology for Aspergillus niger and effervescent tablets, applied in the field of Aspergillus niger effervescent tablets and preparation thereof, can solve the problems of unsuitable liquid properties for storage and transportation in large quantities, the harm of unknown growth of tobacco with biocontrol effect, and the pollution of miscellaneous bacteria.

Inactive Publication Date: 2019-10-29
GUIZHOU UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although Aspergillus niger fermentation broth has good antibacterial activity, it is not suitable for large-scale storage and transportation due to the nature of the liquid. If it is not properly preserved during long-term storage, it will be contaminated by miscellaneous bacteria, which will cause unknown harm to the biocontrol effect and tobacco growth. Therefore, we Further processing and optimization of Aspergillus niger fermentation broth products

Method used

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  • A kind of aspergillus niger effervescent tablet
  • A kind of aspergillus niger effervescent tablet
  • A kind of aspergillus niger effervescent tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: the preparation of effervescent tablet

[0028] Instruments and reagents (unless otherwise specified, all instruments and reagents are commercially available products):

[0029] Electric vacuum drying oven, electric heating constant temperature drying oven, balance; LYO-1 freeze drying equipment (Shanghai Tofflon Co., Ltd.), CS101-2A electric heating drying oven (Chongqing Yinhe Experimental Instrument Co., Ltd.), water bath (Beijing Kewei Yongxin Experimental Instrument Equipment Factory), RE-52A rotary evaporator (Shanghai Yarong Biochemical Instrument Factory), multi-purpose vacuum pump for circulating water (Zhengzhou Dufu Instrument Factory), inclined high-speed universal pulverizer (Beijing Zhongxing Weiye Instrument Co., Ltd.), TDP1 single stamping Tablet machine (Shanghai Tianfan Pharmaceutical Machinery Manufacturing Factory), 78X-Z Tablet Four-purpose Tester (Shanghai Huanghai Drug Testing Instrument Factory).

[0030] Lactose, Mannitol, MCC, Be...

Embodiment 2

[0040] Embodiment 2: the preparation of effervescent tablet

[0041] According to the method described in Example 1, according to Aspergillus niger fermentation concentrate crude extract powder 20 parts by weight, NaHCO 3 39.5 parts by weight, 45 parts by weight of citric acid, 2 parts by weight of polyethylene glycol 6000, and 1.5 parts by weight of PVP.

Embodiment 3

[0042] Embodiment 3: the preparation of effervescent tablet

[0043] According to the method described in Example 1, according to the Aspergillus niger fermentation concentrate crude extract powder 18 parts by weight, NaHCO 3 45 parts by weight, 50 parts by weight of citric acid, 5 parts by weight of polyethylene glycol 6000, and 5 parts by weight of PVP.

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PUM

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Abstract

The invention relates to use of an Aspergillus niger effervescent tablet to control of tobacco bacterial wilt. The Aspergillus niger xj is separated by Fungi resources institute of Guizhou University, and is currently preserved at China Center for Type Culture Collection (address: Wuhan University, Wuhan China) with a preservation number of CCTCCNO:M206021. The Aspergillus niger effervescent tablet contains Aspergillus niger, an adhesive, a lubricant, citric acid and sodium bicarbonate. The effervescent tablet has good foaming capacity, disintegration time and hardness, and has better inhibiting effect on tobacco bacterial wilt.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to an Aspergillus niger (Aspergillus niger xj) effervescent tablet and a preparation method thereof. Background technique [0002] Aspergillus niger is a common fungus belonging to the half-known genus Aspergillus. Aspergillus niger can be widely used in the processing of protein products, feed processing and waste treatment. The present application utilizes the secondary metabolites produced by Aspergillus niger in the growth process to inhibit tobacco Ralstonia solanacearum. In the prior art, there is an example of preventing and controlling tobacco environmental disease by Aspergillus niger, as Chinese patent CN103146600A discloses utilizing Aspergillus niger (Aspergillus niger) Ty-3 to prevent and treat tobacco bacterial wilt. However, the application is not clear about pathogenic bacteria isolation and fungal culture conditions. For example, R. solanacearum is a bacterium, a sing...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N25/34A01N63/04A01P1/00
CPCA01N25/34A01N63/30
Inventor 李祝丛铭肖洋李玉环郭博恺万科
Owner GUIZHOU UNIV