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Pharmaceutical composition for preventing and treating saprolegniasis of aquatic animals and preparation method of pharmaceutical composition

An aquatic animal and composition technology, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients to achieve the effects of unique technology, prevention of saprolegniasis in aquatic animals, and no drug resistance.

Active Publication Date: 2018-11-20
BEIJING CENT BIOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing studies have shown that Galla gall has a certain control effect on Saprolegniasis, so there are also other traditional Chinese medicines that are effective against Saprolegniasis

Method used

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  • Pharmaceutical composition for preventing and treating saprolegniasis of aquatic animals and preparation method of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Prescription ratio: 40 parts of Chuanxiong, 20 parts of Cnidium, 10 parts of Gentiana, 10 parts of Sappan, 10 parts of ebony, 10 parts of Magnolia officinalis, 10 parts of Schisandra, and 10 parts of Galla.

[0025] The prepared 65% ethanol solution was poured into the extraction tank according to 10 times the volume of the medicinal material, and after sealing, the temperature was raised to 80° C., and the reflux extraction was carried out for 3 times, 1 hour each time. The refluxed extract was rapidly cooled to room temperature, centrifuged at 8000rpm online at high speed, and concentrated under low pressure at 50°C to the same volume as the original medicinal material. Use 1 times the amount of rice bran as an auxiliary material to absorb the concentrated solution, mix it fully in a mixing tank, dry it in a drying oven at 70°C, and pulverize it to obtain the product.

Embodiment 2

[0027] Prescription ratio: 60 parts of Chuanxiong, 40 parts of Cnidium, 20 parts of Gentiana, 20 parts of Sappan, 20 parts of ebony, 20 parts of Magnolia officinalis, 20 parts of Schisandra, and 20 parts of Galla.

[0028] The prepared 65% ethanol solution was poured into the extraction tank according to 10 times the volume of the medicinal material, and after sealing, the temperature was raised to 80° C., and the reflux extraction was carried out for 3 times, 1 hour each time. The refluxed extract was rapidly cooled to room temperature, centrifuged at 8000rpm online at high speed, and concentrated under low pressure at 50°C to the same volume as the original medicinal material. Use 1 times the amount of rice bran as an auxiliary material to absorb the concentrated solution, mix it fully in a mixing tank, dry it in a drying oven at 70°C, and pulverize it to obtain the product.

Embodiment 3

[0030] Prescription ratio: Cnidium 40 parts, Gentiana 20 parts, Sappan 20 parts, Magnolia officinalis 20 parts, Schisandra 20 parts, Galla chinensis 20 parts.

[0031] The prepared 65% ethanol solution was poured into the extraction tank according to 10 times the volume of the medicinal material, and after sealing, the temperature was raised to 80° C., and the reflux extraction was carried out for 3 times, 1 hour each time. The refluxed extract was rapidly cooled to room temperature, centrifuged at 8000rpm online at high speed, and concentrated under low pressure at 50°C to the same volume as the original medicinal material. Use 1 times the amount of rice bran as an auxiliary material to absorb the concentrated solution, mix it fully in a mixing tank, dry it in a drying oven at 70°C, and pulverize it to obtain the product.

[0032] 1. Research on the inhibition and killing of saprolegniasis by the product on aquatic animals

[0033] 1.1 Purpose of the test

[0034] Verify th...

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Abstract

The invention provides pharmaceutical composition prepared from pure traditional Chinese medicines and used for preventing and treating saprolegniasis of aquatic animals and a preparation method of the pharmaceutical composition. The composition is characterized by being prepared from radix chuanxiong, fructus cnidii, radix gentianae macrophyllae, sappan wood, dark plums, cortex magnoliae officinalis, fructus schisandrae chinensis and Chinese gall through reflux extraction by an ethanol solution, centrifugation, concentration, adsorption, drying and crushing. The composition has the benefits as follows: the pharmaceutical composition for preventing and treating the saprolegniasis of the aquatic animals is used for preventing and treating the saprolegniasis of the aquatic animals and can reduce loss caused by saprolegniasis disease in the aquatic animal breeding process.

Description

technical field [0001] The invention relates to the fields of traditional Chinese medicine, pharmacy and prevention and control of aquatic diseases, in particular to a pharmaceutical composition made of pure traditional Chinese medicine for preventing and treating saprolegniasis of aquatic animals and a preparation method thereof. Background technique [0002] Saprolegniasis is a disease caused by Saprolegniasis, a fungus on the surface of fish. It has become one of the main diseases in aquaculture and has caused heavy losses to fishery production. It is a kind of fish disease distributed worldwide. When the fish body surface is injured or local skin necrosis, saprolegniasis will take the opportunity to invade, and a large number of cotton-like hyphae will grow on the lesion, resulting in abnormal swimming of fish and shrimp and loss of appetite. , and even die of emaciation, causing heavy losses to fishery production. Saprolegniasis can occur all year round, among which wi...

Claims

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Application Information

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IPC IPC(8): A61K36/79A61K36/736A61P17/00A61P31/10A61K35/64
CPCA61K36/234A61K36/236A61K36/48A61K36/515A61K36/57A61K36/575A61K36/736A61K36/79A61K2236/333A61K2236/39A61K35/63A61P17/00A61P31/10A61K2300/00
Inventor 程安达吕慧源赵志超王志明侯晓礁陈立红秦俊杰李福元崔虎郭智伟王秀敏江厚生王顺山韩俊国梁伟王保山
Owner BEIJING CENT BIOLOGY
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