Toothpaste with functions of resisting helicobacter pylori in oral cavity, preventing caries and invigorating stomach and preparation method of toothpaste

Abstract

The invention provides an oral toothpaste with anti-helicobacter pylori and anti-caries and stomach-enhancing functions. The toothpaste contains bismuth glycyrrhizinate at a concentration of 0.001% to 10% by weight. Bismuth Glycyrrhizinate combines the anti-inflammatory, analgesic, anti-ulcer, anti-oxidation effects of glycyrrhizic acid and the gastric mucosal protection function of bismuth. The bismuth glycyrrhizinate toothpaste of the present invention is a kind of daily oral hygiene article, practical and convenient, multi-effect of one product, can effectively kill HP and cariogenic bacteria, simultaneously bismuth glycyrrhizinate is dental plaque inhibitory and cleaning agent, thereby helps to inhibit and remove dental plaque, reduce the chance of bacterial adhesion and aggregation, and treat both symptoms and root causes; making it into toothpaste for external use can effectively, conveniently and durably kill Helicobacter pylori in the oral cavity, thereby effectively preventing gastrointestinal The purpose of treating tract infection and preventing the recurrence of gastritis, gastric and duodenal ulcers.

Description

technical field [0001] The invention relates to the field of oral health care products, in particular to a toothpaste with the functions of anti-helicobacter pylori, anti-caries and invigorating the stomach and a preparation method thereof. Background technique [0002] In 1983, Australian scholars Warren and Marshall isolated Helicobacter pylori (HP) for the first time from the gastric antrum mucus layer and epithelial cells of patients with chronic gastritis. In 1989, Australian scholar Krajden detected HP from the dental plaque of the oral teeth of patients with gastritis. From the molecular level, it is confirmed that it is the same as HP in the stomach. In 1994, WHO listed HP infection as a new infectious disease, and domestic and foreign literature reported that HP is an oral-transmitted infectious disease. Oral HP is an important reservoir of gastric HP infection. According to epidemiological investigations, the infection rate of HP among teenagers under the age of ...

AI Technical Summary

Problems solved by technology

The existing technology uses large doses of multiple antibiotics to kill Helicobacter pylori at the same time, which increases the drug resistance of Helicobacter pylori, easily leads to repeated attacks of the disease, and increases the difficulty of treatment

The disadvantage of the prior art is that taking large doses of antibiotics makes Helicobacter pylori resistant

Antibiotics are an effective means for humans to fight against bacterial infections. Bacterial drug resistance reduces or loses the therapeutic effect of originally effective antibiotics, increasing the difficulty of treatment and medical costs for patients

[0004] Toothpaste is an oral hygiene product that everyone must use every day. The existing toothpaste with bactericidal function, some add antibiotics and disinfectants, such as triclosan, chlorhexidine, etc., to kill all harmful and beneficial bacteria. Destroys the oral micro-ecological environment and increases bacterial resistance

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