Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for chemically extracting purified water-soluble natural organic substances by solid film

A technology of organic substances and solid membranes, applied in the direction of solvent extraction of liquid solutions, etc., can solve the problems of reducing transmembrane pressure difference, extremely high pressure stability control requirements, and polluting industrial wastewater from extracts, so as to achieve separation efficiency and effect The effect of improving and reducing industrial wastewater discharge and solving potential safety hazards

Active Publication Date: 2019-05-10
GANSU UNIV OF CHINESE MEDICINE
View PDF5 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the inventor's follow-up research, it is found that the extraction method still has the following problems: since alkaloids, flavonoids, anthraquinones, organic acids, etc. are water-soluble organic substances, the overall polarity is relatively large, so that the separated substances are separated in the water phase. The partition coefficient with the organic extraction phase is suitable. This extraction method requires the use of more polar organic solvents, such as ethyl acetate, chloroform, n-butanol, ether, etc. These organic solvents have a certain solubility in water, and the solid film During the extraction process, the organic phase will continuously dissolve into the water phase at the membrane interface where the two phases are in contact, resulting in the continuous reduction of the recycled organic solvent, which not only wastes the organic solvent, pollutes the extract, but also produces industrial wastewater containing the extractant
At the same time, the boiling points of these organic solvents are all low, and they are volatile during use and become a safety hazard.
In addition, because solvents such as ethyl acetate and n-butanol will hydrophilically modify the surface of the solid membrane used for extraction and reduce the transmembrane pressure difference, it is easy to cause the interpenetration of the organic phase and the aqueous phase during the extraction process. Therefore, during the solid membrane extraction process, the pressure difference stability control on both sides of the membrane is extremely demanding, which affects the normal operation of the membrane extraction process.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for chemically extracting purified water-soluble natural organic substances by solid film

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Get 50kg of kudzu root, add 12 times of water to reflux extraction, extract 1.5 hours each time, extract 2 times, and combine to obtain 1100kg of extract; the extract is ultrafiltered with a ceramic membrane with a pore size of 10nm, and about 1000kg of ultrafiltration permeate is collected; % Trialkylphosphine oxide-sulfonated kerosene is the extraction agent, 0.05% NaOH solution is the stripping agent, and the ultrafiltration permeate is extracted and stripped according to the specific implementation steps of the present invention. The membrane extraction temperature is 20 ° C, and the stripping temperature is 35 ℃; the flow velocity of the ultrafiltration permeate, extractant, and back-extraction solution are 1.0m / min, 0.25m / min, and 0.65m / min, respectively, and the membrane extraction time is 12 hours; collect about 1000kg of back-extraction solution; The pH value of the liquid was adjusted to 4 with HCl, passed through a polyamide resin column, and eluted with 70% e...

Embodiment 2

[0047] Take 50 kg of rhubarb, add 20 times the amount of water to reflux extraction, extract 30 minutes each time, extract 2 times, and combine to obtain 900 kg of extract; the water extract is ultrafiltered with a ceramic composite membrane with a pore size of 20 nm to obtain an ultrafiltrate; Use 20% hydrochloric acid solution to adjust the pH to 3.0, use 5% trialkylphosphine oxide-sulfonated kerosene as the extraction agent, and 0.5% ammonia water as the stripping agent, and extract the ultrafiltration permeate according to the specific implementation steps of the present invention Back extraction, membrane extraction temperature is 25°C, back extraction temperature is 30°C; flow velocity of ultrafiltrate, extraction agent, and back extraction liquid are 2.0m / min, 0.3m / min, 1.0m / min respectively, and membrane extraction time is 8 hours ; Collect about 800kg of back extract; Concentrate the back extract under reduced pressure to 50kg, adjust the pH value to 2 with hydrochlori...

Embodiment 3

[0049] Take 50kg of licorice, add 24 times the amount of 0.75% ammonia water to reflux extraction, extract 1 hour each time, extract 3 times, and combine to obtain 1100kg of extract; ultrafilter the extract with a ceramic membrane with a pore size of 10nm, and collect about 1050kg of ultrafiltration permeate , adjust the pH value to 6 with hydrochloric acid, use 20% trialkylphosphine oxide-sulfonated kerosene as the extraction agent, and 0.07% NaOH solution as the stripping agent, and carry out the extraction and stripping of the ultrafiltration permeate according to the specific implementation steps of the present invention , the membrane extraction temperature is 25°C, the back extraction temperature is 40°C, the flow speeds of the ultrafiltrate, extraction agent, and back extraction liquid are 1.0m / min, 0.3m / min, and 0.65m / min respectively, and the total membrane extraction and back extraction liquid After 12 hours, about 1000 kg of back extract was obtained; the back extrac...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for chemically extracting purified water-soluble natural organic substances by a solid film. Based on an ultra-filtration-solid film extraction coupling technique, chemical extraction is combined with the ultra-filtration-solid film extraction coupling technique, so that chemical reaction among chemical extraction agents and functional groups of separated substances is implemented to form an extraction complex which can dissolve in an organic phase and is transferred to the organic phase, high separating selectivity is achieved, existence forms of the separatedsubstances in a water phase and the organic phase are different, the concentrations of the separated substances in an oil phase and the water phase and distribution coefficients of the separated substances in the oil phase and the water phase are unrelated, and the extraction rate of the separated substances is only related to the solubility degree of the extraction complex in the organic phase,so that the method can efficiently extract target material plant extracts with low concentration. The method is used for membrane extraction processes, ultra-filtration liquid, back-extracts and extracts are consistently cycled, more efficient and accurate extraction is achieved, and industrial operation is easily implemented.

Description

technical field [0001] The present invention relates to a method for purifying and separating water-soluble plant extracts, in particular to a method for solid film chemical extraction, purification and separation of water-soluble natural organic substances, which is mainly used in water such as alkaloids, flavonoids, anthraquinones and organic acids in plants. The invention discloses a method for separating and purifying natural organic substances with high solubility, belonging to the technical field of natural substance separation. Background technique [0002] Organic substances such as alkaloids, flavonoids, anthraquinones, and organic acids in plants often have multiple utilization values. After these substances are extracted from plants, in most cases, they need to be further separated and purified to improve their purity for easy utilization. At present, chromatography, precipitation, membrane separation, and liquid-liquid extraction are mainly used in industry for s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): B01D11/04
Inventor 魏舒畅
Owner GANSU UNIV OF CHINESE MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com