A kind of camellia antibacterial hand sanitizer and preparation method thereof

A technology of camellia and hand sanitizer, which is applied in the field of cleaning agents, can solve the problems of unmade camellia hand sanitizer and polyphenol content requirements, and achieve the effect of industrialized large-scale production, easy picking, and definite curative effect

Active Publication Date: 2022-02-15
SHAANXI NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent application with the notification number CN103145770A discloses a method for extracting polyphenols from camellias, but this method does not require the content of polyphenols, nor does it make camellia hand sanitizer

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  • A kind of camellia antibacterial hand sanitizer and preparation method thereof
  • A kind of camellia antibacterial hand sanitizer and preparation method thereof
  • A kind of camellia antibacterial hand sanitizer and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0047] Camellia ethanol extract 5.0%, ether alcohol monosulfosuccinate disodium salt (MES) 10.0%, cocamidopropyl betaine (CAB-35) 30.0%, glycerin and propylene glycol mixture (volume ratio 1:2) 3.0%, hyaluronic acid 2.0%, potassium 2,4-hexadienoate 1.0%, sodium carboxymethylcellulose (CMC-Na) 2.0%, disodium ethylenediaminetetraacetic acid (EDTA-2Na) 0.8%, and the balance is distilled water.

[0048] The preparation method of the camellia antibacterial hand sanitizer of the present embodiment is as follows:

[0049] (1) preparation of camellia ethanol extract

[0050] S1 prepares camellia powder:

[0051] Select fresh and complete camellias in the initial flowering stage and full flowering stage, rinse them with tap water and distilled water for 5 times, dry them in the shade, crush them with a pulverizer, pass through a 150-mesh sieve, and dry them at 50-55°C to constant weight to obtain camellia powder.

[0052] S2 Separation and purification of camellia ethanol extract: ...

Embodiment 2

[0065] Camellia antibacterial hand sanitizer is made of the following components by weight percentage: Camellia ethanol extract 7.5%, MES10.0%, CAB-35 30.0%, glycerin and propylene glycol mixture (volume ratio 1:2) 2.0%, hyaluronic acid 2.0%, potassium 2,4-hexadienoate 1.5%, CMC-Na 1.0%, EDTA-2Na 0.8%, and the balance is distilled water.

[0066] The preparation method of the camellia antibacterial hand sanitizer of the present embodiment is the same as that of embodiment 1.

Embodiment 3

[0068] Camellia antibacterial hand sanitizer is made of the following components by weight percentage: Camellia ethanol extract 5.0%, MES 5.0%, CAB-35 25.0%, glycerin and propylene glycol mixture (volume ratio 1:2) 2.0%, hyaluronic acid 3.0%, potassium 2,4-hexadienoate 1.5%, CMC-Na 2.0%, EDTA-2Na 0.8%, and the balance is distilled water.

[0069] The preparation method of the camellia antibacterial hand sanitizer of the present embodiment is the same as that of embodiment 1.

[0070] In order to determine the optimal formulation of the camellia antibacterial hand sanitizer involved in the present invention, optimize the preparation method of the camellia antibacterial hand sanitizer, evaluate the antibacterial effect and performance quality of the camellia antibacterial hand sanitizer, a large number of experimental studies have been carried out, various tests details as following:

[0071] 1. Antibacterial effect experiment of camellia ethanol extract

[0072] 1.1 Experimen...

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Abstract

The invention discloses a camellia antibacterial hand sanitizer and a preparation method thereof, which is prepared from the following components in weight percentage: 5.0%-10.0% of camellia ethanol extract, 5.0%-10.0% of ether alcohol sulfosuccinic acid monoester disodium salt 10.0%, Cocamidopropyl Betaine 20.0%~30.0%, Glycerin and Propylene Glycol Mixture (Volume Ratio 1:2) 2.0%~3.0%, Hyaluronic Acid 1.0%~3.0%, Potassium 2,4-Hexadienoate 0.5% ~1.5%, sodium carboxymethylcellulose 1.0%~3.0%, disodium edetate 0.8%, the balance is distilled water. The hand sanitizer disclosed by the invention has high safety, good antibacterial effect, controllable quality, mildness and no stimulation, and can effectively inhibit Staphylococcus aureus, Escherichia coli, Bacillus cereus, etc. Standard, some performance indicators are better than similar products on the market.

Description

technical field [0001] The invention belongs to the technical field of cleaning agents, and in particular relates to a camellia antibacterial hand sanitizer and a preparation method thereof. Background technique [0002] Hand sanitizer is one of the important daily necessities in daily life, with a wide variety and large consumption. As the main cleaning product in personal homes and public places, hand sanitizer is closely related to health. A high-quality antibacterial hand sanitizer should have the characteristics of high safety, strong detergency, good antibacterial activity, and low irritation. However, the hand sanitizers currently on the market are either focused on cleaning and decontamination, and are powerless to common pathogenic bacteria on the hands, or the antibacterial ingredients contained in the hand sanitizer are chlorine and phenol chemicals, which will not only irritate the hands for a long time skin, and may also pollute the environment. Therefore, it...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61Q19/10A61Q17/00A61P31/04A61P31/10
CPCA61K8/9789A61Q19/10A61Q17/005A61P31/04A61P31/10A61K2800/84Y02A50/30
Inventor 张华峰周雪雪杨晓华
Owner SHAANXI NORMAL UNIV
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