Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A kind of intrauterine intrauterine object, preparation method and application thereof

A uterine cavity and object placement technology, which is applied in the field of preparation and animal-derived uterine cavity implants, can solve problems such as endometrial repair cannot be completed smoothly, menstrual flow does not increase significantly, uterine cavity re-adhesion, etc., to solve infertility problems, Effect of reducing scar formation, promoting growth and differentiation

Active Publication Date: 2018-08-31
BEIJING BIOSIS HEALING BIOLOGICAL TECH
View PDF1 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, intrauterine adhesions may still occur after TCRA, and once intrauterine adhesions recur, endometrial repair will not be completed smoothly, and the clinical manifestations are no significant increase in menstrual flow or amenorrhea, so it is still necessary to take Certain anti-adhesion measures

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A kind of intrauterine intrauterine object, preparation method and application thereof
  • A kind of intrauterine intrauterine object, preparation method and application thereof
  • A kind of intrauterine intrauterine object, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0068] Figure 9 It is a schematic diagram of a uterine intrauterine implant according to an embodiment of the present invention. The uterine intrauterine implant is a bag-like structure with a roughly trapezoidal shape and at least part of the corners are arc-shaped. The opening 2 is located on the side of the shorter base of the trapezoid. It can be made by using one piece of small intestine submucosa matrix material that has been freeze-dried in vacuum and then folded in half, or by using two or more pieces of matrix material. The uterine intrauterine implant can be placed in the uterine cavity and unfolded, so as to isolate and protect the wound surface, promote the recovery of uterine cavity basement membrane and mucosa and other tissues, and prevent the occurrence of adhesions.

[0069] Further, the intrauterine intrauterine implant in the above embodiment may also include a supporting structure, so that the intrauterine intrauterine implant can be stretched inside the ...

Embodiment approach 2

[0073] Figure 10 It is a schematic diagram of an intrauterine implant according to another mode of the present invention. The uterine intrauterine implant 1 is a bag-like structure with a roughly triangular shape and at least part of the corners are arc-shaped. The opening 2 is located on one side of the triangle, and the length of the opening 2 is smaller than the length of the side, so that each end of the IUD 3 can be clamped at the end of the roughly triangular bag-shaped structure 1 . In the process of placing the intrauterine intrauterine device of this embodiment, the IUD 3 can be placed in the inner cavity of the intrauterine intrauterine object 1 in advance, and placed in the IUD placement device 4 together. Then make the IUD placement device 4 pass through the uterine ostium, and then make the uterine cavity built-in part break away from the IUD placement device and enter the uterine cavity. The intrauterine intrauterine implant 1 and the intrauterine device 3 tog...

Embodiment approach 3

[0075] Figure 11 It is a schematic diagram of an intrauterine implant according to another mode of the present invention. The uterine cavity implant 1 is a bag-like structure, and its shape is roughly round or oval. The opening 2 is located on a round face or a round edge of a circle or an ellipse. The IUD 3 and the uterine intrauterine implant 1 can be placed in the uterine cavity by implementing the placement method of 1 or 2.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
diameteraaaaaaaaaa
lengthaaaaaaaaaa
heightaaaaaaaaaa
Login to View More

Abstract

Disclosed are a uterine cavity implant, a preparation method and the use thereof. The uterine cavity implant has a bag-shaped structure, and comprises a substrate material of an animal small intestine submucosa having been subjected to a decellularization treatment. The uterine cavity implant is prepared by subjecting the substrate material to tissue pre-processing, virus inactivation, washing, decellularization in a multi-frequency ultrasonic device, washing, vacuum freeze-drying, and a molding step. The uterine cavity implant is used in uterine cavity-implanted medical instruments, and can treat and prevent intrauterine adhesion, and improve the decellularization process for a biological repair material, so that the uterine cavity implant has a lower quantity of residual DNA, lower immunogenicity, stronger anti-infection capacity and stronger repair capacity; and same is beneficial for the recovery of tissues, such as the uterine cavity basal layer, submucosa and mucous layer. The uterine cavity implant, as a built-in uterine cavity structure, is used for isolating wound surfaces, repairing uterine cavity tissues and reducing scar formation, so that the problem of intrauterine adhesion is solved, and the problem of sterility caused by same can also be solved.

Description

technical field [0001] The invention relates to the technical field of medical biomaterials, in particular to an intrauterine implant of animal origin, a preparation method and use thereof. The intrauterine intrauterine implant is an animal-derived material, and is used for treating and preventing intrauterine adhesions. Background technique [0002] Endometrium refers to the layer that forms the lining of the mammalian uterus. The endometrium is divided into three layers: dense layer, spongy layer and basal layer. 2 / 3 of the surface of the inner membrane is dense layer and spongy layer, collectively referred to as the functional layer, which undergoes periodic changes and falls off under the influence of ovarian sex hormones. The basal layer is the 1 / 3 endometrium close to the myometrium, rich in blood vessels, unaffected by ovarian sex hormones, and does not undergo periodic changes. [0003] Clinically, when there is trauma on the inner wall of the uterus, such as uter...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/00A61L31/04A61L31/14
CPCA61L31/005A61L31/046A61L31/14C08L89/00
Inventor 赵博王洪权夏磊磊赵延瑞李学军张晋辉
Owner BEIJING BIOSIS HEALING BIOLOGICAL TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com