Preparation method and application of immunological enhancement compound tablets for pets

A pet and synergistic technology, applied in the field of pet medicine, can solve the problem of unable to identify mutant cells and so on

Inactive Publication Date: 2018-09-21
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, for animal organisms with low immunity, their immunocompetent cells cannot

Method used

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  • Preparation method and application of immunological enhancement compound tablets for pets
  • Preparation method and application of immunological enhancement compound tablets for pets
  • Preparation method and application of immunological enhancement compound tablets for pets

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Embodiment Construction

[0015] The composite immune booster for pets of the present invention is described in detail below in conjunction with specific examples, and the preparation steps are as follows:

[0016] 1. Extraction of bursa active peptide BP-IV

[0017] Take 4kg of healthy 4-6 week-old chicken bursa, extract BP-IV, crush and mix with 6L normal saline, freeze and thaw three times, then centrifuge, take the supernatant, ultrafilter, 1000Da ultrafiltration membrane, freeze Dry filtrate; sample was diluted with PBS, and then centrifuged at 12000 for 10min, then passed through a 0.22um filter membrane; molecular sieve (Sephadex G-50) purification analysis, harvesting activity peak, and freeze-drying; B solution (2% acetonitrile, 0.065% trifluoroacetic acid ) was diluted, centrifuged at 12000g for 10min, and then filtered with a 0.22um filter membrane; the filtrate was reversed for HPLC purification analysis, and the active peak with a retention time of 20.25min was harvested; by solid-phase ch...

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Abstract

The invention provides a compound polysaccharide immunological enhancement agent for pets and a preparation method and application thereof. The enhancement agent is prepared from bursa fabricius bioactive peptide BP-IV, mannan oligosaccharide, vitamin A, adhesive, disintegrant and lubricant. The enhancement agent has a good immunological enhancement effect on the pets, the capacity for the organisms to resist pathogen infection can be enhanced, and the health level of the organisms is improved. Compared with existing anti-infection medicine, the enhancement agent is a good pet compound for enhancing immunity, can be used for clinically preventing infectious diseases, and has high application value in improving the immunological capacity of the organisms of the pets.

Description

technical field [0001] The invention belongs to the field of pet medicines, and relates to a composite tablet for pets with an immune-enhancing effect, as well as its technology and application. Background technique [0002] With the improvement of people's living standards, the rapid development of urbanization and the reduction of urban family size, pets have gradually become a part of people's lives. Statistics show that the number of pets in Chinese cities has exceeded 100 million, and the growth rate is getting faster and faster. The rising pet fever has attracted more and more people's attention. At present, pet infectious diseases are still an important factor restricting the healthy feeding of pets. With the development of modern veterinary medicine and immunology, it has been found that the occurrence and development of many pet infectious diseases are closely related to the dysfunction or defect of the body's immune system. Therefore, in pets The prevention and c...

Claims

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Application Information

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IPC IPC(8): A61K38/02A61K9/20A61K47/36A61K47/12A61P37/04A61K31/07A61K31/702
CPCA61K38/02A61K9/2013A61K9/2059A61K31/07A61K31/702A61P37/04A61K2300/00
Inventor 单虎秦志华张慧杨瑞梅张传美
Owner QINGDAO AGRI UNIV
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