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Preparation method of cosmetic antioxidant based on sparassis crispa extracts

An anti-oxidant, hydrangea technology, applied in the field of cosmetic additives, can solve the problems of unsatisfactory anti-oxidation effect, relatively high process requirements, easy loss of activity, etc., to improve anti-oxidation effect, improve solubility, and improve biocompatibility sexual effect

Inactive Publication Date: 2019-08-23
FUQING CITY FIRE KIRIN EDIBLE FUNGUS TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditional common antioxidants: vitamin E, vitamin C, β-carotene, but the antioxidant effect is not ideal, the production process requirements are relatively high, and it is easy to lose activity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A preparation method for cosmetic antioxidants based on hydrangea extract, comprising the following steps:

[0025] (1) Mix the dried hydrangea fruiting bodies with water at a volume ratio of 1:30, adjust the pH to 8.5 with sodium bicarbonate, and then shake and extract in a water bath at 65°C for 3 hours. The obtained crude extract was deproteinized and precipitated with 3 times the volume of 95% ethanol to obtain a precipitate, which was washed alternately with ethanol and ether for 3 times and then dried to obtain Hydrangea extract. Among them, the method of deproteinizing the crude extract: the crude extract was prepared into a 5% saturated solution, mixed with Sevage reagent, shaken vigorously, and then centrifuged at 2700r / min for 9min to remove denatured proteins.

[0026] (2) Hydrangea extract, hydrogenated lecithin, and idebenone were mixed at a mass ratio of 10:1.5:0.8, and ultrasonically treated at an ultrasonic power of 535W for 75 minutes to obtain a capsul...

Embodiment 2

[0029] A preparation method for cosmetic antioxidants based on hydrangea extract, comprising the following steps:

[0030] (1) Mix the dried hydrangea fruiting bodies with water at a volume ratio of 1:25, adjust the pH to 8 with sodium bicarbonate, and then shake and extract in a water bath at 60°C for 2 hours. The obtained crude extract was deproteinized and precipitated with 3 times the volume of 95% ethanol to obtain a precipitate. The precipitate was alternately washed twice with ethanol and ether and then dried to obtain the hydrangea extract. Among them, the method of deproteinizing the crude extract: the crude extract was prepared into a 5% saturated solution, mixed with Sevage reagent, shaken vigorously, and then centrifuged at 2500r / min for 8min to remove denatured proteins.

[0031] (2) After mixing hydrangea extract, hydrogenated lecithin, and idebenone at a mass ratio of 10:1:0.5, ultrasonic treatment was performed at an ultrasonic power of 530W for 60 minutes to o...

Embodiment 3

[0034] A preparation method for cosmetic antioxidants based on hydrangea extract, comprising the following steps:

[0035] (1) Mix the dried hydrangea fruiting bodies with water at a volume ratio of 1:35, adjust the pH to 9 with sodium bicarbonate, and then shake and extract in a water bath at 70°C for 4 hours. The obtained crude extract was deproteinized and precipitated with 3 times the volume of 95% ethanol to obtain a precipitate, which was washed alternately with ethanol and ether for 4 times and then dried to obtain Hydrangea extract. Among them, the method of deproteinizing the crude extract: the crude extract was prepared into a 5% saturated solution, mixed with Sevage reagent, shaken vigorously, and then centrifuged at 3000r / min for 10min to remove denatured proteins.

[0036] (2) Hydrangea extract, hydrogenated lecithin, and idebenone were mixed in a mass ratio of 10:2:1, and ultrasonically treated at an ultrasonic power of 540W for 90 minutes to obtain the capsule c...

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Abstract

The invention relates to the technical field of cosmetic additives, in particular to a preparation method of cosmetic antioxidant based on sparassis crispa extracts. The method comprises the followingsteps that 1, the sparassis crispa extracts are extracted from sparassis crispa sporocarp; 2, the sparassis crispa extracts, hydrogenated lecithin and idebenone are mixed and then subjected to ultrasonic treatment, and a capsule core is obtained; 3, urea and 37-40% formalin are mixed and stirred on the conditions that the pH value is 8-10, and the temperature is 60-80 DEG C, and a first solutionis obtained; n-octadecane is heated and fused and then mixed with the capsule core and an emulsifier, stirring and emulsification are conducted for 30-45 minutes on the conditions that the pH value is4-5, and the temperature is 60-70 DEG C, and a second solution is obtained; the first solution is added in the second solution, standing is conducted for 2-3 hours, then the pH value is adjusted to be 6-7, and the cosmetic antioxidant is obtained. According to the method, operation is easy, the prepared antioxidant is not prone to inactivation, and the antioxidant effect is good.

Description

technical field [0001] The invention relates to the technical field of cosmetic additives, in particular to a method for preparing an antioxidant for cosmetics based on Hydrangea extract. Background technique [0002] People obtain oxygen through breathing to carry out various oxidative metabolic reactions necessary for the human body. In this process, some unstable substances are inevitably produced. These substances are very active and will react with other substances. These unstable substances are free radicals. Antioxidants are substances that effectively inhibit the oxidation reaction of free radicals. Their mechanism of action is to directly act on free radicals or indirectly consume substances that are prone to generate free radicals to prevent further reactions. [0003] The biggest threat to skin aging comes from oxidation. Radiation, ultraviolet rays, environmental pollution, insufficient work and rest time, etc. will cause the skin to generate a large number of fr...

Claims

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Application Information

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IPC IPC(8): A61K8/9728A61K8/35A61K8/55A61K8/42A61Q19/08
CPCA61K8/355A61K8/42A61K8/553A61K2800/82A61Q19/08A61K8/9728
Inventor 陈美英王国强何绍东
Owner FUQING CITY FIRE KIRIN EDIBLE FUNGUS TECH DEV
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