A kind of poultry adenovirus, a kind of quadruple vaccine and preparation method thereof

A technology of avian adenovirus and avian influenza virus, applied in biochemical equipment and methods, viruses, vaccines, etc., can solve problems such as economic loss, harm, and severe immunosuppression, and achieve small immune dose, rapid antibody production, and immunogenicity Good results
CN109097340BActive Publication Date: 2021-07-30BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES
Publication Date
2021-07-30

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Abstract

The invention provides a new poultry adenovirus, a quadruple vaccine and a preparation method thereof. The new poultry adenovirus is a poultry adenovirus group I serotype 4 DC strain, which was preserved in China on April 25, 2018 The General Microbiology Center of the Microbiological Culture Collection Management Committee, the preservation number is CGMCC No.15589; the quadruple vaccine is a quadruple vaccine of Newcastle disease, avian influenza, infectious bursa and group I type 4 avian adenovirus DC strain. The quadruple vaccine of the present invention has good immunogenicity, rapid antibody generation after immunization, high antibody titer and long maintenance time, small immunization dose, easy injection of the selected adjuvant, and can prevent and treat four diseases with one injection. The advantages of high efficiency and good safety.
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Description

technical field

[0001] The invention belongs to the technical field of veterinary biological products, and in particular relates to a quadruple vaccine of avian adenovirus, a new type of Newcastle disease, avian influenza (H9 subtype), infectious bursa and avian adenovirus and a preparation method thereof. Background technique

[0002] Newcastle disease is caused by Newcastle disease virus, a highly contagious and acute septicemia infectious disease of poultry characterized by respiratory and gastrointestinal mucous membrane bleeding. Simultaneous infection with other pathogens such as H9 subtype avian influenza can cause endogenous infection, which will reduce the egg production of laying hens and increase the mortality of breeding chickens. It is one of the main diseases that endanger my country's poultry industry.

[0003] H9 subtype avian influenza is a low-pathogenic disease, but mixed infection with other pathogens, especially Newcastle disease and E. hazards. [000...

Claims

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