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Foaming sunscreen compositions comprising ultraviolet radiation absorbing compound and superhydrophilic amphiphilic copolymer

A technology of amphiphilic copolymers and compositions, which can be used in medical preparations containing active ingredients, skin care preparations, cosmetics, etc., and can solve problems such as increasing the challenges of mild and foamable sunscreens

Active Publication Date: 2021-09-07
JOHNSON & JOHNSON CONSUMER COPANIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The challenge of creating mild and foamable sunscreens is further compounded if there are additional constraints on the sunscreen composition

Method used

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  • Foaming sunscreen compositions comprising ultraviolet radiation absorbing compound and superhydrophilic amphiphilic copolymer
  • Foaming sunscreen compositions comprising ultraviolet radiation absorbing compound and superhydrophilic amphiphilic copolymer
  • Foaming sunscreen compositions comprising ultraviolet radiation absorbing compound and superhydrophilic amphiphilic copolymer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment I

[0237] Example I EpiOcular TM Score

[0238] The following examples illustrate the mildness of certain compositions of the present invention. Compositions of the invention (E1 to E4) comprise hydrolyzed potato starch sodium dodecenyl succinate free of monomeric surfactants (e.g. cocamidopropyl betaine) and also polyglyceryl-10 laurate . The comparative composition contained the monomeric surfactant cocamidopropyl betaine. These examples are shown in Table 1 and were prepared as follows:

[0239] Inventive Examples E1 to E4 were prepared by the following method: The aqueous phase was prepared by premixing KELTROLCG-F with propylene glycol in the main vessel, then adding EDTA-NA2, POLYALDO10-1-L, EUXYL PE9010 and water to the mixture medium while heating to a temperature of 65°C to 70°C and mixing with a propeller mixer. Then add NATRASURF TM PS-111 and mix until homogeneous. The oil phase was prepared by mixing NEOHELIOPAN HMS, NEOHELIOPAN OS / BP, NEOHELIOPAN 357, NEOHE...

Embodiment II

[0251] Example III Foam quality and formulation phase stability and homogeneity

[0252] The following examples illustrate the phase stability and homogeneity of certain compositions of the invention. The compositions of the invention (E9 to E11) comprise styrene / acrylate copolymers (i.e. SUNSPHERES TM PGL) suspension. The comparative compositions (C4 to C6) contained powdered styrene / acrylate copolymers (i.e. SUNSPHERES TM powder). These examples are shown in Table 3 and were prepared as described above.

[0253] Phase stability and homogeneity are determined by visual inspection for any type of emulsion instability or phase separation such as oil precipitation, creaming, flocculation, and the like. Stability samples were monitored for 2 weeks at room temperature.

[0254]

[0255] As shown in Table 3, with SUNSPHERES TM Powder formulations (C4 to C6) compared to those containing SUNSPHERES TM Formulations of PGL suspensions (E9 to E11) showed better foam quality. ...

Embodiment V

[0262] Embodiment V formula foaming quality and performance

[0263] The following examples illustrate the foamability of certain compositions of the present invention. The composition (E8) according to the invention contains 99% of the UV absorbing compound in the oil phase. In contrast, the comparative composition (C11) contained 79% of the UV absorbing compound in the oil phase. These examples are shown in Table 5 and were prepared as described above.

[0264] Table 5: Formulation foaming properties as a function of UV absorbing compounds in the oil phase

[0265]

[0266]

[0267] As shown in Table 5, formulations containing no emollient exhibited better lather quality than formulations containing an effective amount of emollient (eg, Finsolv TN) to prevent foaming.

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Abstract

The foaming sunscreen compositions of the present invention comprise a continuous aqueous phase and a discontinuous oil phase dispersed in said aqueous phase, said continuous aqueous phase comprising from about 0.75% to about 6% of a superhydrophilic amphiphilic copolymer, The oil phase contains UV absorbing compounds, and the foaming sunscreen composition is substantially free of monomeric surfactants and substantially free of oil soluble polymers.

Description

technical field [0001] The present invention relates to a topically acceptable foaming sunscreen composition in the form of an oil-in-water emulsion comprising a UV absorbing compound and a superhydrophilic amphiphilic copolymer which exhibits low irritation and high shine Foamy. Background technique [0002] Prolonged exposure to UV radiation, such as from the sun, can lead to the formation of photodermatosis and erythema and increase the risk of skin cancers such as melanoma, and accelerate skin aging, such as loss of elasticity and wrinkling of the skin. [0003] Numerous sunscreen compositions are commercially available with varying abilities to shield the body from ultraviolet light. Unfortunately, many commercially available foamable sunscreens can sting the eyes or irritate the skin. Consumers therefore desire sunscreen formulations that are mild and capable of forming a high volume "glitter foam" with relatively low energy input. [0004] The challenge of producin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/06A61K8/73A61K8/86A61Q17/04
CPCA61K8/731A61K8/046A61K8/732A61Q17/04A61K8/345A61K8/35A61K8/37A61K8/44A61K8/4966A61K8/678A61K8/8152A61K8/86A61K2800/592A61K8/06A61K8/30A61K8/73A61Q17/00A61K2800/5922A61K2800/654
Inventor S·戴利P·迈特拉B·塞蒂亚万
Owner JOHNSON & JOHNSON CONSUMER COPANIES
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