V-type coumarin fluorescent probe for hydrazine hydrate detection and preparation method thereof
A fluorescent probe, coumarin technology, applied in fluorescence/phosphorescence, chemical instruments and methods, luminescent materials, etc., can solve the problems of limited number of fluorescent probes, influence of interfering ions, complex probe synthesis, etc., to prevent interference , the effect of simple synthesis and low cost
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0028] (1) Dissolve 13 mmol of diethyl malonate and 5 mmol of salicylaldehyde in 20 mL of ethanol, add dropwise two drops of glacial acetic acid and 0.1 mL of piperidine, and stir under reflux for 6 h at room temperature; add ice water after the reaction is complete A precipitate was precipitated, filtered and washed with ice water to obtain ethyl coumarin-3-carboxylate as a white solid;
[0029] (2) Mix 5 mmol of ethyl coumarin-3-carboxylate and 2.5 mmol of resorcinol, add 0.02 g of DMAP, and 2 Heated to 140°C under protection, reacted for 3 h, added ethanol and sonicated for 10 min, filtered and rinsed with ethanol to obtain V-type coumarin in the form of orange-yellow solid;
[0030] (3) Mix and dissolve 5 mmol V-type coumarin and 7 mmol 4-fluorobutyric acid in 20 mL of dichloromethane, add 0.02 g DMAP and 0.2 g DCC, stir at room temperature for 4 h, and distill off the solvent under reduced pressure The crude probe was obtained and purified by column chromatography with d...
Embodiment 2
[0032] (1) Dissolve 13 mmol of diethyl malonate and 5 mmol of salicylaldehyde in 20 mL of ethanol, add dropwise two drops of glacial acetic acid and 0.1 mL of piperidine, and stir at room temperature for 8 h under reflux; after the reaction is complete, add ice water A precipitate was precipitated, filtered and washed with ice water to obtain ethyl coumarin-3-carboxylate as a white solid;
[0033] (2) Mix 5 mmol of ethyl coumarin-3-carboxylate and 2.5 mmol of resorcinol, add 0.02 g of DMAP, and 2 Heated to 140°C under protection, reacted for 4 h, added ethanol and sonicated for 15 min, filtered and rinsed with ethanol to obtain V-type coumarin in the form of orange-yellow solid;
[0034] (3) Mix and dissolve 5 mmol V-type coumarin and 7 mmol 4-chlorobutyric acid in 20 mL of dichloromethane, add 0.02 g DMAP and 0.2 g DCC, stir at room temperature for 6 h, and distill off the solvent under reduced pressure The crude probe was obtained and purified by column chromatography with ...
Embodiment 3
[0036] (1) Dissolve 13 mmol of diethyl malonate and 5 mmol of salicylaldehyde in 20 mL of ethanol, add dropwise two drops of glacial acetic acid and 0.1 mL of piperidine, and stir under reflux for 6 h at room temperature; add ice water after the reaction is complete A precipitate was precipitated, filtered and washed with ice water to obtain ethyl coumarin-3-carboxylate as a white solid;
[0037] (2) Mix 5 mmol of ethyl coumarin-3-carboxylate and 2.5 mmol of resorcinol, add 0.1 g of AlCl 3 , at N 2 Heated to 140°C under protection, reacted for 3 h, added ethanol and sonicated for 10 min, filtered and rinsed with ethanol to obtain V-type coumarin in the form of orange-yellow solid;
[0038] (3) Mix and dissolve 5 mmol V-type coumarin and 7 mmol 4-chlorobutyric acid in 20 mL of dichloromethane, add 0.02 g DMAP and 0.2 g DCC, stir at room temperature for 5 h, and distill off the solvent under reduced pressure The crude probe was obtained and purified by column chromatography wi...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More