Injectable biocompatible bone matrix used for facial bone repair and preparation method thereof

Abstract

The invention discloses an injectable biocompatible bone matrix used for facial bone repair and a preparation method thereof. The injectable biocompatible bone matrix is formed by mixing 5 to 10 partsof homogeneous or heterogeneous soft bone through acellular disposal, 5 to 10 parts of bone tissues homogeneous with the soft bone through degreasing, decalcification and decellularization, 10 partsof collagen fibril and 75 parts of distilled water in physiological conditions. The injectable biocompatible bone matrix has the beneficial effects that the binding performance of the material with human bones is preferable by simulating the composition of human body soft bones, the initial strength is relatively high, rapid repair for human body soft bone tissue damage is facilitated, and the injectable biocompatible bone matrix can be applicable to nose beautifying.

Description

technical field [0001] The invention belongs to the technical field of bioengineering, in particular to an injectable biocompatible bone matrix for facial bone repair. Background technique [0002] Cartilage is the basic raw material for human bone development. When human cartilage tissue is damaged, the cartilage regeneration ability is poor due to the limited cartilage repair ability of the human body. Leading to damage to cartilage is known as one of the problems of orthopedic surgery. [0003] At present, the commonly used treatment methods for cartilage injury are transplantation of autologous cartilage or transplantation of allogeneic cartilage, but new cartilage defects are likely to occur when autologous cartilage is transplanted, and there is an immunogenic reaction in allogeneic cartilage transplantation, so the regeneration and repair of cartilage damage has become an important issue in orthopedics. Clinical research hotspot. [0004] Modern surgical operations ...

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Problems solved by technology

[0003] At present, the commonly used treatment methods for cartilage injury are transplantation of autologous cartilage or transplantation of allogeneic cartilage, but new cartilage defects are likely to occur when autologous cartilage is transplanted, and there is an immunogenic reaction in allogeneic cartilage transplantation, so the regeneration and repair of cartilage damage has become an important issue in orthopedics. Clinical Research Hotspots

[0004] Modern surgical operations are developing in a minimally invasive way, and so is orthopedic surgery. However, traditional cartilage repair surgery often requires a large surgical incision, and the postoperative recovery marks are obvious, which brings great troubles to the postoperative life of patients.