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Self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition, and preparation method and applications thereof

A technology of Gynostemma pentaphyllum extract and Gynostemma pentaphyllum, applied in drug combination, capsule delivery, pharmaceutical formulation, etc., can solve the problems of excessive use risk, difficulty in applying insoluble ingredients to promote absorption, etc., and achieve the goal of improving drug efficacy and increasing extraction efficiency Effect

Active Publication Date: 2017-11-17
刘峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the self-emulsifying drug delivery system inevitably needs to add a large amount of surfactants, it brings certain safety risks to the administration, especially in the field of health food, the high risk of use makes it difficult to apply the self-emulsifying drug delivery system to health food Accelerated absorption of insoluble ingredients

Method used

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  • Self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition, and preparation method and applications thereof
  • Self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition, and preparation method and applications thereof
  • Self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition, and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 self-emulsifying propolis medlar gynostemma composition

[0032] 1. Extraction of propolis

[0033] Take the propolis block and crush it at low temperature. Mix 80% ethanol aqueous solution (volume percentage, the same below) with 10 times the mass of propolis and soybean vegetable oil with 0.1 times the mass of propolis as an extraction solvent. Carry out cold soaking extraction, extraction time is 72 hours. Remove the filter residue by filtration, and concentrate under reduced pressure at 40°C until the relative density is 1.2-1.3.

[0034] 2. Extraction of wolfberry

[0035]Take wolfberry, wash and chop. Mix 80% ethanol aqueous solution with 10 times the mass of wolfberry and soybean vegetable oil with 0.1 times the mass of wolfberry as the extraction solvent. Carry out heating reflux extraction, extraction time is 6 hours. The filter residue was removed by filtration, and the filtrate was concentrated under reduced pressure at 40°C to a relative d...

Embodiment 2

[0042] Embodiment 2 self-emulsifying propolis medlar gynostemma composition

[0043] The preparation of propolis extract, wolfberry extract and Gynostemma pentaphyllum extract is the same as in Example 1.

[0044] The above-mentioned propolis extract, wolfberry extract and Gynostemma pentaphyllum extract are uniformly mixed with soybean vegetable oil in a mass ratio of 0.1:0.1:0.1:0.1 to obtain the product.

Embodiment 3

[0045] Embodiment 3 self-emulsifying propolis medlar gynostemma composition

[0046] The preparation of propolis extract, wolfberry extract and Gynostemma pentaphyllum extract is the same as in Example 1.

[0047] Take the above propolis extract, wolfberry extract and Gynostemma pentaphyllum extract, and mix them evenly with soybean vegetable oil in a mass ratio of 1:0.1:0.1:0.1 to obtain the product.

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Abstract

The invention discloses a self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition, and a preparation method and applications thereof. The self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition comprises a propolis extract, a Chinese wolfberry extract, a gynostemma pentaphylla extract, and plant oil. According to the preparation method, the self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition is prepared via uniform mixing of the propolis extract, the Chinese wolfberry extract, the gynostemma pentaphylla extract, and plant oil. The self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition possesses self emulsifying function in contact with water, self emulsifying can be realized without adding extra surfactant, absorption and utilization of effective components in propolis, Chinese wolfberry, and gynostemma pentaphylla can be improved obviously. Application prospect of the self-emulsified propolis Chinese wolfberry gynostemma pentaphylla composition in preparation of drugs used for improving human immunity is promising.

Description

technical field [0001] The present invention relates to a self-emulsified propolis Lycium barbarum Gynostemma composition, and also relates to a preparation method of the composition. The present invention further relates to the application of the self-emulsified propolis Lycium barbarum Gynostemma composition in the preparation of medicines for improving human immunity, which belongs to self-emulsified The preparation and application field of the emulsified propolis medlar gynostemma composition. Background technique [0002] Propolis is a viscous substance secreted by Chinese bees of the family Apiaceae to repair the hive. It can be used as medicine. It is flat in nature, bitter, pungent and slightly sweet. Taken orally to nourish weakness, remove turbid fat, relieve thirst, and be used for frailty and premature aging, hyperlipidemia, diabetes, etc. [0003] Lycium barbarum is a precious Chinese herbal medicine and tonic, flat in nature and sweet in taste. It has the eff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/48A61P37/04A61K35/644
CPCA61K9/4841A61K35/644A61K36/424A61K36/815A61K2236/333A61K2236/35A61K2236/51A61K2300/00
Inventor 刘峰车鑫张欣
Owner 刘峰