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Medicine composition used for treating diabetes mellitus

A composition and technology for diabetes, applied in drug combinations, metabolic diseases, pharmaceutical formulations, etc., to achieve the effects of improving insulin resistance, protecting islet cell function, and lowering cholesterol

Inactive Publication Date: 2018-06-15
王桂芬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can be used alone or in combination with sulfonylureas or insulin for the treatment of obese diabetes, so it is widely used clinically. The common adverse reactions of metformin are gastrointestinal discomfort, such as nausea, vomiting, diarrhea, abdominal pain, constipation, Bloating, indigestion, heartburn, etc., therefore, limit the use of metformin

Method used

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  • Medicine composition used for treating diabetes mellitus
  • Medicine composition used for treating diabetes mellitus
  • Medicine composition used for treating diabetes mellitus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0039] Embodiment: The pharmaceutical composition is made up of following raw material:

[0040] Eupatorium extract 330g, sealwort 330g, ginseng 170g, bitter melon 990g, wild papaya 650g, chayote 330g and metformin 500g.

[0041] (1) Dry and pulverize ginseng, sealwort, wild papaya, bitter gourd and chayote at 45-50°C respectively to 120-mesh fine powder;

[0042] (2) Take Eupatorium, add 4 to 6 times the amount of water each time, decoct twice, the first time is 1.5 to 2 hours, and the second time is 0.5 to 1 hour, combine the two decoctions, filter, and concentrate the filtrate At 80-85°C, add ethanol to the clear ointment with a relative density of 1.08-1.10, so that the alcohol content of the clear ointment reaches 70%, let it stand for 24 hours, recover ethanol, and concentrate at 50-55°C to a relative density of 1.30-1.32 The clear ointment, dried, Zelan extract, and then crushed into 120 mesh fine powder;

[0043] (3) Mix metformin with the fine powder prepared in (1)...

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Abstract

The invention relates to a medicine composition used for treating diabetes mellitus. The medicine composition is prepared from, by weight, 30-35 parts of herba lycopi extract, 30-35 parts of rhizoma polygonati, 15-20 parts of radix ginseng, 95-105 parts of bitter gourds, 60-70 parts of stanuntonia chinensis, 30-35 parts of chayote and 45-55 parts of melbine. When the medicine composition is applied to a patient for improving type 2 diabetes mellitus insulin resistance and treating poor Western medicine control and improving and reversing abnormal glucose tolerance of an early-state patient inclinical observation, the effect is obviously superior to that of the patient who purely uses melbine, the composition is reasonable, the compatibility is moderate, used drugs are precise and specific, when many drugs are combined, the synergistic effect can be better given play to, the insulin resistance is improved, islet cells are protected, obesity can also be improved, and adverse reactions can be reduced.

Description

technical field [0001] The invention relates to a pharmaceutical composition using metformin and Chinese herbal medicine as raw materials, in particular to a pharmaceutical composition for treating diabetes. Background technique [0002] Diabetes is a common disease caused by the interaction of genetic and environmental factors. It belongs to the category of "diabetes" in traditional Chinese medicine. Its pathogenesis is blood stasis, dryness and heat, injury of yin, and loss of yin and body fluid. The pathological characteristics are based on spleen and kidney yin deficiency, blood stasis and dryness and heat as the standard, and they are mutually causal. Clinically, it is marked by three excesses and one deficiency and hyperglycemia. If diabetes is not treated effectively, it can cause damage to multiple systems of the body. Insufficient absolute or relative secretion of insulin and decreased sensitivity of target tissue cells to insulin, causing a series of metabolic di...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P3/10A61K31/155
CPCA61K31/155A61K36/185A61K36/258A61K36/42A61K36/48A61K36/53A61K36/8969A61K2300/00
Inventor 王桂芬赵志库
Owner 王桂芬
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