Cold-compress cold therapy gel and preparation method thereof

A gel and polyvinyl alcohol technology, applied in the biomedical field, can solve problems such as cross-infection, inconvenient fixation, and no antibacterial effect on the human body, so as to improve production efficiency, reduce production costs, good antibacterial properties and biocompatibility Effect

Inactive Publication Date: 2019-10-01
安徽深蓝医疗科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is inconvenient to fix when it is used, and it has no antibacterial effect on the human body, and it is easy to cause cross-infection, which is difficult to accept in hospital clinical practice.

Method used

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  • Cold-compress cold therapy gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] To prepare 100 grams of cold compress and cold therapy gel, the present invention can be obtained by the following method:

[0023] Step 1. Take 0.1 g of triclosan by weight, mix 3 g of sorbitol solution, add 10 ml of purified water, and mix well to obtain the desired disinfectant solution;

[0024] Step 2. Take 0.1 g of polyvinyl alcohol in parts by weight, swell the carbomer 0.1 with purified water, then add purified water to dilute, and then add the antibacterial solution prepared above;

[0025] Step 3. Add 5g of glycerin to the solution, continue to stir, adjust the PH value of 6-8 with 2g of triethanolamine, mix well, add purified water to make the volume to 100ml, and continue to stir to form a cold compress cold therapy gel 100 Grams.

Embodiment 2

[0027] To prepare 1000 grams of cold compress and cold therapy gel, the present invention can be obtained by the following method:

[0028] Step 1. Take 1g of triclosan in parts by weight, mix 30g of sorbitol solution, add 100ml of purified water, and mix evenly to obtain the required disinfectant solution;

[0029] Step 2. Take 1g of polyvinyl alcohol in parts by weight, swell 1g of carbomer with purified water, then add purified water to dilute, and then add the antibacterial solution prepared above;

[0030] Step 3. Add 50g of glycerin to the solution, continue to stir, adjust the pH to 6-8 with 20g of triethanolamine, mix well, add purified water to make the volume to 1000ml, continue to stir evenly, and form a cold compress cold therapy gel 1000 Grams.

Embodiment 3

[0032] To prepare 10,000 grams of cold compress and cold therapy gel, the present invention can be obtained by the following method:

[0033] Step 1. Take 10g of triclosan in parts by weight, mix 300g of sorbitol solution, add 1000ml of purified water, and mix evenly to obtain the required disinfectant solution;

[0034] Step 2. Take 10g of polyvinyl alcohol in parts by weight, swell 10g of carbomer with purified water, then add purified water to dilute, and then add the antibacterial liquid prepared above;

[0035] Step 3. Add 500g of glycerin to the solution, continue to stir, adjust the pH to 6-8 with 200g of triethanolamine, mix well, add purified water to make the volume to 10000ml, and continue to stir evenly to form a cold compress and cold therapy gel 10000 Grams.

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Abstract

The invention discloses a cold-compress cold therapy gel. The gel is prepared from 1-10 parts of polyvinyl alcohol, 1-10 parts of carbomer, 50-500 parts of glycerin, 2-20 parts of triethanolamine, 1-10 parts of triclosan, 30-300 parts of a sorbitol solution and the balance purified water, wherein the purified water is added until the total amount is 1,000-10,000, and uniform mixing is conducted toobtain the cold-compress cold therapy gel. The invention further discloses a preparation method of the cold-compress cold therapy gel. The prepared cold-compress cold therapy gel simultaneously combines the advantages of both triclosan and gel, has good antibacterial performance and biocompatibility, and can be used in the biomedical fields of diabetic skin infections, burns, scalds, acne infections, skin inflammations, gynecological diseases or anorectal diseases and the like. The antibacterial rate of the prepared cold-compress cold therapy gel is greater than or equal to 96% and is far higher than that of similar products; the cold-compress cold therapy gel has the advantages of being free of irritation, allergy or pollution, easy to remove and the like.

Description

Technical field [0001] The invention relates to a gel and a preparation method thereof, in particular to a cold compress cold therapy gel and a preparation method thereof, which are widely used in the field of biomedicine. Background technique [0002] Cold Therapy uses a medium below body temperature to contact the human body to cool it down, so as to achieve the purpose of curing diseases. The difference between it and cryotherapy is that the low temperature it adds to the human body will not cause tissue cell damage. Commonly used methods are ice water or ice pack local application, ice water bath or shower, and local refrigerant injection (such as ethyl chloride, liquid nitrogen, etc.). A few patients can also use intrabody infusion to lower their body temperature, such as children with high fever Use cold water enema. The most important therapeutic effect of local cold therapy is to relieve pain and reduce swelling. During cold stimulation, the nerve conduction speed slow...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K47/32A61K47/10A61K47/18A61K47/26A61K31/085A61P17/02A61P17/00A61P29/00A61P15/00A61P1/00A61P31/04
CPCA61K9/06A61K9/0014A61K47/32A61K47/10A61K47/18A61K47/26A61K31/085
Inventor 张超陈奉玲金国乐
Owner 安徽深蓝医疗科技股份有限公司
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