Balsam capable of removing prickly heat and relieving itching for infants as well as preparation method and application of balsam

A technology for removing prickly heat for infants and young children, which is applied in the field of daily chemical industry. It can solve the problems of easy volatilization, short action time and long effect time of peanut extract, so as to improve utilization rate and stability, not easy to store and add, and prolong use the effect of time

Active Publication Date: 2018-04-20

广州潮徽生物科技有限公司 +1

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Problems solved by technology

[0004] At present, consumers mostly choose care products whose main ingredients are natural plant extracts for infants and young children. Chinese patent CN201310267797.7 discloses a mosquito repellent and antipruritic toilet water. Various plant extracts such as eucalyptus oil, peppermint, and wild chrysanthemum have dual effects of repelling mosquitoes and relieving itching, and the effect lasts for a long time, but their complex components and high extraction costs are not conducive to popularization and application

Chinese patent CN201610680829.X discloses a prickly heat water for infants and young children containing peanut extract. The main component is peanut extract. The raw material is simple and easy to obtain, mild and non-irritating. It needs to be applied repeatedly, and it is easy to oxidize and deteriorate during long-term storage, which will affect the use effect

The patent literature of Chinese patent CN201410227445.3 discloses a prickly heat powder, wh...

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Abstract

The invention discloses balsam capable of removing prickly heat and relieving itching for infants as well as a preparation method and application of the balsam. The preparation method is characterizedby comprising the following steps: preparing flos chrysanthemi indici volatile oil ointment; refining the flos chrysanthemi indici volatile oil ointment to obtain flos chrysanthemi indici volatile oil; preparing a flos chrysanthemi indici volatile oil microcapsule by taking the flos chrysanthemi indici volatile oil as a core material; then preparing the balsam capable of removing prickly heat andrelieving itching for the infants by taking the flos chrysanthemi indici volatile oil microcapsule as a main efficacy component. According to the preparation method and the application of the balsamdisclosed by the invention, by microencapsulating the flos chrysanthemi indici volatile oil, the core material gradually permeates through the semipermeable capsule wall and volatilizes, the use timeof the core material is prolonged, the problem that plant essential oil is easy to volatilize is solved and the utilization rate and the stability of the plant essential oil can be improved. When thebalsam acts on the skin of an infant, effective ingredients can be released for a long time, and a continuous protective effect is achieved; without repeated smearing, resistance of the infant generated in the repeated smearing process is reduced. The balsam has the advantages of mildness, no irritation, no addition of extra essence and suitability for the delicate skins of the infants.

Application Domain

Cosmetic preparationsToilet preparations +4

Technology Topic

IrritationEssence oil +6

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Examples

Experimental program(5)

Example Embodiment

[0055] Example 1

[0056] Preparation of antidiarrheal and antipruritic balm for infants and young children:

[0057] (1) Preparation of wild chrysanthemum volatile oil ointment: the wild chrysanthemum is washed, dried, and crushed through an 80-mesh sieve to obtain wild chrysanthemum powder. Put the wild chrysanthemum powder in the extraction kettle, add subcritical fluid dimethyl ether (DME) according to the ratio of material to liquid of 1:8 (g:mL), extraction temperature is 20℃, extraction pressure is 0.5MPa, extraction is 4.5 h Obtain the subcritical initial extract of wild chrysanthemum, the solvent is recovered to the solvent tank by the circulating compressor, recycled, and extracted 3 times, and then the initial extracts obtained 3 times are combined. Finally, the initial extract was spin-dried to dry the solvent dimethyl ether on a rotary evaporator to obtain the wild chrysanthemum volatile oil ointment.

[0058] (2) Refining and dispersion of volatile oil of wild chrysanthemum: The volatile oil ointment of wild chrysanthemum obtained in step (1) is dispersed in camellia oil according to the volatile oil of wild chrysanthemum: camellia oil=1:9 (mass ratio) at 6°C After cooling, filter with qualitative filter paper to obtain oil containing wild chrysanthemum volatile oil.

[0059] (3) Preparation of microcapsules of wild chrysanthemum volatile oil: add a certain amount of β-cyclodextrin into distilled water, the concentration of the obtained β-cyclodextrin solution is 0.7% (w/w), and it is dissolved by heating at 70°C. After heat preservation and stirring to saturation, place it in a constant temperature oscillator, and then add the wild chrysanthemum volatile oil in step (2) according to the core-wall mass ratio of 1:7.5 (the core material is wild chrysanthemum volatile oil and grease, and the wall material is cyclodextrin) Grease, keep the temperature at 55℃ and shake for 3h, cool to room temperature and put it in the refrigerator (3~5℃). After the precipitation has separated out, filter with suction, wash the clathrate with absolute ethanol, and finally put the cleaned clathrate in an oven Dry at 45°C to obtain wild chrysanthemum volatile oil microcapsules.

[0060] (4) Preparation of diarrhea and antipruritic balm:

[0061] Phase A: 10 parts of white beeswax, 3 parts of ozokerite, 0.05 parts of butylated hydroxytoluene;

[0062] Phase B: 9 parts of borneol;

[0063] Phase C: 0.05 parts of propyl paraben, 69 parts of petrolatum, 1 part of tocopherol acetate;

[0064] Phase D: 1.3 parts of menthol;

[0065] Phase E: 6 parts of wild chrysanthemum volatile oil microcapsules, 0.3 parts of bisabolol.

[0066] Stir and heat phase A to 86°C until the solid wax is completely melted into liquid, then cool to 84°C and add phase B, stir until the solid is completely melted into liquid, continue to cool to 79°C, add phase C, and stir until the solid is completely melted Turn into liquid, cool to 72℃, add phase D, stir well until the solid is completely melted, continue to cool to 62℃, add phase E, stir well, discharge the material, fill it while hot to obtain microcapsules of wild chrysanthemum volatile oil Balm.

Example Embodiment

[0067] Example 2

[0068] Preparation of antidiarrheal and antipruritic balm for infants and young children:

[0069] (1) Preparation of wild chrysanthemum volatile oil ointment: the wild chrysanthemum is washed, dried, and crushed through a 60-mesh sieve to obtain wild chrysanthemum powder. Put the wild chrysanthemum powder in the extraction kettle, add subcritical fluid dimethyl ether (DME) according to the ratio of material to liquid of 1:7 (g:mL), extraction temperature is 28℃, extraction pressure is 0.8MPa, extraction is 5.5 h Obtain the subcritical initial extract of wild chrysanthemum, the solvent is recovered to the solvent tank by the circulating compressor, recycled, and extracted 3 times, and then the initial extracts obtained 3 times are combined. Finally, the initial extract was spin-dried to the solvent dimethyl ether by a rotary evaporator to obtain the volatile oil ointment of wild chrysanthemum.

[0070] (2) Refining and dispersion of volatile oil of wild chrysanthemum: The volatile oil ointment of wild chrysanthemum obtained in step (1) is dispersed in camellia oil at a mass ratio of 1:6, cooled at 9°C, and filtered with qualitative filter paper to obtain the The fat of chrysanthemum essential oil.

[0071] (3) Preparation of wild chrysanthemum volatile oil microcapsules: add a certain amount of β-cyclodextrin into distilled water to obtain a β-cyclodextrin solution with a concentration of 2.1%, heat it at 70°C to dissolve it, keep it warm and stir until saturated In the constant temperature oscillator, add the volatile oil of wild chrysanthemum in step (2) at a core-to-wall mass ratio of 1:6, keep the temperature at 40℃, shake for 4.5h, cool to room temperature and put it in the refrigerator, and filter after precipitation , Wash the clathrate with absolute ethanol, and finally put the cleaned clathrate in an oven to dry at 45°C to obtain wild chrysanthemum volatile oil microcapsules.

[0072] (4) Preparation of diarrhea and antipruritic balm:

[0073] Phase A: 11.5 parts of white beeswax, 2.5 parts of ozokerite, 0.04 parts of butylated hydroxytoluene;

[0074] Phase B: 7.5 parts of borneol;

[0075] Phase C: 0.04 parts of propyl paraben, 60 parts of petrolatum, 0.7 parts of tocopherol acetate;

[0076] Phase D: 0.7 parts of menthol;

[0077] Phase E: 5 parts of wild chrysanthemum volatile oil microcapsules, 0.5 parts of bisabolol.

[0078] Stir and heat phase A to 89°C until the solid wax is completely melted into liquid, then reduce the temperature to 86°C and add phase B. After stirring until the solid is completely melted into liquid, continue to cool to 75°C, add phase C, and stir until the solid is completely melted. Turn the temperature to 73°C, add phase D, stir well until the solid is completely melted, continue to cool to 68°C, add phase E, stir well, discharge the material, fill it while hot to obtain microcapsules of wild chrysanthemum volatile oil Balm.

Example Embodiment

[0079] Example 3

[0080] Preparation of antidiarrheal and antipruritic balm for infants and young children:

[0081] (1) Preparation of wild chrysanthemum volatile oil ointment: the wild chrysanthemum is washed, dried, and crushed through a 70-mesh sieve to obtain wild chrysanthemum powder. Put the wild chrysanthemum powder in the extraction kettle, add the subcritical fluid dimethyl ether (DME) according to the ratio of material to liquid of 1:9, the extraction temperature is 15℃, the extraction pressure is 0.6MPa, and the wild chrysanthemum subcritical is extracted for 5 hours. The initial extract and the solvent are recovered to the solvent tank by the circulating compressor, recycled, and extracted 3 times, and then the initial extracts obtained from the 3 times are combined. Finally, the initial extract was spin-dried to the solvent dimethyl ether by a rotary evaporator to obtain the volatile oil ointment of wild chrysanthemum.

[0082] (2) Refining and dispersion of volatile oil of wild chrysanthemum: The volatile oil of wild chrysanthemum obtained in step (1) is dispersed in camellia oil at a mass ratio of 1:8, cooled at 7°C, and filtered with qualitative filter paper to obtain the The fat of chrysanthemum essential oil.

[0083] (3) Preparation of wild chrysanthemum volatile oil microcapsules: add a certain amount of β-cyclodextrin into distilled water to obtain a β-cyclodextrin solution with a concentration of 1.5%, heat it at 70°C to dissolve it, keep it warm and stir until saturated In the constant-temperature oscillator, add the volatile oil of wild chrysanthemum in step (2) at a core-to-wall mass ratio of 1:4.5, keep the temperature at 45℃ and shake for 2.5h, cool to room temperature and put it in the refrigerator, and filter with suction after the precipitation has separated , Wash the clathrate with absolute ethanol, and finally put the cleaned clathrate in an oven to dry at 45°C to obtain wild chrysanthemum volatile oil microcapsules.

[0084] (4) Preparation of diarrhea and antipruritic balm:

[0085] Phase A: 9.5 parts of white beeswax, 4 parts of ozokerite, 0.06 parts of butylated hydroxytoluene;

[0086] Phase B: 8 parts of borneol;

[0087] Phase C: 0.06 parts of propyl paraben, 65 parts of petrolatum, 0.9 parts of tocopherol acetate;

[0088] Phase D: 1 part of menthol;

[0089] Phase E: 6.8 parts of wild chrysanthemum volatile oil microcapsules, 0.1 part of bisabolol.

[0090] Stir and heat phase A to 87°C until the solid wax is completely melted into liquid, then reduce the temperature to 85°C and add phase B, stir until the solid is completely melted into liquid, continue to cool to 77°C, add phase C, and stir until the solid is completely melted Turn the temperature to 74°C, add phase D, stir well until the solid is completely melted, continue to cool down to 65°C, add phase E, stir evenly, discharge the material, fill it while hot to obtain microcapsules of wild chrysanthemum volatile oil Balm.

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the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine

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Balsam capable of removing prickly heat and relieving itching for infants as well as preparation method and application of balsam

AI-Extracted Technical Summary

Problems solved by technology

Abstract

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Examples

Example Embodiment

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Description & Claims & Application Information

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