Composite cleaning liquid for chemiluminescent instrument pipeline and preparation method thereof

Abstract

The invention discloses composite cleaning liquid for a chemiluminescent instrument pipeline and a preparation method thereof. The composite cleaning liquid comprises the following components in partsby weight: 36 to 67 parts of sodium hydrogen phosphate, 33 to 55 parts of monopotassium phosphate, 12 to 21 parts of zinc chloride, 15 to 27 parts of sodium lauryl sulfate, 5 to 11 parts of glycerol,0.2 to 0.8 parts of potassium hydrogen phthalate, 0.1 to 0.4 parts of sodium hydroxide, 0.5 to 1 part of gentamicin, 39 to 61 parts of 2-morpholineethanesulfonic acid, 28 to 50 parts of dipotassium hydrogen phosphate, 11 to 29 parts of citric acid, 17 to 25 parts of polyethylene glycol, 4 to 8 parts of bovine serum albumin, 12 to 21 parts of sucrose, 0.5 to 1 part of Tween-20, 0.2 to 1 part of Proclin 300, and 300 to 500 parts of deionized water. The method utilizes the synergistic effect among the components to obtain the composite cleaning liquid for the chemiluminescent instrument pipeline, The preparation method of a diluent is simple, and is suitable for large-scale production in a factory. The cleaning liquid has good effect, little damage to the pipeline, and is suitable for long-term storage.

Description

technical field [0001] The invention relates to the field of immune technology, in particular to a composite cleaning solution for pipelines of chemiluminescent instruments and a preparation method thereof. Background technique [0002] Since the 1950s, the use of radiolabeled insulin was used to detect insulin, and the detection technology has developed rapidly. In 1977, with the help of the principle of radioimmunoassay, the chemiluminescence of enzymes and immune reactions were combined to develop chemiluminescence immunoassays. This method mainly uses luminescent substances or enzymes to label antigens or antibodies. After an immune reaction occurs, add The oxidant or enzyme substrate emits light, and the concentration of the analyte is reflected by the luminous intensity, and the immune reaction is mainly determined by the specificity of the antigen-antibody. The reaction process has gradually developed from manual operation to full-automatic mechanization. In addition...

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Problems solved by technology

The reaction process has gradually developed from manual operation to full-automatic mechanization. In addition to the influence of the reagent itself on the results, various pipelines in the instrument also have potential risks due to long-term operation, which may be caused by not cleaning after adding samples. Cleaning may affect the results, crystallization may occur due to long-term soaking of chemical reagents, which may affect the cleaning effect, and the cleaning effect may be reduced due to long-term storage of reagents, etc.

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