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Calcium alginate biological composite medical dressing and preparation method thereof

A calcium alginate and calcium alginate fiber technology, applied in dressings, adhesive dressings, non-adhesive dressings, etc., can solve the problems of losing antibacterial function, increasing material cost, easy peeling, etc., to achieve resistance to traction and mechanical stimulation, The effect of reducing mechanical damage and simple preparation process

Inactive Publication Date: 2017-12-15
HANGZHOU INST OF ADVANCED MATERIAL BEIJING UNIV OF CHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when there is too much effusion, the ordinary alginate dressing is easily soaked, thus losing its antibacterial function, and it is easy to peel off and collapse with the movement of the skin
In general clinical use, the amount of alginate dressing used and the frequency of replacement will be increased to solve the problem of excessive effusion, but this not only increases the material cost, but also increases the labor cost, which is not conducive to quick and effective wound treatment

Method used

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  • Calcium alginate biological composite medical dressing and preparation method thereof
  • Calcium alginate biological composite medical dressing and preparation method thereof
  • Calcium alginate biological composite medical dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A calcium alginate biocomposite medical dressing, comprising a non-woven fabric layer and a composite dressing functional layer material,

[0031] Non-woven fabric layer material: viscose fiber, length 30mm;

[0032] Composite dressing functional layer material: the content of calcium alginate fiber is 90%, and the content of functional chitosan fiber is 10%; the length of the calcium alginate fiber is 30mm, and the linear density is 2dtex;

[0033] The functional chitosan fiber is prepared by the following method: take 100 parts of deionized water, add 1 part of nano silver oxide and 2 parts of sodium pyrophosphate under stirring in a high-shear mixer, quickly stir and disperse evenly, slowly add 3 parts of carboxylate Sodium methyl cellulose and 1 part of hyaluronic acid, continue to stir until a uniform semi-viscous liquid is obtained, then 50 parts of chitosan fiber are immersed in the semi-viscous liquid, stirred slowly, and then dehydrated and dried under low pressure. ...

Embodiment 2

[0040] A calcium alginate biocomposite medical dressing, comprising a non-woven fabric layer and a composite dressing functional layer material,

[0041] Non-woven fabric layer material: acetate fiber, 45mm in length;

[0042] Composite dressing functional layer material: the content of calcium alginate fiber is 80%, the content of functional chitosan fiber is 20%; the length of the calcium alginate fiber is 30mm, and the linear density is 3dtex;

[0043] Functional chitosan fiber is prepared by the following method: take 100 parts of deionized water, add 2 parts of nano zinc oxide and 5 parts of sodium pyrophosphate under stirring in a high-shear mixer, quickly stir and disperse evenly, slowly add 4 parts of carboxylate Sodium methylcellulose and 4 parts of hyaluronic acid, continue to stir until a uniform semi-viscous liquid is obtained, then 45 parts of chitosan fibers are dipped in the semi-viscous liquid, slowly stirred, dehydrated and dried under low pressure. Functional chito...

Embodiment 3

[0050] A calcium alginate biocomposite medical dressing, comprising a non-woven fabric layer and a composite dressing functional layer material,

[0051] Non-woven fabric layer material: polyvinyl alcohol fiber, length 60mm;

[0052] Composite dressing functional layer material: the content of calcium alginate fiber is 70%, and the content of functional chitosan fiber is 30%; the length of the calcium alginate fiber is 30mm, and the linear density is 4dtex;

[0053] The functional chitosan fiber is prepared by the following method: take 100 parts of deionized water, add 3 parts of nano silver oxide and 4 parts of sodium pyrophosphate under stirring in a high-shear mixer, stir quickly and evenly disperse, slowly add 6 parts of carboxylate Sodium methyl cellulose and 3 parts of hyaluronic acid, continue to stir until a uniform semi-viscous liquid is obtained, then 30 parts of chitosan fibers are immersed in the semi-viscous liquid, stirred slowly, and then dehydrated and dried under lo...

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Abstract

The invention belongs to the technical field of a biological medical dressing, and particularly relates to a calcium alginate biological composite medical dressing and a preparation method thereof. The calcium alginate biological composite medical dressing comprises a nonwoven fabric layer and a composite dressing functional layer, and is characterized in that the composite dressing functional layer covers the nonwoven fabric layer; the composite dressing functional layer consists of calcium alginate fiber and functional chitosan fiber. The preparation method comprises the following steps of (1) preparing the nonwoven fabric layer; (2) preparing the composite dressing functional layer; (3) puncturing the nonwoven fabric layer and the composite dressing functional layer by a needle; (4) performing cutting, packaging, sterilization and warehouse entering on the biological composite dressing. The dressing can be used for treating various kinds of skin injury such as operation wound, burn and scald wound surfaces and the like; the effects of hemostasis, hemoglutination, bacteriostasis, inflammation diminishing and wound healing promotion are achieved; in addition, the strong force of the alga fiber strong force is improved; the production process is simple; green and environment-friendly effects are achieved; the cost is low.

Description

Technical field [0001] The invention belongs to the technical field of biomedical dressings, and specifically relates to a calcium alginate biocomposite medical dressing and a preparation method thereof. Background technique [0002] With the development of society, clinical and war injury treatment have higher and higher requirements for local trauma hemostasis. Biomedical materials are considered to be one of the most effective materials for local trauma hemostatic dressings. They have the advantages of absorbability, high efficiency, economy and non-toxicity. Biomedical materials are a new type of hemostatic materials, which are mainly based on their own material characteristics and advantages. It absorbs blood, aggregates platelets, blocks blood vessels, promotes the production of thrombin, and achieves hemostasis. [0003] Medical dressings are used as wound coverings, which can replace damaged skin to act as a temporary barrier during wound healing, avoid or control wound in...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/18A61L15/42A61L15/44A61L15/46D04H1/4258D04H1/435D04H1/4358D04H1/4374D04H1/4382D04H1/46A61F13/02
CPCA61L15/18A61L15/28A61L15/42A61L15/44A61L15/46A61F13/0206A61F13/0276D04H1/4258D04H1/435D04H1/4358D04H1/4374D04H1/4382D04H1/46A61L2300/102A61L2300/104A61L2300/404A61L2300/418A61F2013/00089A61F13/01008A61F13/01029C08L5/08C08L5/04C08L1/286
Inventor 马贵平许艳婷陈广凯聂俊
Owner HANGZHOU INST OF ADVANCED MATERIAL BEIJING UNIV OF CHEM TECH
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