Inactivated pentavaccine for flounder paralichthys and preparation method of inactivated pentavaccine

Abstract

The invention discloses an inactivated pentavaccine for flounder paralichthys and a preparation method of the inactivated pentavaccine. The inactivated pentavaccine consists of the following formulated components in parts by weight: 5-8 parts of glycine, 5-15 parts of complex vitamins, 7-9 parts of aspartic acid, 13-15 parts of vibrio anguillarum, 8-10 parts of vibrio scophthalmi, 2-4 parts of vibrio alginolyticus, 2-4 parts of an astragalus polysaccharide adjuvant, 12-13 parts of medicinal starch, 4-6 parts of vibrio vulnificus, 4-5 parts of edwardsiella tarda liquid, 10-20 parts of maltodextrin, 1-3 parts of vibrio harveyi and 0.5-0.7 part of a mildew preventive. The inactivated pentavaccine provided by the invention has multiple immune effects; and the inactivated pentavaccine, as being inoculated once, can effectively prevent infection of five bacterial pathogenic bacteria of the flounder paralichthys; therefore, a basis is provided for the research and development of inactivated multivalent vaccines for marine fish.

Description

technical field [0001] The invention relates to the field of seawater fish vaccines, in particular to a five-linked inactivated vaccine for flounder and flounder and a preparation method thereof. Background technique [0002] The Yellow Sea Fisheries Research Institute of the Chinese Academy of Fishery Sciences has conducted comprehensive and systematic disease epidemiological research on the cultured flounder and flounder in my country, and discovered more than 20 typical disease symptoms of flounder and flounder, and carried out detailed investigations on their pathogens. ,Deep research. The study found that most of the diseases of flounder flounder are caused by bacterial pathogens, and Vibrio anguillaris, Vibrio turbot, Vibrio harvey, Vibrio alginolyticus, and Edwardsiella tarda are the most important factors in the breeding process of flounder flounder. The five most common pathogenic bacteria in rats can cause a variety of obvious symptoms such as fin rot, ascites, ent...

AI Technical Summary

Problems solved by technology

The long-term use of antibiotics will not only easily lead to drug resistance of pathogenic bacteria and increase the difficulty of subsequent disease prevention, but also the problem of drug residues is also related to the food quality and safety of commercial fish.