Unlock instant, AI-driven research and patent intelligence for your innovation.

Clothianidin Controlled-release Embedded Granules and Its Preparation and Application

A technology of clothianidin and granules, which is applied in the agricultural field and can solve the problems of no sustained-release performance and conventional granules that do not have sustained-release performance.

Active Publication Date: 2021-04-27
INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI
View PDF9 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The appearance is the same as conventional granules, but the carrier selected by conventional granules is a conventional filler (such as kaolin, clay, diatomaceous earth, calcium carbonate, etc.) without sustained-release performance, so that conventional granules do not have sustained-release performance

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Pour 8g of polycaprolactone polyol (melting point about 60°C) into a 25mL beaker, heat to a molten state, then add 4g of polyethylene glycol 4000, and heat on a heating magnetic stirrer until completely dissolved and transparent. After it is completely transparent, add 4g of clothianidin technical substance 97% into it and continue to heat and stir until clear and transparent, then add 4g of beeswax (melting point 62-67° C.) and continue to stir until translucent. Then cool, stirring continuously during the cooling process, after the temperature drops, pour it on the pre-prepared ziplock bag and spread it. After the cooling is complete, pulverize with a small universal pulverizer, collect powders smaller than 100 mesh, and obtain clothianidin controlled-release embedding granules.

[0027] After content detection, the drug loading capacity is 17.8%, and the embedding rate is 92%. The release simulation experiment was carried out in the medium (2.5% methanol pH7.0 buffe...

Embodiment 2

[0029] Example 2: Preparation of 19.4% Clothianidin Controlled-release Embedded Granules

[0030] Pour 7g of polycaprolactone polyol (melting point about 60°C) into a 25mL beaker, heat to a molten state, then add 4g of polyethylene glycol 4000, and heat on a heating magnetic stirrer until completely dissolved and transparent. After it is completely transparent, add 4g of clothianidin technical substance 97% to it and continue to heat and stir until it is clear and transparent, then add 5g of beeswax and continue to stir until it is translucent. Then cool, stirring continuously during the cooling process, after the temperature drops, pour it on the pre-prepared ziplock bag and spread it. After the cooling is complete, use a small universal pulverizer to pulverize and collect powder less than 100 mesh. Clothianidin controlled-release embedded granules were obtained.

[0031] After content detection, the drug loading capacity was 19.4%, and the embedding rate was 100%. The rel...

Embodiment 3

[0032] Example 3: Preparation of 17.9% Clothianidin Controlled Release Embedded Granules

[0033] Pour 4g of polyethylene glycol 4000 into a 25mL beaker, heat to a molten state, then add 12g of carnauba wax (melting point 80-86°C), and heat on a heating magnetic stirrer until completely dissolved and transparent. After being completely transparent, 4 g of clothianidin 97% technical substance was added therein and continued heating and stirring until clear and transparent. Then cool, stirring continuously during the cooling process, after the temperature drops, pour it on the pre-prepared ziplock bag and spread it. After the cooling is complete, use a small universal pulverizer to pulverize and collect powder less than 100 mesh. Clothianidin controlled-release embedded granules were obtained.

[0034] After content detection, the drug loading capacity was 17.9%, and the embedding rate was 92.3%. The release simulation experiment was carried out in the medium (2.5% methanol p...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a clothianidin controlled-release embedding granule, which is composed of clothianidin and a carrier, the carrier is a low melting point carrier, and the melting point of the carrier is 53-90°C; clothianidin accounts for the clothianidin 10.0-30.0% of the mass of the controlled-release embedded granules. The invention also proposes the preparation and application of the clothianidin controlled-release embedded granule. The controlled-release embedding granule proposed by the present invention is environmentally friendly, low in cost and easy for industrial production. It uses a low-melting, degradable organic compound as a carrier, and the carrier is in a molten state through proper heating, and the active ingredients of the pesticide are evenly dispersed. Or dissolved in a molten carrier, cooled naturally, mechanically pulverized and sieved to prepare controlled-release embedding granules. The preparation steps are simple, the active ingredient of the pesticide has a high embedding rate, and the effective ingredient of the pesticide is gradually released along with the degradation of the carrier, so that the effect of preventing and controlling pests and diseases can be more efficiently exerted.

Description

technical field [0001] The invention belongs to the field of agriculture, and in particular relates to a nicotinic pesticide clothianidin, its preparation and application. Background technique [0002] The effective utilization rate of conventional pesticide spraying is only 20% to 30%. Most of the active ingredients of pesticides are lost to the atmosphere, soil, water and other environments, which not only pollutes the environment, but also causes serious waste. Therefore, developing new pesticide formulations that are safe, environmentally friendly, long-lasting, and reduce environmental pollution is one of the future development directions of pesticide formulations. [0003] Controlled-release embedded granules are a new type of pesticide dosage form with slow-release performance. The low-melting point organic compound carrier is in a molten state by heating, and the active ingredients of the pesticide are mixed with the molten carrier or dissolved in the molten carrier....

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A01N25/26A01N51/00A01P7/04
CPCA01N25/26A01N51/00
Inventor 陈福良尹明明顺布尔
Owner INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI