A traditional Chinese medicine composition for treating rigid parkinson's disease and its application

Abstract

The invention discloses a traditional Chinese medicine composition and an application thereof for treating parkinson's disease of stiff and immobile type. 30 parts by mass, 10-20 parts by mass of peach kernel, 10-20 parts by mass of Angelica sinensis, 20-30 parts by mass of Spatholobus papaya, 15-25 parts by mass of papaya, 15-30 parts by mass of Clematis, 10-20 parts by mass of Guangdilong 15-30 parts by mass of Radix Paeoniae Alba, 10-15 parts by mass of Magnolia officinalis, and 6-10 parts by mass of Radix Glycyrrhizae are obtained by decocting as raw materials. The traditional Chinese medicine composition can be made into a traditional Chinese medicine preparation for treating catalepsy and hypokinetic Parkinson's disease alone or with pharmaceutically acceptable carriers or auxiliary materials. The test results show that the traditional Chinese medicine composition of the present invention can effectively treat catalepsy and hypokinetic Parkinson's disease, has positive long-term curative effect, and is suitable for long-term administration.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating catalepsy and hypokinetic Parkinson's disease and its application, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by tremor, muscle rigidity, slowness of movement and abnormal posture, with a high disability rate. Clinical data show that Parkinson's disease is increasing at a rate of 100,000 new cases per year in my country, and has become the "third killer" that seriously threatens the physical and mental health of middle-aged and elderly people in my country after cardiovascular and cerebrovascular diseases and Alzheimer's disease. Family and society bring a heavy burden. According to its clinical manifestations, PD can be divided into tremor type, stiff and low-movement type, and mixed type. Among them, the stiff and low-movement type mainly ...

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicine clinical treatment of PD mainly uses levodopa preparations, anticholinergic drugs, DA receptor agonists, neuron protective agents, etc. Although taking the above western medicines can relieve the symptoms of stiffness and inactivity and achieve certain curative effects, but The above-mentioned western medicines all have side effects in varying degrees. For example, many toxic and side effects such as dyskinesia often appear in levodopa within 2-5 years of medication. Clinical compliance, limiting its clinical application

Since so far, Western medicine is still unable to prevent the progression of the disease, and its adverse reactions and other issues are still unresolved. Therefore, it is particularly important to find traditional Chinese medicine that can effectively treat catalepsy and hypokinetic Parkinson's disease.