Composite nanometer antibacterial agent having bacterium specific recognition capacity and application of composite nanometer antibacterial agent

Abstract

The invention discloses a composite nanometer antibacterial agent having a bacterium specific recognition capacity and an application of the composite nanometer antibacterial agent, and belongs to the technical field of high-molecular polymers. The composite nanometer antibacterial agent consists of silver nanoparticles, boron fluoride dipyrrole molecules and polygalactose, wherein the silver nanoparticles constitute silver nanospheres; the polygalactose is represented in the form of polygalactose chains; the silver nanospheres are connected to one end of each of the plurality of polygalactose chains; one of the boron fluoride dipyrrole molecules is connected to the other end of each polygalactose chain; and all boron fluoride dipyrrole molecules surround the silver nanospheres, so that a sphere-like structure is also formed. The composite nanometer antibacterial agent particle prepared by the invention has a selective recognition capacity on pseudomonas aeruginosa, escherichia coli, clostridium tetani and staphylococcus aureus, and the particle is not or is least adsorbed by normal human cells; therefore, on the basis of causing relatively low toxic and side effects to human body, an antibacterial purpose can be selectively achieved.

Description

technical field [0001] The invention relates to a composite nano antibacterial agent, which belongs to the technical field of high molecular polymers, in particular to a composite nano antibacterial agent with bacteria-specific recognition ability and its application. Background technique [0002] The variety and rapid variation of pathogenic microorganisms make antibacterial therapy always face great challenges. Although antibiotics have a clear therapeutic effect on many pathogenic microorganisms, in the game between antibiotics and pathogenic microorganisms, antibiotics no longer have an overwhelming advantage. The incidence is increasing. Although people are still doing their best to develop new antibiotics, their research and development speed lags far behind the mutation speed of pathogenic microorganisms; what is more serious is that the problem of drug resistance has not been solved at all, but it is getting more and more serious, and several kinds of antibiotics ha...

AI Technical Summary

Problems solved by technology

Although antibiotics have a clear therapeutic effect on many pathogenic microorganisms, in the game between antibiotics and pathogenic microorganisms, antibiotics no longer have an overwhelming advantage. increasing incidence

Although people are still doing their best to develop new antibiotics, their research and development speed lags far behind the mutation speed of pathogenic microorganisms; what is more serious is that the problem of drug resistance has not been solved at all, but it is getting more and more serious, and several kinds of antibiotics have appeared. Drug-resistant "super bacteria" have caused alarm and even panic around the world

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