Traditional Chinese medicine composition for treating avascular necrosis of femoral head and application

A technology of ischemic necrosis and composition, applied in the direction of drug combination, medical preparations containing active ingredients, bone diseases, etc., to achieve the effects of improving microcirculation, dilating capillaries, promoting angiogenesis and ossification

Inactive Publication Date: 2019-05-17
郭明建
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the current traditional Chinese medicine formula for the treatment of femoral head necrosis, it is basically based on nourishing the kidney and strengthening the bones and promoting blood circulation to remove blood stasis, such as the "Huo Gu Wan" formula. However, with the in-depth research on femoral head necrosis in the field of traditional Chinese medicine, new For example, Chen Weiheng put forward the point of view of "treating from the spleen" in the early and middle stages of non-traumatic necrosis of the femoral head, and put forward the basic treatment principle of "treating phlegm and blood stasis at the same time" by invigorating the spleen and resolving phlegm, promoting blood circulation and dredging collaterals, and established a group consisting of Linggui Zhugan Decoction and Siwu Decoction are combined to invigorate the spleen and strengthen the bones. Codonopsis pilosula and Atractylodes macrocephala invigorate the spleen and replenish qi as the monarch drug; Guizhi and Chishao promote blood circulation and remove blood stasis, dredge collaterals and relieve pain, Poria cocos and pinellia help strengthen the spleen Take phlegm-resolving as ministerial medicine; angelica and rehmannia glutinosa promote blood circulation and nourish blood, add chuanxiong into the blood to regulate qi, then angelica and rehmannia glutinosa are used as adjuvant medicines; using licorice to reconcile the various medicines has achieved good curative effect, but How to combine old and new theories to treat early and late avascular necrosis of the femoral head, and how to effectively separate the primary and secondary for the cube has not been studied so far. A new formula has been developed to improve the treatment of early, middle and late avascular necrosis of the femoral head The curative effect can avoid the trouble caused by surgical treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Weigh the raw materials in the following parts by weight, and then decoct them to prepare a decoction.

[0051] 20 parts of Achyranthes knuckles, 18 parts of papaya, 15 parts of Dipsacus, 30 parts of Sagevine, 30 parts of Salvia miltiorrhiza, 15 parts of angelica, 15 parts of drynaria, 10 parts of Chuanqiong, 30 parts of motherwort, 15 parts of Fangji, 15 parts of Gentiana, 6 parts of ephedra, 10 parts of Gansong, 5 parts of cinnamon, 10 parts of safflower, 30 parts of parasite, 25 parts of golden dog spine, 15 parts of American ginseng, 15 parts of red ginseng, 10 parts of amomum, 12 parts of duhuo, 15 parts of red peony , 3 parts of clove, 9 parts of Paoshanjia, 15 parts of Xuanhu, 12 parts of tangerine peel, 15 parts of hawthorn, 30 parts of rehmannia and 30 parts of Morinda officinalis.

Embodiment 2

[0053] Weigh the following raw materials in parts by weight, add auxiliary materials, and combine with modern technology to prepare powder.

[0054] 28 parts of Achyranthes knuckles, 18 parts of papaya, 16 parts of Dipsacus, 28 parts of Sagevine, 28 parts of Danshen, 18 parts of Angelica, 12 parts of Rhizoma Drynariae, 10 parts of Chuanqiong, 30 parts of Motherwort, 15 parts of Fangji, 15 parts of Gentiana, 6 parts of ephedra, 7 parts of Gansong, 3 parts of cinnamon, 10 parts of safflower, 30 parts of parasitic, 22 parts of golden dog ridge, 10 parts of American ginseng, 10 parts of red ginseng, 5 parts of amomum, 12 parts of duhuo, 12 parts of red peony, 2 parts of clove, 7 parts of Paoshanjia, 15 parts of Xuanhu, 10 parts of tangerine peel, 12 parts of hawthorn, 32 parts of Rehmannia glutinosa and 30 parts of Morinda officinalis.

Embodiment 3

[0056] The raw materials of the following parts by weight are weighed and processed into pills.

[0057] 30 parts of Achyranthes knuckles, 18 parts of papaya, 13 parts of Dipsacus, 28 parts of Sagevine, 30 parts of Salvia miltiorrhiza, 12 parts of angelica, 15 parts of drynaria, 12 parts of Chuanqiong, 32 parts of motherwort, 14 parts of Fangji, 15 parts of Gentiana, 6 parts of ephedra, 8 parts of Gansong, 6 parts of cinnamon, 9 parts of safflower, 29 parts of parasite, 25 parts of golden dog spine, 14 parts of American ginseng, 8 parts of red ginseng, 6 parts of amomum, 10 parts of duhuo, 13 parts of red peony , 3 parts of clove, 10 parts of Paoshanjia, 12 parts of Xuanhu, 12 parts of tangerine peel, 13 parts of hawthorn, 29 parts of Rehmannia glutinosa and 30 parts of Morinda officinalis.

[0058] Clinical application of the present invention:

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Abstract

The invention provides a traditional Chinese medicine composition for treating avascular necrosis of the femoral head and application. The traditional Chinese medicine composition is prepared from radix achyranthis bidentatae, pawpaws, radix dipsaci, roots of schisandra henryi clarke, radix salviae miltiorrhizae, angelica sinensis, rhizoma drynariae, ligusticum wallichii, herba leonuri, rhizoma sinomeni cauliset, radix gentianae macrophyllae, ephedra, rhizoma nardostachyos, cortex cinnamomi, safflowers, mistletoe, cibotium barometz, American ginseng, radix ginseng rubra, fructus amomi, radix angelicae pubescentis, radix paeoniae rubras, cloves, parched pangolin scales, rhizoma corydalis, tangerine peels, hawthorns, prepared rehmannia roots and radix morindae officinalis. The traditional Chinese medicine composition for treating avascular necrosis of the femoral head has the advantages that effects of tonifying the kidney, strengthening bone, activating blood and removing stasis serve as the main aim, effects of adjusting the spleen and stomach and reducing phlegm serve as the auxiliary aim, and compounding is conducted; blood capillaries are effectively expanded, capillary resistance is reduced, microcirculation is improved, the local anoxia condition is improved, the necrosis process is stopped or prevented, blood-vessel regeneration and ossification are promoted, the clinicalcuring effect can be achieved if early treatment is conducted, and if treatment is conducted in the middle and later period, an operation can be avoided.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating avascular necrosis of the femoral head and its application. Background technique [0002] Avascular necrosis of femoral head (ANFH) is a common clinical disease characterized by necrosis of bone trabeculae and bone marrow in indefinite areas caused by different etiologies destroying the blood supply of the femoral head. In recent years, the incidence has been increasing day by day. Most patients are under 50 years old. It is one of the refractory orthopedic diseases. It has attracted great attention from all over the world. The global incidence of this disease is gradually increasing. , there is an urgent need to take measures to prevent its occurrence and to obtain early diagnosis as much as possible. [0003] Traditional Chinese medicine believes that femoral head necrosis belongs to the category of bone numbne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P19/08A61K35/36
Inventor 郭明建
Owner 郭明建
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