Breeding method for selecting high-production-performance A2A2 homozygous genotype dairy cattle based on pedigree information simplification

Abstract

The invention discloses a breeding method for selecting high-production-performance A2A2 homozygous genotype dairy cattle based on pedigree information simplification. By performing dairy cattle production performance measurement, pedigree data and phenotype data of dairy cattle individuals are collected, on the basis of a father beta casein genotype result, genetic evaluation is performed, breeding values of the milk yield, the butterfat yield, the milk protein yield and the milk protein rate are obtained, and high-yield A2A2 homozygous individuals are obtained through analysis by calculatingan individual high production index HPI. According to the method, by applying daily DHI data for large group screening, the workloads of the actual cattle farm production process are greatly lowered;the A2A2 homozygous individuals in the cattle herd can be rapidly, conveniently and accurately screened out.

Description

technical field [0001] The invention belongs to the technical field of dairy cow breeding, and in particular relates to a breeding method for simplified selection of high-production-performance A2A2 homozygous genotype dairy cows based on pedigree information. Background technique [0002] The protein in milk is the main material basis for the quality of milk, mainly casein and whey protein. Casein accounts for about 80% of milk protein, including four types: alpha s1, alpha s2, beta, and kappa. Beta (β) casein accounts for about 30% of the total protein. Studies have reported that β-casein has 13 types, including A1, A2, A3, A4, B, C, D, E, F, H1, H2, I, and G. Type A1 and A2 β-casein are the two most common types in dairy cow populations. The difference lies in a base change in the β-casein gene, which results in the amino acid at the corresponding position changing from proline to histidine. It is precisely because of the above-mentioned change of an amino acid that th...

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Problems solved by technology

[0003] Molecular genetic breeding is an effective means of dairy cow breeding. By detecting different variant types of β-casein, A2-type bulls and cows can be screened out, and A2 homozygous cows can be cultivated, such as CN105925717A, CN107287292A, CN105219839A , CN105018582A, and CN105018581A disclose detection methods and corresponding kits for distinguishing different variant types of β-casein, which provide effective means for the breeding of A2 homozygous dairy cows. It is too large, or further operations such as breeding and breeding are required, and it is often impossible to take into account the high-yielding performance of dairy cows. Therefore, it is of great production and economic significance to invent a simplified and effective breeding method for high-yielding A2 dairy cows

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