Preparation method for sijunzisan fermented by composite strains

A technology of composite strains and Junzisan, which is applied in the field of preparation of Sijunzisan fermented by complex strains, can solve the problems of inability to fully digest cellulose, difficult dissolution of active ingredients and utilization by animals, etc., to improve drug efficacy and bioavailability , increase the production and accumulation, the effect of reasonable composition

Inactive Publication Date: 2018-06-12
郑州六兴生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the composition of traditional Chinese medicine in Sijunzi Powder is rich in cellulose, and the poultry cannot fully digest cellulose, which makes it difficult for many active ingredients to dissolve and be used by animals

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Embodiment 1: a kind of preparation method of Sijunzi powder fermented by composite strains, is characterized in that: comprise the steps:

[0019] Step 1) Take 60 parts of Codonopsis pilosula, 60 parts of Atractylodes macrocephala (stir-fried), 60 parts of Poria cocos, and 30 parts of licorice (burnt) in the prescription of Sijunzi powder; wash with water, dry, and then crush into powder, the size of the powder is 40-80 mesh ; Obtain Chinese medicine powder for subsequent use;

[0020] Step 2) Fermentation with composite strains of solid-state fermentation strains, the composite strains of solid-state fermentation strains are: Bacillus licheniformis, Lactobacillus casei, Lactobacillus acidophilus and Bifidobacterium, Codonopsis endophyte No. 1;

[0021] Step 3), inoculate Bacillus licheniformis into a culture medium consisting of 5 grams of beef extract, 10 grams of peptone, 5 grams of sodium chloride, 20 grams of agar and 1000 milliliters of water. Cultivate at 34°C ...

Embodiment 2

[0058] Embodiment 2: a kind of preparation method of Sijunzi powder fermented by composite strains, is characterized in that: comprise the steps:

[0059] Step 1), take 60 parts of Codonopsis pilosula, 60 parts of Atractylodes macrocephala, 60 parts of Poria cocos, and 30 parts of licorice in the prescription of Sijunzi powder; wash with water, dry, and then pulverize into powder, the powder size is 40-80 mesh; get Chinese medicine powder, and set aside ;

[0060] Step 2), using composite strains for solid-state fermentation fermentation, the composite strains used for solid-state fermentation are: Bacillus licheniformis, Lactobacillus casei, Lactobacillus acidophilus, Bifidobacterium and Codonopsis endophyte No. 1;

[0061] Step 3), inoculate Bacillus licheniformis into a medium consisting of 5 parts of beef extract, 10 parts of peptone, 5 parts of sodium chloride, 20 parts of agar and 1000 parts of water, and cultivate it at 34 degrees using a constant temperature shaker Th...

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PUM

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Abstract

The invention belongs to a fermentation technology of adding traditional Chinese medicines in a microbial reproduction process, and particularly relates to a preparation method for sijunzisan fermented by composite strains, and the preparation method comprises the following steps: getting 60 parts of radix codonopsis, 60 parts of rhizoma atractylodis macrocephalae (fried), 60 parts of poria cocosand 30 parts of liquorice root (roasted); solid-state fermentation strains of the composite strains are adopted to ferment, and the solid-state fermentation strains are respectively as follows: bacillus licheniformis, lactobacillus casei, lactobacillus acidophilus, bifidobacterium and NO.1 radix codonopsis endophyte. The sijunzisan fermented by composite strains is a traditional Chinese medicine microbial ecological agent which completely substitutes antibiotics, is free of drug residues, prevents diseases and promotes growth; and sijunzisan and compound bacteria have cooperative effect on animmune system, and therefore, a veterinary drug produced by sijunzisan fermented by composite strains has immune ability which is superior to the immune ability of other products and common sijunzisan.

Description

technical field [0001] The invention belongs to the fermentation technology of adding traditional Chinese medicine in the process of microorganism propagation, and in particular relates to a preparation method of Sijunzi powder fermented by compound strains. Background technique [0002] Siwei Junzi Powder is composed of four kinds of traditional Chinese medicines, namely Codonopsis pilosula, Atractylodes macrocephala (stir-fried), Poria cocos, and licorice (steamed). , licorice (burnt) 30 parts. Codonopsis pilosula is sweet in taste, neutral in nature, invigorating the middle and nourishing qi, and harmonizing the spleen and stomach. Its active ingredient saponins can improve the body’s immunity; Poria cocos, glycosides and polysaccharides; Poria cocos is sweet in taste and neutral in nature, clears dampness and promotes water; invigorates the spleen and stomach; calms the mind and calms the nerves, its active ingredient Poria cocos polysaccharide has an excellent effect o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/14A61P1/14A61P37/04A61P31/14A61P31/16
CPCA61K9/14A61K36/076A61K36/284A61K36/344A61K36/484A61K2236/19A61K2300/00
Inventor 张新厚郜来林张策张会娟
Owner 郑州六兴生物科技有限公司
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