Bone repair biological ceramic scaffold material formed through individualized customization based on photocuring 3D printing technology and preparation method of bone repair biological ceramic scaffold material

Abstract

The invention relates to a preparation method of a biological ceramic scaffold material. The preparation method of the bone repair biological ceramic scaffold material formed through individualized customization based on photocuring 3D printing technology comprises the following steps: (1) establishing a health state diagram when the skeleton is not damaged by adopting the CT two-dimensional and three-dimensional imaging technologies, and by combining with the to-be-implanted defect skeleton state diagram, separating out the to-be-implanted skeleton state diagram; (2) converting CT data into 3D printing data by adopting special data software; and (3) preparing the bone defect biological ceramic repairing material in an individualized manner by adopting the photocuring 3D printing technology. The bone repair biological ceramic material prepared by adopting the method provided by the invention conforms to the individualized treatment principle, the preparation process is short is time and high in efficiency, and the prepared material has the accurate porosity, small errors, large compression-resisting strength and bending-resisting strength, and good biocompatibility.

Description

technical field [0001] The invention relates to a preparation method of a bioceramic support material. Background technique [0002] With the incidence of traumatic fractures and bone tumors increasing year by year, more and more patients have bone defects caused by trauma and tumors. However, treatment, especially the treatment of large bone defects, has always been one of the difficult problems in the field of orthopedics. Large bone defects not only require a large amount of bone graft, but also have high requirements for postoperative mechanical properties. At present, the most widely used methods for clinical treatment of bone defects include bone grafting, artificial substitute replacement, and distraction osteogenesis, but each has its own limitations. For example, autologous bone extraction itself is a re-injury to the patient, which greatly increases the suffering of the patient, and the amount of donor bone is limited; the source of allogeneic bone and heterogeneo...

AI Technical Summary

Problems solved by technology

However, in the later animal experiments of this material, it was found that the dry laying-sintering method took a long time to manufacture the material, the operation was inconvenient, and the HA / ZrO prepared each time 2 The porosity of gradient composites is uncontrollable, and there is a floating range of about 100 μm

At the same time, the preparation of this method requires a fixed mold and a fixed finished product style, which cannot meet the requirements of clinical complex bone defects. Therefore, a way is needed to improve the preparation process and reflect the individual needs of biomaterial treatment.

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