Sugar-free type folium ginkgo and fiveleaf gynostemma herb collaterals-dredging soft capsules and preparation method thereof
A sugar-free, soft capsule technology, applied in capsule delivery, pharmaceutical formulations, medical raw materials derived from ginkgo biloba, etc., can solve problems such as low bioavailability, gastrointestinal discomfort, poor drug stability, etc., to avoid increased blood sugar, no Adverse reactions, good stability
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Embodiment 1
[0027] Example 1: A sugar-free traditional Chinese medicine Yinlan Tongluo Soft Capsule for oral administration
[0028] The soft capsule is composed of an encapsulation liquid and a capsule shell, wherein the encapsulation liquid is composed of 100 g of Ginkgo biloba leaves, 150 g of Gynostemma pentaphyllum in parts by weight, soybean oil as a dispersant, beeswax as a suspending agent, and soybean lecithin as a surfactant. constitute. Wherein the weight ratio of above-mentioned Chinese medicine extract and soybean oil, beeswax and soybean lecithin is 1~2: 3~5: 0.05~0.2: 0.1~0.3; 0.35, water 0.8 ~ 1.2 made. The recipe is:
[0029] (1) Preparation of the extract: take the above two herbs, add 8-10 times of water to extract twice at 90-100°C, the first time for 2 hours, the second time for 1 hour, filter, combine the filtrates, and extract Concentrate the solution to a relative density of 1.1-1.2, add ethanol to make the alcohol concentration of the drug solution 40%-60%, lea...
Embodiment 2
[0035] Example 2: A sugar-free traditional Chinese medicine Yinlan Tongluo Soft Capsule for oral administration
[0036] The soft capsule is composed of an encapsulation liquid and a capsule shell, wherein the encapsulation liquid is composed of 102 g of Ginkgo biloba leaves, 153 g of Gynostemma pentaphylla 153 g, dispersant soybean oil, suspending agent beeswax and surfactant soybean lecithin constitute. Wherein the weight ratio of above-mentioned Chinese medicine extract and soybean oil, beeswax and soybean lecithin is 1~2: 3~5: 0.05~0.2: 0.1~0.3; 0.35, water 0.8 ~ 1.2 made. Preparation method is the same as embodiment 1.
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