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Preparation method of medicine for treating acute and sub-acute eczema

A subacute and eczema technology, applied in the field of film coating preparation, can solve the problems of bacterial infection, difficult to cure, etc., and achieve the effects of strong adhesion, long-lasting efficacy, and increased skin and limb penetration.

Inactive Publication Date: 2018-02-06
CHENGDU SHENGSHI GUANGHUA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many clinical treatments are still difficult to cure
At present, symptomatic treatment is mostly used clinically, and there are bacterial infections that cannot be ignored in the treatment, especially the lesion site has affinity for Staphylococcus aureus

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A preparation method for treating acute and subacute eczema of the present embodiment comprises the following steps:

[0022] (1) Add 20g of loratadine and 10g of neomycin sulfate into 250g of ethanol, stir to dissolve, and obtain a mixed solution for use;

[0023] (2) Sprinkle 4g ​​of chitosan evenly to make it swell naturally;

[0024] (3) Add 1.0g arbutin, stir constantly, and add ethanol to 1000mL;

[0025] (4) Adjust the pH to 6.0~7.0, stir well, and then it can be used as a medicine for treating acute and subacute eczema.

[0026] The specific implementation process is to clean the affected area, apply the prepared medicine for treating acute and subacute eczema evenly on the surface of the affected area, and after it dries naturally, a gel-like film with a thickness of 1 to 3 mm will be formed. After 3 to 5 hours, the film After the drug administration is completed, tear it off from the surface of the affected area, apply new drugs, 1-2 times a day, whether to ...

Embodiment 2

[0028] In this embodiment, on the basis of the above embodiments, the stirring process of the step (1) is further defined, which is mainly completed by a magnetic stirrer. The magnetic stirrer utilizes the characteristic of homosexual repulsion of magnetic substances to drive the magnetic stirrer to rotate by constantly changing the polarity of the two ends of the base, and the rotation of the magnetic stirrer drives the sample to rotate, so that the medicine is evenly mixed; the magnetic stirrer adopts high-quality DC The motor has low noise and stable speed regulation; the fully enclosed heating plate can be used for auxiliary heating and can be used for long-term heating; the stirring bar made of PTFE and high-quality magnetic steel is resistant to high temperature, wear and chemical Corrosion and strong magnetism; it can be mixed in a closed container, which is ideal and convenient to use; the temperature and temperature display of the agitator can be set and used for long-...

Embodiment 3

[0030] In this embodiment, on the basis of the above embodiments, the mixing container for the mixed solution in the step (3) is further defined as a 1200ml large beaker. Other steps in this embodiment are the same as those in the above embodiment, and will not be repeated here.

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Abstract

The invention discloses a preparation method for treating acute and subacute eczema, which comprises the following steps: 1) taking 20g of loratadine and 10g of neomycin sulfate and adding them to 250g of ethanol, stirring and dissolving to obtain a mixed solution for use ; 2) Sprinkle 4g ​​chitosan evenly to make it swell naturally; 3) Add 1.0g arbutin, keep stirring, and add ethanol to 1000mL; 4) Adjust the pH to 6.0~7.0, stir well, that is It can be used to treat acute and subacute eczema. In the present invention, loratadine and neomycin sulfate have obvious effects on inhibiting bacteria, and loratadine and neomycin sulfate are prepared into medicines. Due to the laurocapram transdermal technology, the penetration of the skin and limbs of the medicine is increased. , showing the superior curative effect of the coating agent on chronic eczema; the medicine for treating acute and subacute eczema made of chitosan has no greasy feeling, is easy to spread, has strong adhesion, and has a certain tear resistance. Convenient and non-irritating to the skin.

Description

technical field [0001] The invention relates to the field of preparation of coating agents, in particular to a method for preparing medicines for treating acute and subacute eczema. Background technique [0002] Eczema is a skin inflammatory reaction caused by complex internal and external factors. Chronic eczema is generally limited and has infiltration and hypertrophy, severe itching, and easy recurrence. The etiology of the disease is complex, and internal and external factors interact, often in many ways. Patients often have allergic constitution, which is related to genetic factors, so it occurs in specific groups of people. [0003] Acute eczema is an inflammatory skin disease of the epidermis and superficial dermis caused by a variety of internal and external factors. It has a variety of rashes and exudation tendencies, accompanied by severe itching, and is prone to repeated attacks. It is often related to allergic reactions. In the early or acute stage, the clinic...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K47/36A61K31/4545A61K31/7036A61K31/7034A61P17/00
CPCA61K9/7007A61K31/4545A61K31/7034A61K31/7036A61K47/36A61K2300/00
Inventor 张蛟
Owner CHENGDU SHENGSHI GUANGHUA BIOTECH CO LTD
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