Traditional Chinese medicine composition for preventing and curing trichomonad of dove, as well as preparation method and application thereof

A technology of trichomoniasis and composition, applied in the field of traditional Chinese medicine composition and its preparation for preventing and treating trichomoniasis in pigeons, capable of solving animal pancreatitis and central nervous system damage, causing public safety problems, and reducing production performance of meat pigeons to achieve significant public health significance and environmental protection significance, obvious preventive and therapeutic effects, and the effect of solving the problem of drug residues

Inactive Publication Date: 2018-10-12
广东科贸职业学院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Metronidazole has always been the first-selected drug for the prevention and treatment of pigeon trichomoniasis, but metronidazole has certain toxicity, not only has life-long carcinogenic and mutagenic effects, but also can cause side effects of animal pancreatitis and central nervous system damage. Cause the reduction of the production performance of meat pigeons and the generation of drug resistance. In recent years, drug resistance has obviously appeared in production, which will cause public safety problems. In addition, because the unique parents of meat pigeons directly feed the pigeons, the pigeons are about 20 days old. The market has become a food raw material, the production cycle is extremely short, and the potential harm caused by metronidazole drug residues to the human body is more prominent. Finding new alternative drugs has become an inevitable choice

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A traditional Chinese medicine composition for preventing and treating trichomoniasis of pigeons, which is composed of the following traditional Chinese medicines in parts by weight: 5 parts of Sophora flavescens, 5 parts of Changshan, 4 parts of Smilax smilax, 3 parts of Pulsatilla chinensis, 3 parts of Artemisia annua, and 2 parts of licorice.

[0024] The preparation method of the Chinese medicine composition of above-mentioned prevention and treatment pigeon trichomoniasis, this method comprises the following steps:

[0025] (1) Sophora flavescens, Radix Changshan, and Pulsatilla pulsatillae were soaked in citric acid solution (PH2 citric acid) at 80°C for 10 hours, and the infusion was collected and concentrated until the mass concentration was twice that of the crude drug (m / v);

[0026] (2) Artemisia annua is hot-soaked with 45wt% ethanol at 80°C for 24 hours, and the infusion is collected and concentrated until the mass concentration is twice that of the crude dr...

Embodiment 2

[0032] A traditional Chinese medicine composition for preventing and treating trichomoniasis of pigeons, which is composed of the following traditional Chinese medicines in parts by weight: 6 parts of Sophora flavescens, 6 parts of Changshan, 4 parts of Smilax smilax, 2 parts of Pulsatilla chinensis, 2 parts of Artemisia annua, and 2 parts of licorice.

[0033] The preparation method of the Chinese medicine composition of above-mentioned prevention and treatment pigeon trichomoniasis, this method comprises the following steps:

[0034] (1) Sophora flavescens, Radix Changshan, and Pulsatilla pulsatillae were soaked in citric acid solution (PH2 citric acid) at 80°C for 10 hours, and the infusion was collected and concentrated until the mass concentration was twice that of the crude drug (m / v);

[0035] (2) Artemisia annua is hot-soaked with 45wt% ethanol at 80°C for 24 hours, and the infusion is collected and concentrated until the mass concentration is twice that of the crude dr...

Embodiment 3

[0042] Referring to Example 2, the difference is that the traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 5 parts of Sophora flavescens, 5 parts of Changshan, 6 parts of Smilax, 4 parts of Pulsatilla, 4 parts of Artemisia annua, and 1 part of Licorice.

[0043] The preparation method of the Chinese medicine composition of above-mentioned prevention and treatment pigeon trichomoniasis, this method comprises the following steps:

[0044] (1) Sophora flavescens, Radix Changshan, and Pulsatilla pulsatillae were soaked in citric acid solution (PH2 citric acid at 75°C for 11 hours, and the infusion was collected and concentrated until the mass concentration was twice that of the crude drug (m / v);

[0045] (2) Artemisia annua is hot-soaked with 40wt% ethanol at 85°C for 24 hours, and the infusion is collected and concentrated until the mass concentration is twice that of the crude drug (m / v);

[0046] (3) Smilax ...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and curing trichomonad of dove. The traditional Chinese medicine composition for preventing and curing the trichomonadof dove is prepared from the following traditional Chinese medicines in parts by weight: 4 to 8 parts of radix sophorae flavescentis, 4 to 8 parts of radix dichroae, 4 to 8 parts of rhizoma smilacisglabrae, 2 to 6 parts of roots of Chinese pulsatilla, 2 to 6 parts of sweet wormwood herb, and 1 to 3 parts of licorice root. The traditional Chinese medicine composition for preventing and curing thetrichomonad of dove provided by the invention, as a pure Chinese herbal medicine preparation, has the characteristics of pure nature and no residues, has remarkable and preventing and curing effectson the trichomonad of dove, can replace metronidazole, solves the problems of drug residues and bacterial resistance caused by the metronidazole, and has remarkable public health significance and environmental protection significance.

Description

Technical field: [0001] The invention relates to the field of traditional Chinese medicine compound preparations, in particular to a traditional Chinese medicine composition for preventing and treating trichomoniasis in pigeons, a preparation method and application thereof. Background technique: [0002] Pigeon trichomoniasis caused by Trichomonas fowl is one of the common diseases in the meat pigeon breeding industry. The main symptoms of sick pigeons are emaciation and diarrhea. Autopsy shows that there are obvious button-shaped yellow deposits or ulcers on the mucous membrane of the throat. . The disease can infect meat pigeons of all ages. Squab pigeons and young pigeons under 3 months of age are particularly susceptible, and the mortality rate can reach more than 50%. It often causes serious economic losses to the breeding of meat pigeons. The loss amounted to more than 200 million yuan. [0003] Metronidazole has always been the first-selected drug for the prevention...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/90A61K9/08A61K47/12A61K47/10A61P33/02
CPCA61K9/0095A61K36/185A61K36/282A61K36/484A61K36/489A61K36/71A61K36/896A61K36/90A61K47/10A61K47/12A61P33/02A61K2300/00
Inventor 刘思伽刘国乾姜文联黄爱芳邱深本方心灵张君阮国安康艳梅
Owner 广东科贸职业学院
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