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Traditional Chinese medicine composition for acute period of gout

An acute stage, composition technology, applied in the field of formula Chinese medicine, to achieve the effects of inhibiting uric acid production, enhancing joint function, and improving liver metabolism

Inactive Publication Date: 2018-08-10
浙江史迪姆生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The sound description of metabolic biology roughly means that the long-term intake of too much purine in the diet exceeds the body’s ability to metabolize purine, or due to age, the body’s ability to metabolize and excrete purine decreases, resulting in long-term excessive purine content in the purine metabolic pool. High, because improving the metabolic capacity by nourishing the spleen, nourishing the kidney, promoting blood circulation, dredging the collaterals to improve excretion capacity, supplemented by dietary regimen, is another good way to treat gout

Method used

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  • Traditional Chinese medicine composition for acute period of gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The traditional Chinese medicine composition for the acute stage of gout, including 5 grams of red rattan, 5 grams of Qinpi, 10 grams of astragalus, 5 grams of Cortex Phellodendri, 10 grams of Schisandra chinensis, and 5 grams of licorice. The preparation method comprises the following steps:

[0029] 1) Grinding the raw material of traditional Chinese medicine, soaking in 90% ethanol for 48 hours, using the reflux extraction method, filtering the medicinal residue with 80-120 mesh, distilling and concentrating under reduced pressure, and drying the concentrate to obtain the alcohol extract;

[0030] 2) Step 1) is made into a dosage form to obtain drug A.

Embodiment 2

[0032] The traditional Chinese medicine composition for the acute stage of gout, including 23 grams of red vine, 30 grams of Qinpi, 10 grams of astragalus, 15 grams of Phellodendron phellodendri, 15 grams of Schisandra chinensis, 25 grams of licorice, 60 grams of Sangkan, 10 grams of Shenjincao, 10 grams of chicory root, Front grass 10, its preparation method, comprises the steps:

[0033] 1) Grind the raw materials of traditional Chinese medicine (except Sangkan), soak in 90% ethanol for 48 hours, use the reflux extraction method, filter the dregs with 80‐120 mesh, distill and concentrate under reduced pressure, and then dry and powder the concentrate to obtain alcohol Extract;

[0034] 2) dry and powder the Sangkan;

[0035] 3) Mix the product of step 1) and step 2) to make a dosage form to obtain drug B.

Embodiment 3

[0037] The traditional Chinese medicine composition for the acute stage of gout, including 15 grams of red rattan, 5 grams of Qinpi, 20 grams of astragalus, 15 grams of Cortex Phellodendri, 20 grams of Schisandra chinensis, 15 grams of licorice, 20 grams of Shenjincao, and 15 grams of chicory root. The preparation method includes Follow the steps below:

[0038] 1) Grinding the raw material of traditional Chinese medicine, soaking in 90% ethanol for 48 hours, using the reflux extraction method, filtering the medicinal residue with 80-120 mesh, distilling and concentrating under reduced pressure, and drying the concentrate to obtain the alcohol extract;

[0039] 2) Step 1) is made into a dosage form to obtain drug C.

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Abstract

The invention discloses a traditional Chinese medicine composition for an acute period of gout. The traditional Chinese medicine composition is prepared from 5 to 30g of caulis sargentodoxae, 5 to 30gof cortex fraxini, 1 to 30g of radix astragali seu hedysari, 1 to 30g of cortex phellodendri, 1 to 30g of fructus schisandrae chinensis and 1 to 30g of liquorice root or any one or two or three or four of mulberry fruits, herba lycopodii, chicory root and herba plantaginis. According to the traditional Chinese medicine composition disclosed by the invention, a series of pharmacodynamic research results on single traditional Chinese medicines in a traditional Chinese medicine modernization process show that in a Western medicine theory, the traditional Chinese medicine composition is obtainedby preferring certain traditional Chinese medicines capable of remarkably inhibiting the generation of uric acid, improving the liver metabolism, improving the metabolic capacity of livers and promoting the discharge capacity of kidneys; a patent medicine can realize the effects of clearing away heat and removing dampness, promoting blood circulation and removing obstruction in channels, improvingpartial blood circulation and metabolism and enhancing a joint movement function according to a compatibility rule of monarch, minister, assistant and guide in a traditional Chinese medicine theory;the traditional Chinese medicine composition can directly reach a focus, the healing time is short and diseases do not easily recur after being healed.

Description

technical field [0001] The invention belongs to the technical field of formula traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for acute gout. Background technique [0002] Gout is hyperuricemia caused by purine metabolism disorder and / or decreased excretion of uric acid. Hyperuric acid is deposited in the joints in the form of monosodium urate (MSU) crystals. A normal adult produces about 750 mg of uric acid per day, 80% of which is endogenous and 20% is exogenous uric acid, of which about 200 mg is catabolized by the intestinal tract, and about 400 mg is excreted by the kidneys, so as to maintain the stability of the uric acid level in the body. Excessive involvement of exogenous sources or weakened excretory energy can lead to hyperuricemia. Gout is more common in middle-aged men, and women account for only 5%, mainly postmenopausal women, and the incidence of gout tends to be younger. Decreased metabolic capacity is...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K36/756A61P19/06
CPCA61K36/11A61K36/185A61K36/28A61K36/48A61K36/481A61K36/484A61K36/486A61K36/57A61K36/605A61K36/63A61K36/68A61K36/756A61K36/79A61K2236/333A61P19/06A61K2300/00
Inventor 屈彩云
Owner 浙江史迪姆生物科技有限公司