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Oral cavity care article for removing ozostomia and preparation method thereof

A technology for oral care and products, which is applied in the field of oral care products for removing bad breath and its preparation. It can solve the problems of not conducting corresponding tests to verify the efficacy, and achieve the effects of inhibiting bad breath bacteria, prolonging retention time and increasing solubility. Effect

Inactive Publication Date: 2017-08-04
GUANGZHOU WEIMEIZI IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The reason for the above shortcomings is that the unit or individual of the above-mentioned patents did not conduct an in-depth analysis of the mechanism of the composition components, and did not conduct corresponding tests to verify the efficacy of the composition or a single component, more from other reports. information to judge the effect of a substance or combination of substances

Method used

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  • Oral cavity care article for removing ozostomia and preparation method thereof
  • Oral cavity care article for removing ozostomia and preparation method thereof
  • Oral cavity care article for removing ozostomia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] A toothpaste for removing bad breath, parts by weight of each component:

[0059]

[0060] The preparation method is as follows:

[0061] (1) Add potassium citrate, sodium saccharin and sodium benzoate into water and stir to dissolve;

[0062] (2) Add sodium carboxymethyl cellulose to sorbitol and stir evenly, add PEG-400 and stir evenly;

[0063] (3) Add the homogeneous solution of step (2) to the solution of step (1) and stir evenly;

[0064] (4) zinc citrate is added in the solution of step (3) and stirred;

[0065] (5) Sodium lauryl sulfate is added in the hydrated silica and stirred evenly;

[0066] (6) Add the uniform powder of step (5) into the solution of step (4), and stir evenly;

[0067] (7) Add 4-isopropyl-3-methylphenol into the essence solution, and heat to dissolve in a water bath;

[0068] (8) Add the homogeneous solution of step (7) into the homogeneous paste of step (6), stir evenly, and pump air.

Embodiment 2

[0108] A toothpaste for removing bad breath of the present invention can also add Bawanghua extract, and the parts by weight of each component are as follows:

[0109]

[0110] The Bawanghua extract is to add Bawanghua to 15 times the quality of water, cold soak for 30min, heat and reflux in a water bath for 1h, filter, and leave the filtrate; add 15 times the quality of water to the dregs, then reflux for 1h, filter, and combine The filtrate was obtained by concentration.

[0111] The preparation method of this toothpaste is as follows:

[0112] (1) Add sodium citrate, sodium saccharin, sodium benzoate and Bawanghua extract into water and stir to dissolve;

[0113] (2) Add sodium carboxymethyl cellulose to sorbitol and stir evenly, add PEG-400 and stir evenly;

[0114] (3) Add the homogeneous solution of step (2) to the solution of step (1) and stir evenly;

[0115] (4) zinc citrate is added in the solution of step (3) and stirred;

[0116] (5) Sodium lauryl sulfate is...

Embodiment 3

[0139] 1.3.2 Solubility test results of zinc citrate

[0140] Table 6 Zinc citrate solubility test result

[0141]

[0142] Note: + means the liquid is turbid, ++ means the liquid is slightly turbid, +++ means the liquid is relatively clear, ++++ means the liquid is completely clear

[0143] The test results show that the combination of zinc citrate and potassium citrate or sodium citrate has a synergistic effect, and the combination of potassium citrate or sodium citrate and zinc citrate can increase the solubility of zinc citrate and release more Zinc ions enhance the antibacterial effect. At the same time, the dissolution of a large amount of zinc ions can prolong the retention time of zinc citrate or zinc ions in the oral mucosa and saliva, and exert a long-term antibacterial effect.

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Abstract

The invention discloses an oral cavity care article for removing ozostomia and a preparation method thereof. The oral cavity care is prepared from 4-isopropyl-3-methylphenol, zinc citrate and citrate, wherein the citrate is one or more of potassium citrate or sodium citrate; through being metered in parts by weight, the zinc citrate accounts for 0.5 to 2.0 parts; the 4-isopropyl-3-methylphenol accounts for 0.01 to 0.1 part; the weight ratio of the zinc citrate to potassium citrate is 1:(1.3 to 1.5); the weight ratio of the zinc citrate to the sodium citrate is 1:(1.2 to 1.35). The oral cavity care article has the advantages that the bacteria generating volatile sulfur compounds in the oral cavity can be inhibited / reduced, so that the goal of relieving the stomatogenous bad ozostomia is achieved.

Description

technical field [0001] The invention relates to the technology and belongs to the technical field of oral care, in particular to an oral care article for removing bad breath and a preparation method thereof. Background technique [0002] Bad breath, also known as halitosis, refers to a symptom that emits a peculiar smell when breathing or opening the mouth. Halitosis is quite common among adults, and epidemiological investigations show that the incidence of halitosis is higher. Liu et al. investigated 2000 Chinese aged 15-64, and the prevalence of halitosis was 27.5% (Xue N L, Shinada K, Xiao C C, et al. Oral malodor-related parameters in the Chinese general population[J]. Journal of Clinical Periodontology, 2006, 33(1):31-6). In Japan, 24% of adults over the age of 30 complained of bad breath symptoms; in the United States, 92% of dentists encountered patients who sought treatment for bad breath; nearly 50% of dentists encountered more than 6 patients with bad breath ever...

Claims

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Application Information

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IPC IPC(8): A61K8/365A61K8/34A61K8/9789A61Q11/00A61Q17/00A61P1/02A61P31/04A61P31/02
CPCA61K8/347A61K8/365A61K8/97A61Q11/00A61Q17/005
Inventor 陈敏珊李平李林祝智胜
Owner GUANGZHOU WEIMEIZI IND CO LTD
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