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Formula of antifebrile gel roll-on bead and preparation method

A gel composition and prescription technology, applied in the field of drug research, can solve problems such as inability to achieve immediate cooling, injury to children, slow fever reduction, etc.

Inactive Publication Date: 2017-03-15
TIANJIN POLYTECHNIC UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For young children, it is generally recommended to use physical methods to reduce fever, such as cold compresses, body scrubs with warm water, gel patches, etc. However, these methods are slow to reduce fever and cannot achieve immediate cooling effects
In contrast, rubbing with 70% ethanol can reduce fever quickly, but because it contains ethanol, it will be absorbed through the skin and cause harm to young children, especially those who are allergic to alcohol, which may cause irreparable and serious consequences

Method used

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  • Formula of antifebrile gel roll-on bead and preparation method
  • Formula of antifebrile gel roll-on bead and preparation method
  • Formula of antifebrile gel roll-on bead and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The antipyretic gel roll-on formula consists of the following:

[0024]

[0025] Preparation:

[0026] a) Weigh the aloe extract and the honeysuckle extract according to the prescription amount, dissolve them in water and mix them evenly, then add the prescription amount of vitamin C, and mix evenly to obtain the water phase;

[0027] b) Dissolve borneol and menthol in an appropriate amount of glycerin according to the prescription amount, then add lavender essential oil and peppermint essential oil, and mix evenly to obtain an oil tank;

[0028] c) Add the oil phase, water phase, glycerin, carbomer 940, sodium benzoate, ethylparaben, triethanolamine, and water into the homomixer at 50-70°C according to the prescribed amount, and mix for 5-15 minutes , to obtain the antipyretic gel composition.

[0029] d) Divide the obtained antipyretic gel composition into rollers, and sterilize it by radiation to obtain antipyretic gel rollers.

Embodiment 2

[0031] The antipyretic gel roll-on formula consists of the following:

[0032]

[0033]

[0034] Preparation:

[0035] a) Weigh the aloe extract and the honeysuckle extract according to the prescription amount, dissolve them in water and mix them evenly, then add the prescription amount of vitamin C, and mix evenly to obtain the water phase;

[0036] b) Dissolve borneol and menthol in an appropriate amount of glycerin according to the prescription amount, then add lavender essential oil and peppermint essential oil, and mix evenly to obtain an oil tank;

[0037] c) Add the oil phase, water phase, glycerin, sodium dodecylbenzenesulfonate, xanthan gum, sodium benzoate, phenoxyethanol, and water into a homogeneous mixer at 50-70°C according to the prescribed amount, and mix After 5-15 minutes, the antipyretic gel composition is obtained.

[0038] d) Divide the obtained antipyretic gel composition into rollers, and sterilize it by radiation to obtain antipyretic gel roller...

Embodiment 3

[0040] The antipyretic gel roll-on formula consists of the following:

[0041]

[0042]

[0043] Preparation:

[0044] a) Weigh the aloe extract and the honeysuckle extract according to the prescription amount, dissolve them in water and mix them evenly, then add the prescription amount of vitamin C, and mix evenly to obtain the water phase;

[0045] b) Dissolve borneol and menthol in an appropriate amount of glycerin according to the prescription amount, then add lavender essential oil and peppermint essential oil, and mix evenly to obtain an oil tank;

[0046] c) Add the oil phase, water phase, glycerin, propylene glycol, xanthan gum, sodium benzoate, phenoxyethanol, and water into the homogeneous mixer at 50-70°C according to the prescription amount, and mix for 5-15 minutes to obtain the Hot gel composition.

[0047] d) Divide the obtained antipyretic gel composition into rollers, and sterilize it by radiation to obtain antipyretic gel rollers.

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Abstract

The invention provides a formula of antifebrile gel roll-on bead and a preparation method. According to the invention, the problem that traditional physical methods such as cold compress, warm water rubdown, gel paste, etc. have slow antifebrile effect is overcome, and ethanol is not used so as to avoid ethanol absorption and anaphylactic reaction of human body. More importantly, volatile components in natural Chinese herbal medicines are used as a main antipyretic, which belongs to a physical cooling process and avoids side-effect caused by drug use for defervesce. In addition, mint and lavender essential oil can have effects of raising spirit and restoring consciousness and soothing emotions. The product is safe and nontoxic, has definite therapeutic effect, is convenient to use and carry and is suitable for defervesce processing for people of all ages.

Description

technical field [0001] The invention provides a formula and a preparation method of antipyretic gel roll-on beads, which belong to the field of drug research. [0002] technical background [0003] Fever, also known as fever, is an accommodative increase in body temperature (over 0.5°C) caused by the action of a pyrogen that moves the temperature setpoint up. There are many reasons for causing fever, the most common being infection (including various bacterial infections, viral infections, mycoplasma infections, etc.), followed by connective tissue diseases (ie collagen diseases), malignant tumors, etc. Fever is both beneficial and harmful to the human body. The immune function of the human body is significantly enhanced during fever, which is conducive to eliminating pathogens and promoting the recovery of diseases. Moreover, fever is also a sign of disease. Therefore, when the body temperature is not too high, you can reduce the discomfort caused by fever by drinking plen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/886A61K36/896A61K9/06A61P29/00A61F7/02A61K31/045A61K31/375
CPCA61K36/886A61F7/02A61F2007/0215A61F2007/0217A61K9/0014A61K9/06A61K31/045A61K31/375A61K36/355A61K36/53A61K36/534A61K36/896A61K47/32A61K47/36A61K2300/00
Inventor 郭文娟李香华张瑞平朱大伟
Owner TIANJIN POLYTECHNIC UNIV
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