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Marbofloxacin soluble pulvis

A soluble powder, marbofloxacin technology, applied in the field of biomedicine, can solve the problems of high heat sensitivity, inconvenient transportation, easy decomposition and deterioration, etc., and achieve the effect of good water solubility, convenient transportation and low cost

Inactive Publication Date: 2017-04-26
JIANGSU HFQ BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Marbofloxacin solution has high heat sensitivity, is easy to decompose and deteriorate, and is inconvenient to transport

Method used

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  • Marbofloxacin soluble pulvis
  • Marbofloxacin soluble pulvis
  • Marbofloxacin soluble pulvis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Marbofloxacin soluble powder, which is mainly based on marbofloxacin and sodium carbonate (containing 10% marbofloxacin, 45% sodium carbonate), with an appropriate amount of spices, soluble correctives and soluble fillers. It is prepared by conventional methods such as drying, weighing, crushing, stirring, mixing, inspection, measurement, and packaging.

[0024] The formula is:

[0025]

[0026] Specific production method:

[0027] (1) Dry the above raw materials to make the water content less than 5%.

[0028] (2) Weigh, fully pulverize the raw materials of the above components, and use 60 to 80 mesh sieve for sieving treatment;

[0029] (3) Pour the above-mentioned raw materials after sieving into the V-type mixer, and stir them for 25 minutes to mix evenly;

[0030] (4) Sampling and testing to check the percentage of raw material content, whether the fineness of powder meets the standard, whether the moisture content is qualified, etc.;

[0031] (5) Measure and weigh, pack into...

Embodiment 2

[0033] The marbofloxacin soluble powder in this embodiment contains 10% marbofloxacin, 45% sodium carbonate, 1% musk flavor, 30% soluble corrective agent, and 14% starch. Dry 10 grams of marbofloxacin, 45 grams of sodium carbonate, 1 gram of musk flavor, 30 grams of sucrose, and 14 grams of starch to make the water content less than 5%, weigh it, fully crush the raw materials of the above components, and use 60 to 80 mesh sieve for sieving treatment. Pour the sieved raw materials and auxiliary materials into the V-type mixer, fully stir for 25 minutes, and mix well.

[0034] Sampling and testing to check the percentage of raw materials, whether the fineness of the powder meets the standard, whether the water content is qualified, etc., measure and weigh, pack into a bag, and pack 5 grams, 10 grams or 100 grams of the above powder into each bag to obtain Mabosha Star soluble powder.

Embodiment 3

[0036] The marbofloxacin soluble powder in this embodiment contains 20% marbofloxacin, 10% sodium carbonate, 1% musk flavor, 25% lactose, and 44% glucose. Dry 20 grams of marbofloxacin, 15 grams of sodium carbonate, 1 gram of musk flavor, 25 grams of lactose, and 44 grams of glucose to make the water content less than 5%. Weigh it. The raw materials of the above components are fully crushed and used 60 to 80 mesh sieve is sieved. Pour the sieved raw materials and auxiliary materials into the V-type mixer, fully stir for 25 minutes, and mix evenly.

[0037] Sampling and testing to check the percentage of raw materials, whether the fineness of the powder meets the standard, whether the water content is qualified, etc., weigh it, pack it into a bag, and fill each bag with 5 g, 10 g or 100 g of the above powder to obtain Mabosha Star soluble powder.

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PUM

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Abstract

The invention discloses a marbofloxacin soluble pulvis. The marbofloxacin soluble pulvis comprises, by weight, 4.0-25% of marbofloxacin, 1.0-45% of sodium carbonate, 0.1-1.0% of a perfume, and the balance of a soluble filler. The marbofloxacin soluble pulvis prepared through a method disclosed in the invention has the characteristics of simplicity in use, low cost, complete fragrance, stability in storage, convenience in transportation, and good water solubility. An aqua prepared in the invention greatly improves the curative effects of themarbofloxacin soluble pulvis, is a novel wide-spectrum and high-efficiency special pulvis for animals, and enriches the variety of antibiotics in the veterinary medicine market.

Description

Technical field [0001] The present invention relates to the technical field of biomedicine, in particular to a veterinary antibiotic drug preparation, in particular to a marbofloxacin soluble powder and a preparation method thereof. Background technique [0002] Marbofloxacin, also known as Marbofloxacin, is the third-generation quinolone antibacterial drug for animals. Marbofloxacin inhibits the growth of bacteria by inhibiting the DNA transcriptase of bacteria. It has antibacterial effects on Gram-negative bacteria, Gram-positive bacteria and Mycoplasma. It can be absorbed well through oral and injection administration, and has toxic side effects. Lower. And when the drug is used as a veterinary drug, there are few adverse reactions, and it is still effective against pathogens resistant to the following drugs such as erythromycin, lincomycin, chloramphenicol, doxycycline, and sulfa drugs. [0003] Marbofloxacin is used to treat various skin, digestive and respiratory infections...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K31/5395A61K47/02A61P31/04
CPCA61K31/5395A61K9/143
Inventor 廖家友
Owner JIANGSU HFQ BIO TECH CO LTD
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