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Antiviral compound traditional Chinese medicine preparation for pigs and preparation method of preparation

A compound traditional Chinese medicine and anti-virus technology, which is applied in the direction of anti-viral agents, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of poor immune effect of vaccines, lack of cross-protection, and easy recurrence, etc. Infection and incidence ratio of swine viral diseases, improving production performance and vaccine immunity, reducing diarrhea rate

Active Publication Date: 2019-09-20
LONGYAN UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, it is mainly prevented and controlled by vaccine immunization. When the disease occurs, hyperimmune serum can be injected, and the mortality rate can be controlled by emergency immunization. The cured or resistant pigs may be infected for life, the growth immune function will decline, and the economic value will be lost.
[0003] In addition, hyperimmune serum is expensive, and the utilization rate of pig farms is not high. The control of these diseases mainly relies on vaccine immunization. However, some diseases such as porcine reproductive and respiratory syndrome and porcine circus disease will cause immunosuppression and make pigs infected Other diseases or immune failure, etc.; or some viral diseases have different serotypes, genotypes, etc., and different serotypes and genotypes of the injected vaccine may not have cross-protection; viruses may mutate during the evolution process and cause Increased virulence may result in poor vaccine immunity or even immune failure
[0004] At present, in terms of treatment, the commonly used method is symptomatic treatment. For example, intramuscular injection of analgin, aminopyrine and other antipyretic and analgesic drugs combined with antibiotics to prevent secondary bacterial infection is often used for high fever symptoms caused by viral infection. It is only antipyretic, anti-inflammatory and analgesic, and has no antiviral effect. It can only be controlled temporarily, and it is easy to relapse. Although it can reduce the mortality rate to a certain extent, the growth performance of pigs is greatly affected, and the economic benefits are reduced.

Method used

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  • Antiviral compound traditional Chinese medicine preparation for pigs and preparation method of preparation
  • Antiviral compound traditional Chinese medicine preparation for pigs and preparation method of preparation
  • Antiviral compound traditional Chinese medicine preparation for pigs and preparation method of preparation

Examples

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preparation example Construction

[0024] The preparation method of antiviral compound traditional Chinese medicine preparation for pigs: after mixing mulberry leaves, ghost needle grass, licorice, gynostemma pentaphyllum, and soybean meal, add Bacillus subtilis, Bacillus licheniformis, lactic acid bacteria, yeast, neutral protease and acid protease, and mix well Add water to control the water content of the total material to 30-40%, then ferment at 35-38°C for 2-4 days, and post-ripen at room temperature for 7-15 days. After the fermentation is completed, the fermentation product is dried at low temperature until the water content is not higher than 13%. Antiviral compound Chinese medicine preparation for pigs.

[0025] The using method of the antiviral compound Chinese medicine preparation for pigs: directly mix the compound Chinese medicine preparation in the pig feed at a weight ratio of 0.5-2% of the pig feed.

Embodiment 1

[0027] A kind of antiviral compound traditional Chinese medicine preparation for pigs

[0028] 1) Raw materials: 2 parts of mulberry leaves, 5 parts of ghost needle grass, 1 part of licorice, 5 parts of gynostemma, 5 parts of soybean meal (the total weight of the above raw materials is recorded as A);

[0029] Bacillus subtilis (weight ratio to A is 1:2000)

[0030] Bacillus licheniformis (weight ratio to A is 1:5000)

[0031] Lactic acid bacteria (weight ratio to A is 1:2000)

[0032] Yeast (1:5000 by weight to A)

[0033] Neutral protease (weight ratio to A is 1:5000)

[0034] Acid protease (1:3000 by weight to A)

[0035] 2) Preparation method: After mixing mulberry leaves, ghost needle grass, licorice root, gynostemma pentaphyllum and soybean meal, add Bacillus subtilis, Bacillus licheniformis, lactic acid bacteria, yeast, neutral protease and acid protease, mix well, add water to control the total material content The water content is 30%, then fermented at 35°C for ...

Embodiment 2

[0037] A kind of antiviral compound traditional Chinese medicine preparation for pigs

[0038] 1) Raw materials: 5 parts of mulberry leaves, 2 parts of ghost needle grass, 2 parts of licorice, 1 part of Gynostemma pentaphyllum, 10 parts of soybean meal (the total weight of the above raw materials is recorded as A);

[0039] Bacillus subtilis (weight ratio to A is 1:5000)

[0040] Bacillus licheniformis (weight ratio to A is 1:2000)

[0041] Lactic acid bacteria (weight ratio to A is 1:5000)

[0042] Yeast (weight ratio to A is 1:2000)

[0043] Neutral protease (weight ratio to A is 1:10000)

[0044] Acid protease (1:3000 by weight to A)

[0045] 2) Preparation method: After mixing mulberry leaves, ghost needle grass, licorice root, gynostemma pentaphyllum and soybean meal, add Bacillus subtilis, Bacillus licheniformis, lactic acid bacteria, yeast, neutral protease and acid protease, mix well, add water to control the total material content The water content is 40%, then f...

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Abstract

The invention discloses an antiviral compound traditional Chinese medicine preparation for pigs and a preparation method of the preparation. The compound traditional Chinese medicine preparation is prepared from a traditional Chinese medicine composition, composite bacteria and composite enzyme, wherein the traditional Chinese medicine composition consists of 2-5 parts of mulberry leaf, 2-5 parts of spanishneedles herb, 1-2 parts of ural licorice root, 1-5 parts of fiveleaf gynostemma herb and 5-10 parts of soybean meal; the composite bacteria consists of bacillus subtilis, bacillus licheniformis, lactobacillus and yeast; and the composite enzyme consists of neutral protease and acidic protease. The method includes mixing the traditional Chinese medicine composition, the composite bacteria and the composite enzyme and fermenting to obtain the compound traditional Chinese medicine preparation. The traditional Chinese medicine preparation can reduce the infection and incidence rate of porcine viral diseases, control the mortality rate of infected pigs, improve the production performance of pigs and the immune effect of vaccines, reduce the diarrhea rate and the like by being added into the feed and fed to pigs.

Description

technical field [0001] The invention belongs to the technical field of antiviral diseases in breeding industry, and in particular relates to an antiviral compound traditional Chinese medicine preparation for pigs and a preparation method thereof. Background technique [0002] In the pig industry, when infected or invaded by viral diseases such as swine fever, porcine pseudorabies, porcine reproductive and respiratory syndrome, and porcine circus disease, it is easy to cause high mortality or even complete death of pigs. At present, it is mainly prevented and controlled by vaccine immunization. When the disease occurs, hyperimmune serum can be injected, and the mortality rate can be controlled by emergency immunization. The recovered or resistant pigs may be infected for life, and the growth and immune function will decline, losing economic value. [0003] In addition, hyperimmune serum is expensive, and the utilization rate of pig farms is not high. The control of these dise...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61P31/12
CPCA61K36/605A61K36/28A61K36/484A61K36/424A61K36/48A61P31/12A61K2236/19A61K2236/331A61K2300/00Y02P60/87
Inventor 邱龙新郭志军陈洪博杨剑陈敏
Owner LONGYAN UNIV