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Purification method of fermented cordyceps sinensis powder

A purification method and technology of Cordyceps sinensis, which is applied in the field of preparation of fermented Cordyceps fungus powder, can solve the problems of environmental pollution, low solid yield of fermented Cordyceps fungus powder, etc., and achieve the effects of reducing purification cost, controlling purification cost, and convenient operation

Inactive Publication Date: 2018-09-04
HUBEI CHUANGLI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the above-mentioned deficiencies in the prior art, the present invention provides a method for purifying Cordyceps sinensis fermented bacterial powder. On the basis of plate and frame filtration, the method further performs ultrafiltration membrane filtration on the filtrate of plate and frame filtration, and the prepared finished product The yield of fermented Cordyceps powder solids is higher than 90%, which solves the shortcomings of low solids yield of fermented Cordyceps powder produced by the prior art and is easy to cause environmental pollution, and ensures the yield of fermented Cordyceps powder solids at the same time , effectively control the purification cost

Method used

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  • Purification method of fermented cordyceps sinensis powder

Examples

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Effect test

Embodiment 1

[0028] Purify with 100kg of fermented Cordyceps bacterium liquid as raw material, select the ceramic membrane with a filter aperture of 150nm as the ultrafiltration membrane, and the purification process includes the following steps:

[0029] 1. Pickling

[0030] (1) First, clean the plate and frame filter and ultrafiltration membrane with tap water until the cleaning solution is clear.

[0031] (2) wash with the dilute sulfuric acid solution of 0.5wt% with concentration, the dilute sulfuric acid solution flow rate setting value is 360L / (h·m 2 ). Detect the flow rate of the dilute sulfuric acid solution through the microfiltration membrane. When the flow rate is higher than the set value of the acid liquid flow rate, stop pickling; and collect the pickling liquid into the acid liquid collection tank for the next pickling of the filter material.

[0032] 2. Alkaline washing

[0033] (1) Wash the plate-and-frame filter and ultrafiltration membrane acid-washed in step 1 with t...

Embodiment 2

[0043] Purify with 100kg of fermented Cordyceps bacterium liquid as raw material, select the ceramic membrane with a filter aperture of 200nm as the ultrafiltration membrane, and the purification process includes the following steps:

[0044] 1. Pickling

[0045] (1) First, clean the plate and frame filter and ultrafiltration membrane with tap water until the cleaning solution is clear.

[0046] (2) wash with the dilute sulfuric acid solution of 1.0wt% with concentration, the dilute sulfuric acid solution flow rate setting value is 360L / (h·m 2 ). Detect the flow rate of the dilute sulfuric acid solution through the microfiltration membrane. When the flow rate is higher than the set value of the acid liquid flow rate, stop pickling; and collect the pickling liquid into the acid liquid collection tank for the next pickling of the filter material.

[0047] 2. Alkaline washing

[0048] (1) Wash the plate-and-frame filter and ultrafiltration membrane acid-washed in step 1 with t...

Embodiment 3

[0058] Purify with 100kg of fermented Cordyceps bacterium liquid as raw material, select the ceramic membrane with a filter pore size of 300nm as the ultrafiltration membrane, and the purification process includes the following steps:

[0059] 1. Pickling

[0060] (1) First, clean the plate and frame filter and ultrafiltration membrane with tap water until the cleaning solution is clear.

[0061] (2) wash with the dilute sulfuric acid solution of 1.5wt% with concentration, the dilute sulfuric acid solution flow rate setting value is 360L / (h·m 2 ). Detect the flow rate of the dilute sulfuric acid solution through the microfiltration membrane. When the flow rate is higher than the set value of the acid liquid flow rate, stop pickling; and collect the pickling liquid into the acid liquid collection tank for the next pickling of the filter material.

[0062] 2. Alkaline washing

[0063] (1) Wash the plate-and-frame filter and ultrafiltration membrane acid-washed in step 1 with ...

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Abstract

The invention relates to a preparation technology of fermented cordyceps sinensis powder, in particular to a purification method of fermented cordyceps sinensis powder. The method comprises the stepsof acid cleaning, alkali cleaning, sheet frame filtration, ultrafiltration membrane filtration, and drying and grinding. According to the purification method of the fermented cordyceps sinensis powder, filtrate of the sheet frame filtration is further subjected to the ultrafiltration membrane filtration on a basis of the sheet frame filtration; a solid yield of the fermented cordyceps sinensis powder in a prepared finished product is higher than 90%; and the method solves the technical problem of the low solid yield of the fermented cordyceps sinensis powder produced in the prior art. An acidcleaning solution used by the method can be used for acid cleaning of filtration equipment repeatedly; an alkaline cleaning solution is repeatedly used for alkali cleaning of the filtration equipment;and environmental pollution of chemical substances is significantly reduced. The method guarantees the solid yield of the fermented cordyceps sinensis powder, and is simple in technology and convenient to operate at the same time, and the purification cost is effectively controlled.

Description

technical field [0001] The invention relates to a preparation process of fermented cordyceps fungus powder, in particular to a method for purifying cordyceps sinensis fermented fungus powder. Background technique [0002] Cordyceps sinensis has unique medicinal value and extensive pharmacological effects. Cordyceps sinensis enters the lungs and kidneys. It is sweet, warm and not dry. The role of reproductive function. Modern pharmacology has proved that Cordyceps sinensis can enhance the body's cellular immunity, treat liver fibrosis, chronic hepatitis B, nephritis, IgA nephropathy, chronic glomerulonephritis, diabetic nephropathy, chronic renal failure, as well as anti-cytomegalovirus infection, anti-tumor , lower blood fat, prevent arteriosclerosis and other effects. [0003] Cordyceps sinensis is a unique product of the plateau at an altitude of 3,000 to 5,000 meters. The market supply is limited and a large number of substitutes are needed, and artificially fermented C...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068A61K9/14
CPCA61K9/14A61K36/068A61K2236/51A61K2236/53
Inventor 张仁刘刘少敏谢华郭传功
Owner HUBEI CHUANGLI PHARMA