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Alginate-hydrogel cold compress patch and preparing method thereof

A technology of alginate and hydrogel, which is applied to cooling appliances for treatment, heating appliances for treatment, contraceptives, etc., to achieve the effects of prolonged cold compress effect, easy peeling, and guaranteed curative effect

Inactive Publication Date: 2018-04-13
GUANGDONG TAIBAO MEDICAL SCI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the prior art, there are a large number of reports about alginate hydrogel preparation technology, and there are also a large number of reports about hydrogel cold compresses, but there are few reports about alginate hydrogel cold compresses. Salt hydrogels are a relatively new field for cold compresses on painful wounds

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An alginate hydrogel cold compress, which is composed of the following raw materials in parts by weight: 10 parts of alginate aqueous solution, 5 parts of crosslinking agent, 0.5 part of cold storage agent, 1 part of guar gum, 0.5 part of glycerin, and 0.5 part of propylene glycol , 0.6 parts of glycerol, 0.1, 0.01, 0.5, 0.4 parts of lavender oil.

[0023] The preparation method of the alginate hydrogel cold compress is prepared by the following process steps: (1) Preparation of the reaction solution: stirring and dissolving sodium alginate in purified water to form a solution with a mass fraction of 0.1-10% , then add glycerin, guar gum, propylene glycol, fully stir and mix uniformly to form a mixed solution A; stir the crosslinking agent carboxymethyl chitosan calcium, glycerin, cold storage agent and lavender oil to fully stir and mix uniformly to form a mixed solution B . (2) Pre-crosslinking: Add the above mixed solution B into the mixed solution A and stir for 60...

Embodiment 2

[0026] An alginate hydrogel cold compress, which is composed of the following raw materials in parts by weight: 100 parts of alginate aqueous solution, 0.1 part of crosslinking agent, 2 parts of cold storage agent, 0.5 part of guar gum, 5 parts of glycerin, and 0.8 part of propylene glycol , 0.5 part of glycerin, 0.01 part of lavender oil.

[0027] The preparation method of the alginate hydrogel cold compress is prepared by the following process steps: (1) Preparation of the reaction solution: stirring and dissolving potassium alginate in purified water to form a solution with a mass fraction of 0.1-10% , then add glycerin, guar gum, propylene glycol, fully stir and mix uniformly to form a mixed solution A; stir the crosslinking agent carboxymethyl chitosan zinc, glycerin, cold storage agent and rose oil to fully stir and mix uniformly to form a mixed solution B . (2) Pre-crosslinking: Add the above mixed solution B into the mixed solution A and stir for 60 minutes to 180 min...

Embodiment 3

[0030] An alginate hydrogel cold compress, which is composed of the following raw materials in parts by weight: 50 parts of alginate aqueous solution, 0.8 parts of crosslinking agent, 1 part of cold storage agent, 0.1 part of guar gum, 3 parts of glycerin, and 0.6 parts of propylene glycol , 1 part of glycerin, 0.5 part of lavender oil.

[0031]The preparation method of the alginate hydrogel cold compress is prepared by the following process steps: (1) Preparation of the reaction solution: stirring and dissolving ammonium alginate in purified water to form a solution with a mass fraction of 0.1-10% , then add glycerin, guar gum, propylene glycol, fully stir and mix uniformly to form a mixed solution A; stir the cross-linking agent carmellose calcium, glycerol, cooling agent and neroli oil, fully stir and mix uniformly to form a mixed solution B . (2) Pre-crosslinking: Add the above mixed solution B into the mixed solution A and stir for 60 minutes to 180 minutes to form a pri...

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Abstract

The invention relates to the technical field of medical consumables, and discloses an alginate-hydrogel cold compress patch and a preparing method thereof. The alginate-hydrogel cold compress patch isprepared from, by weight, 10-100 parts of an alginate water solution, 0.1-5 parts of a cross-linking agent, 0.5-2 parts of a cool storage agent, 0.1-1 part of a thickening agent, 0.5-5 parts of a moisturizing agent, 0.5-1 part of an anti-freezing agent, 0.5-1 part of a blending agent and 0.01-0.5 part of cool and comfortable essential oil, and is prepared in the mode that the materials are subjected to a controllable cross-linking reaction. The technology for preparing the alginate-hydrogel cold compress patch is simple, the gel strength is suitable, the cold-compress curative effect durationtime is long, and the alginate-hydrogel cold compress patch is an ideal cold-compress patch product and suitable for large-scale application and production.

Description

technical field [0001] The invention relates to the technical field of medical consumables, and specifically includes an alginate hydrogel cold compress and a preparation method thereof. Background technique [0002] Hydrogels are gels in which water is the dispersion medium. Medical hydrogel is developed based on the theory of "moist therapy" for wound care. It has the characteristics of large drug loading, good transdermal effect, controllable quality, good air permeability, and low skin irritation, making it an ideal transdermal gel. drug delivery vehicle. The hydrogel cold compress is a gel that is attached to the skin. The temperature of the skin on the body surface is transmitted to the cold gel, and the heat is absorbed by the water molecules in the gel. A large amount of heat is taken away by the evaporation of water, which can quickly lower the body surface. The local temperature of the skin can reduce the burning sensation, pain and sensitivity of the local skin,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F7/02C08B31/00
CPCA61F7/02A61F7/0241A61F2007/0219A61F2007/0263C08B31/003
Inventor 陈锦涛韦加娜熊亮
Owner GUANGDONG TAIBAO MEDICAL SCI TECH
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