Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Flexible sweat sensor as well as preparation method and application thereof

A sensor and sweat technology, applied in the field of sensors, can solve the problems of low medical application value and poor matching of indicators required for disease monitoring.

Inactive Publication Date: 2018-11-16
HUBEI UNIV OF CHINESE MEDICINE
View PDF11 Cites 19 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the current research on wearable devices is relatively hot, most of their functions are still focused on sports testing, fitness assistance, etc. Most wearable devices have low medical application value and cannot match the indicators required for disease monitoring.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Flexible sweat sensor as well as preparation method and application thereof
  • Flexible sweat sensor as well as preparation method and application thereof
  • Flexible sweat sensor as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0044] The present invention provides the preparation method of the flexible sweat sensor described in the above scheme, comprising the following steps:

[0045] preparing a first gold electrode, a second gold electrode and a reference electrode on the surface of the flexible substrate;

[0046] Depositing a first Prussian blue layer and a second Prussian blue layer on the surface of the first gold electrode and the second gold electrode by electrochemical cyclic voltammetry;

[0047] After the chitosan-carbon nanotube-glucose oxidase mixed gel solution is drip-coated on the surface of the first Prussian blue layer, it is dried to form a glucose working electrode;

[0048] The chitosan-carbon nanotube-lactate oxidase mixed gel solution was drop-coated on the surface of the second Prussian blue layer and then dried to form a lactic acid working electrode and obtain a flexible sweat sensor.

[0049] The invention prepares the first gold electrode, the second gold electrode and ...

Embodiment 1

[0068](1) Preparation of the first gold electrode and the second gold electrode: first, the PEI substrate is cleaned with acetone, isopropanol, and oxygen plasma respectively, and then a layer of 30nmCr / 50nmAu is photoetched using photoresist and electron beam evaporation technology layer, and then wash off the Cr layer with acetone solution, and then deposit a layer of 500nm thick parylene insulating layer, and finally expose the gold electrode with oxygen plasma.

[0069] (2) Deposit a layer of Prussian blue on the surface of the first gold electrode and the second gold electrode by electrochemical cyclic voltammetry, deposition voltage: -0.5 ~ 0.5V, scan rate: 20mV / s, number of scan cycles: 1 cycle; deposition solution is FeCl 3 , KCl and K 3 Fe(CN) 6 A mixed solution in which FeCl 3 The concentration of KCl is 2.5mM, the concentration of KCl is 100mM, K 3 Fe(CN) 6 The concentration is 2.5mM;

[0070] (3) Drop-coat 20 microliters of chitosan (0.5wt%), carbon nanotubes...

Embodiment 2

[0074] (1) Preparation of the first gold electrode and the second gold electrode: first, the PEI substrate is cleaned with acetone, isopropanol, and oxygen plasma respectively, and then a layer of 30nmCr / 50nmAu is photoetched using photoresist and electron beam evaporation technology layer, and then wash off the Cr layer with acetone solution, and then deposit a layer of 500nm thick parylene insulating layer, and finally expose the gold electrode with oxygen plasma.

[0075] (2) Deposit a layer of Prussian blue on the surface of the first gold electrode and the second gold electrode by electrochemical cyclic voltammetry, deposition voltage: -0.4 ~ 0.4V, scan rate: 20mV / s, number of scan cycles: 3 cycles, deposition solution is FeCl 3 , KCl and K 3 Fe(CN) 6 A mixed solution in which FeCl 3 The concentration of KCl is 2.5mM, the concentration of KCl is 100mM, K 3 Fe(CN) 6 The concentration is 2.5mM;

[0076] (3) Drop-coat 20 microliters of a mixture containing chitosan (5w...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Diameteraaaaaaaaaa
Thicknessaaaaaaaaaa
Diameteraaaaaaaaaa
Login to View More

Abstract

The invention provides a flexible sweat sensor. The flexible sweat sensor comprises a flexible substrate as well as a glucose working electrode, a lactic acid working electrode and a reference electrode which are arranged on the surface of the flexible substrate. Glucose oxidase (or lactate oxidase) on the electrode is utilized for oxidizing glucose (or lactic acid) in sweat to generate hydrogen peroxide; hydrogen peroxide can directly perform reduction reaction on the electrode; reduction current is detected through an electrochemical workstation and then the concentrations of the glucose andlactic acid in the sweat can be obtained according to the current magnitude and a standard curve. According to the preparation method disclosed by the invention, the response current level is improved by utilizing a Prussian blue layer to speed up the decomposition of hydrogen peroxide; the sensor disclosed by the invention has high sensitivity; the minimum detection limit for the glucose reaches10nM and the minimum detection limit for lactic acid reaches 1mu M.

Description

technical field [0001] The invention relates to the technical field of sensors, in particular to a flexible sweat sensor and its preparation method and application. Background technique [0002] Flexible electronic technology is an emerging electronic technology that manufactures electronic devices on flexible substrates. Because of its unique flexibility, ductility, high efficiency, and low cost, it has broad application prospects in information, energy, medical, national defense and other fields. [0003] The rapid development of smart materials and flexible electronics has opened up a new path for smart wearable applications such as monitoring and early warning of the internal and external environment of the human body, portable medical care, and human-computer interaction. Although the current research on wearable devices is relatively hot, most of their functions are still focused on sports testing and fitness assistance. Most wearable devices have low medical applicati...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/327G01N27/26G01N27/48
CPCG01N27/26G01N27/308G01N27/3271G01N27/3272G01N27/3277G01N27/48
Inventor 张国军李玉桃丁帆唐丽娜
Owner HUBEI UNIV OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com