Application of heparin sodium to preparation of external drug for treating haemorrhoids

Abstract

The invention provides the application of heparin sodium to the preparation of an external drug for treating haemorrhoids. The heparin sodium is acid mucopolysaccharide-heparin (The molecular weight is 4000-15000), can interfere with many links in the hemagglutination process and has an anti-coagulation effect both in vivo and in vitro; in combination with antithrombin III (AT-III), the heparin sodium mainly enhances an inhibitory effect of the latter on activated coagulation factors II, IX, X, XI and XII and has the effects of preventing platelet aggregation and damage, hindering the formation of thromboplastin, preventing prothrombin from becoming thrombin and inhibiting thrombin, thereby preventing fibrinogen from becoming fibrinogen and playing an anti-coagulation role. The invention utilizes heparin for dermatology (heparin sodium cream) to treat internal and external hemorrhoids, mixed hemorrhoids and acute thrombotic hemorrhoid and applies the anticoagulation, blood stasis and thrombolysis effects of the heparin sodium to relieve swelling and pain; a blood vessel is dredged, retracted and restored, so that the haemorrhoids is treated. The heparin sodium is applied to an anus(Pay attention to discontinuation when bleeding occurs) and is safe, convenient and effective.

Description

technical field [0001] The invention relates to an externally used medicine for treating hemorrhoids, in particular to a medicine for treating hemorrhoids containing heparin sodium as the main active ingredient and a display medicine thereof. Background technique [0002] Hemorrhoids are masses formed by congestion, enlargement and buckling of the submucosal and subcutaneous hemorrhoidal venous plexuses of the lower rectum and anal canal. There are still differences in the causes and opinions of hemorrhoid formation. There are vascular proliferation theory, varicose vein theory, anal canal stenosis theory and anal cushion downshifting theory, because hemorrhoid venous return obstruction and local inflammation and injury are the main causes. External hemorrhoids can cause thrombosis of the subhemorrhoidal venous plexus due to strenuous exercise, overwork, or straining to defecate. The above content can be found in the third edition of "General Surgery Handbook", author: Fang...

AI Technical Summary

Problems solved by technology

If the blood stasis is relieved at this time, the hemorrhoidal veins will return to normal state and function, and the "hemorrhoids" will disappear! The usual surgical treatment is to cut off the hemorrhoidal vein and remove the stagnant part, which destroys the integrity of the hemorrhoidal vein, causing great damage, long course of disease, more pain, and high cost; externally used medicines, whether domestic or foreign, have antibacterial functions. , analgesia, anesthesia, astringent, anti-inflammatory, etc., there is no specialized drug for the treatment