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Preparation for treating haemophilia caused by Qi and blood deficiency and von Willebrand disease and method

A technology for qi and blood deficiency and hemophilia, which is applied in cardiovascular system diseases, blood diseases, medical preparations containing active ingredients, etc. The effect of improving bioavailability, absorption, and dissolution

Inactive Publication Date: 2018-02-16
天津市善济宏兴科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many types of drugs currently used clinically to treat hemophilia and von Willebrand disease, there are many factors that cause hemophilia and von Willebrand disease, and hemophilia and von Willebrand disease There are also many types of hemophilia, so these drugs are not targeted, the course of treatment is relatively long, and some drugs have certain side effects or allergic reactions, so after taking it, it is very important for the treatment of hemophilia and vascular pseudosomnia caused by both qi and blood deficiency. Not ideal for a disease like hemophilia

Method used

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  • Preparation for treating haemophilia caused by Qi and blood deficiency and von Willebrand disease and method
  • Preparation for treating haemophilia caused by Qi and blood deficiency and von Willebrand disease and method
  • Preparation for treating haemophilia caused by Qi and blood deficiency and von Willebrand disease and method

Examples

Experimental program
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Effect test

Embodiment 1

[0016] In this embodiment, the traditional Chinese medicine compound preparation for treating hemophilia and von Willebrand disease caused by both qi and blood deficiency is made from the following raw materials in dosages by weight:

[0017]

[0018] The preparation method of the traditional Chinese medicine compound preparation for treating hemophilia and von Willebrand disease caused by both deficiency of Qi and blood is carried out in the following sequence of steps:

[0019] (a) Weigh and mix the drug materials other than donkey-hide gelatin in the above-mentioned drug materials according to the proportion, then add water to soak for 25 minutes, then decoct for 30 minutes, and filter to remove the residue;

[0020] (b) Crush the donkey-hide gelatin into small pieces or powder, add a little rice wine, and steam until it melts;

[0021] (c) The clear liquid obtained in step (a) and the donkey-hide gelatin solution obtained in step (b) are mixed uniformly to prepare the described Chi...

Embodiment 2

[0024] In this embodiment, the traditional Chinese medicine compound preparation for treating hemophilia and von Willebrand disease caused by both qi and blood deficiency is made from the following raw materials in dosages by weight:

[0025]

[0026] The preparation method is the same as in Example 1.

Embodiment 3

[0028] In this embodiment, the traditional Chinese medicine compound preparation for treating hemophilia and von Willebrand disease caused by both qi and blood deficiency is made from the following raw materials in dosages by weight:

[0029]

[0030] The preparation method is the same as in Example 1.

[0031] The traditional Chinese medicine compound preparation for treating hemophilia and von Willebrand disease caused by both deficiency of qi and blood provided by the present invention is brown to tan; the gas is weak and the taste is slightly bitter. In order to verify the therapeutic effect of the traditional Chinese medicine compound preparation, the present inventors conducted systematic clinical observations on 332 patients with qi and blood deficiency hemophilia and von Willebrand disease using the above-mentioned Chinese medicine compound preparation, among which 21-30 There were 91 patients aged 31-40 years old, 127 patients aged 31-40 years old, 114 patients aged 41-50 ...

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Abstract

A preparation for treating haemophilia caused by Qi and blood deficiency and von Willebrand disease and a method. The preparation is produced from, by weight, 18-48 parts of raw astragalus membranaceus, 6-15 parts of codonopsis pilosula, 9-24 parts of raw atractylodes macrocephala, 9-24 parts of poria cocos, 6-15 parts of pericarpium citri reticulatae, 6-15 parts of angelica sinensis, 6-15 parts of colla corii asini, 6-15 parts of Chinese wolfberries, 6-15 parts of fructus psoraleae, 6-15 parts of pomegranate peel, 9-24 parts of Chinese dates, and 4-10 parts of honey-fried licorice roots. In the invention, active components in the raw material medicines are extracted in a manner of water boiling, wherein the activities are maintained, so that in the preparation, the dissolution rates of the active components are greatly increased, and the medicines are easy to absorb, thus increasing the bioavailability of the preparation; in addition, the preparation is a pure-traditional Chinese medicine compound preparation, so that no toxic and side effect is generated after long time use by a patient, and the preparation is good in safety. The preparation method is simple and is convenient tocarry out.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a traditional Chinese medicine compound preparation and preparation method thereof for treating hemophilia and von Willebrand disease caused by qi and blood loss method. Background technique [0002] Hemophilia is an inherited bleeding disorder. The common feature is the disorder of active thrombin generation, long clotting time, and severe bleeding can be caused by patients with mild trauma. Von Willebrand disease is a bleeding disorder characterized by prolonged bleeding time, lack of plasma antihemophilic globulin, and decreased platelet adhesion. Although there are many types of drugs used in clinical treatment of hemophilia and von Willebrand disease, there are many factors that cause hemophilia and von Willebrand disease, and hemophilia and von Willebrand disease There are also many types of friend diseases. Therefore, these drugs ...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P7/04A61P9/14A61K35/36
CPCA61K35/36A61K36/076A61K36/185A61K36/232A61K36/284A61K36/344A61K36/481A61K36/484A61K36/487A61K36/725A61K36/752A61K36/815A61K2236/331A61K2300/00
Inventor 马力王维蔚齐燕松
Owner 天津市善济宏兴科技发展有限公司
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