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Pharmaceutical composition for effectively treating premature ejaculation and repairing chronic strain of penises

An effective treatment and premature ejaculation technology, applied in the field of medicine, can solve the problems of low patient acceptance and compliance, inability to serve patients, and unsatisfactory curative effect, and achieve the goal of reducing skin sensitivity, reducing local sensitivity, and preventing dry and cracked skin. Effect

Inactive Publication Date: 2017-12-29
梅军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For secondary premature ejaculation, the problem does not involve a general medical disorder, and it usually does not involve substance induction, however, hyperarousal may involve psychotropic drug use in specific cases and subsides when the drug is withdrawn
[0004] The technical methods currently on the market for the treatment of premature ejaculation are mainly surgery (cutting off part of the dorsal nerve branch of the penis), external application (local anesthetics), oral administration (serotonin reuptake inhibitors), etc. , or the cycle is long, or the cost is high, and the curative effect is not ideal, the patient's acceptance and compliance are low, and it cannot really serve the majority of patients effectively

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] This example provides a drug combination for effectively treating premature ejaculation and repairing chronic strain of the penis: TMSD Repairing Jiangsensitivity Injection, the raw material components include:

[0041] Water for injection, 90 parts by weight;

[0042] Sodium hyaluronate, 2.5 parts by weight,

[0043] Methylene blue, 0.01 parts by weight;

[0044] Ceramide, 1.5 parts by weight;

[0045] Sodium paeonol sulfonate, 0.01 parts by weight.

[0046] Further, the present invention provides a method for preparing the drug combination for effectively treating premature ejaculation and repairing chronic strain of the penis, comprising the following steps:

[0047] (1) Take 9 / 10 of the water for injection and heat it to 30°C, then add methylene blue and sodium paeonol sulfonate in turn, and stir until completely dissolved;

[0048] (2) Add sodium hyaluronate to the solution obtained in step (1), stir and heat to 75°C to form a uniform gel, and place it at room ...

Embodiment 2

[0051] This example provides a drug combination for effectively treating premature ejaculation and repairing chronic strain of the penis: TMSD Repairing Jiangsensitivity Injection, the raw material components include:

[0052] Water for injection, 98 parts by weight;

[0053] Sodium hyaluronate, 0.01 parts by weight,

[0054] Methylene blue, 1 part by weight;

[0055] Ceramide, 0.01 parts by weight;

[0056] Sodium paeonol sulfonate, 5 parts by weight.

[0057] Further, the present invention provides a method for preparing the drug combination for effectively treating premature ejaculation and repairing chronic strain of the penis, comprising the following steps:

[0058] (1) Take 7 / 10 of the water for injection and heat it to 40°C, then add methylene blue and sodium paeonol sulfonate in turn, and stir until completely dissolved;

[0059] (2) Add sodium hyaluronate to the solution obtained in step (1), stir and heat to 85°C to form a uniform gel, and place it at room tempe...

Embodiment 3

[0062] This example provides a drug combination for effectively treating premature ejaculation and repairing chronic strain of the penis: TMSD Repairing Jiangsensitivity Injection, the raw material components include:

[0063] Water for injection, 97 parts by weight;

[0064] Sodium hyaluronate, 1.2 parts by weight,

[0065] Methylene blue, 0.15 parts by weight;

[0066] Ceramide, 0.5 parts by weight;

[0067] Sodium paeonol sulfonate, 0.8 parts by weight.

[0068]Further, the present invention provides a method for preparing the drug combination for effectively treating premature ejaculation and repairing chronic strain of the penis, comprising the following steps:

[0069] (1) Take 4 / 5 of the water for injection and heat it to 35°C, then add methylene blue and sodium paeonol sulfonate in turn, and stir until completely dissolved;

[0070] (2) Add sodium hyaluronate to the solution obtained in step (1), stir and heat to 80°C to form a uniform gel, and place it at room tem...

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PUM

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Abstract

The invention relates to pharmaceutical composition for effectively treating premature ejaculation and repairing chronic strain of penises and a preparation method of the pharmaceutical composition. The pharmaceutical composition is prepared from sodium hyaluronate, methylene blue, ceramide and sodium paeonolsilate as raw materials in a proper weight ratio. The prepared pharmaceutical composition has stable physical and chemical properties and has a synergistic effect on reducing sensitivity of penile skin and repairing trauma caused by frequent stretching of the penises. The pharmaceutical composition has the advantages of small treatment trauma, high safety, good treatment effect and quick curative effect. During treatment, the pharmaceutical composition is delivered through subcutaneous injection or with an ultrasonic transdermal technology to specific subcutaneous parts such as an inner plate, within 2 cm from the coronary sulcus, of the penile ventral midline of the frenum, purposes of reducing penile sensitivity, repairing chronic strain of the penises and the like are achieved, the treatment process is simple to operate, and the pharmaceutical composition is accepted by patients easily.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a medicine combination for effectively treating premature ejaculation and repairing chronic strain of the penis and a preparation method thereof. Background technique [0002] Premature ejaculation (PE) is a common sexual dysfunction in men, especially those aged 18-40 years. Premature ejaculation can generally be defined as ejaculation occurring before or sooner than expected by one or both sexual partners. For example, premature ejaculation can be ejaculation experienced before, while, or immediately after penetration of the penis into a sexual partner. If instances of premature ejaculation are rare and distant, such occurrences may not be cause for concern. However, if premature ejaculation occurs virtually every time sexual intercourse is attempted, or if premature ejaculation occurs greater than about 10% or about 20% of the time sexual intercourse is attempt...

Claims

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Application Information

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IPC IPC(8): A61K31/728A61K31/5415A61K31/164A61K31/185A61K9/08A61P15/10A61P15/00
CPCA61K9/0009A61K9/0019A61K9/08A61K31/164A61K31/185A61K31/5415A61K31/728A61K2300/00
Inventor 梅军
Owner 梅军
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