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Preparation and application of lucid ganoderma fully-active material

An active substance, the technology of Ganoderma lucidum, applied in the preparation and application field of all active substances of Ganoderma lucidum, can solve the problems of incomplete preparation of active substances, low utilization rate, cumbersome production process, etc., to facilitate industrial production, enhance immunity, and simplify extraction The effect of steps

Inactive Publication Date: 2017-06-30
FUJIAN AGRI & FORESTRY UNIV
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  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to provide a preparation method and application of all active substances of Ganoderma lucidum, which can solve the existing problems of incomplete preparation of active substances, cumbersome manufacturing process, low utilization rate, etc. Good application prospect

Method used

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  • Preparation and application of lucid ganoderma fully-active material

Examples

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Effect test

preparation example Construction

[0022] A kind of Ganoderma lucidum active substance, its preparation method comprises the steps:

[0023] 1) Grind Ganoderma lucidum into fine powder with a grinder;

[0024] 2) According to the solid-liquid ratio of 1:10 g / mL, the obtained Ganoderma lucidum fine powder was used as a solvent by 95wt% ethanol solution, and ultrasonic-microwave synergistic extraction or ultrasonic-assisted extraction was carried out at 45°C for 3 times, each time for 0.5h, and then filtered , obtain Ganoderma lucidum 95wt% ethanol extract;

[0025] 3) According to the solid-liquid ratio of 1:10 g / mL, use 55wt% ethanol solution as the solvent for the remaining filter residue in step 2), and conduct ultrasonic-microwave synergistic extraction or ultrasonic-assisted extraction at 45°C for 3 times, each time for 0.5h , and then filtered to obtain Ganoderma lucidum 55wt% alcohol extract;

[0026] 4) According to the solid-liquid ratio of 1:10 g / mL, use deionized water as the solvent for the remaini...

Embodiment example 1

[0031] Implementation Case 1 A Ganoderma Lucidum Health Capsule for Regulating Blood Sugar and Blood Lipids

[0032] 1) Grind Ganoderma lucidum into fine powder, add 95wt% ethanol solution at a material-to-liquid ratio of 1:20 g / mL, conduct ultrasonic-assisted extraction at 60°C for 4 hours, and then filter to obtain 95wt% ethanol extract of Ganoderma lucidum;

[0033] 2) According to the material-to-liquid ratio of 1:20 g / mL, use 55wt% ethanol solution to extract the remaining filter residue in step 1) with ultrasonic assistance at 60°C for 3 hours, and then filter to obtain 55wt% ethanol extract of Ganoderma lucidum;

[0034] 3) Add tea tree mushroom and kelp to distilled water 10 times its weight, soak for 2 hours, boil for 1.5 hours with high heat, and filter; add distilled water 8 times its weight, boil with high heat for 1.5 hours, filter; add the obtained filter residue to its weight again 4 times the amount of distilled water, simmer for 2 h, filter; combine the filtra...

Embodiment example 2

[0036] Implementation Case 2 A Ganoderma Lucidum Health Granule for Regulating Blood Sugar and Blood Lipid

[0037] 1) Grind Ganoderma lucidum into fine powder with a pulverizer, add 95wt% ethanol solution at a material-to-liquid ratio of 1:30 g / mL, conduct ultrasonic-microwave co-extraction twice at 80°C for 1 hour each time, and then filter to obtain Ganoderma lucidum 95wt% alcohol extract;

[0038] 2) According to the solid-liquid ratio of 1:30 g / mL, the remaining filter residue in step 1) was extracted with 60wt% ethanol solution at 80 ° C for 2 times, 1 hour each time, and then filtered to obtain Ganoderma lucidum 60wt% alcohol extract;

[0039] 3) According to the solid-liquid ratio of 1:30 g / mL, use deionized water as a solvent to extract the remaining filter residue from step 2) at 90°C for 2 times with ultrasonic-microwave co-extraction, 1 hour each time, and then filter to obtain Ganoderma lucidum water extract;

[0040]4) The water extraction residue of step 3) w...

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Abstract

The invention discloses a preparation and application of a lucid ganoderma fully-active material. According to the lucid ganoderma fully-active material, lucid ganoderma serves as the raw material and is crushed, then sequentially extracted through polarity-increased ethanol solutions and water and then enzymolyzed through protease to obtain lucid ganoderma 85 wt%-95 wt% alcohol extract, lucid ganoderma 55 wt%-65 wt% alcohol extract, lucid ganoderma water extract and zymolyte, namely, to obtain the lucid ganoderma fully-active materials. The medical effect test shows that the lucid ganoderma fully-active materials can significantly reduce total cholesterol (TC) and triglyceride (TG) in serum, and according to the assistant and guide theories in traditional Chinese medicine as well as modern nutriology theories, can be compounded with other homologic active constituents by one or more to prepare functional food with effects of immunity enhancement, blood glucose, lipid and pressure regulation, liver protection and the like.

Description

technical field [0001] The invention belongs to the technical field of separation of natural active ingredients, and in particular relates to the preparation and application of ganoderma lucidum active substances. Background technique [0002] With the improvement of living standards and changes in the pace of life, the incidence of "three highs" known as "rich man's disease" is increasing, especially in middle-aged and elderly people over 50 years old. Hyperlipidemia can cause vascular embolism; high blood pressure can cause cerebral hemorrhage and cerebrovascular rupture; high blood sugar can cause diabetes. The number of people who die from cardiovascular and cerebrovascular diseases is as high as 15 million every year in the world, ranking first among various causes of death. But at present clinically commonly used oral hypoglycemic and blood fat medicines all have side effects, can cause the adverse reaction of digestive system, some also can cause measles, anemia, whi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L31/00A23L33/00
Inventor 刘斌郭伟灵陈弘培潘雨阳李田田贾瑞博吕旭聪花朋朋黄梓芮林占熺
Owner FUJIAN AGRI & FORESTRY UNIV
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