Vaginal expansion suppository containing lactobacillus and lactose and preparation method thereof

Abstract

The invention provides a vaginal expansion suppository containing lactobacillus and lactose and a preparation method thereof. The vaginal expansion suppository comprises an expansion carrier and a drug-containing matrix coating the surface of the expansion carrier; the drug-containing matrix comprises lactobacillus, lactose and a matrix; and the synergistic cooperation between the lactobacillus and the lactose promotes the growth and proliferation of effective microbial communities in the vagina, and inhibits and eliminates pathogenic bacteria in a broad-spectrum manner, so that the vagina microbial community environment is thoroughly improved, and the micro-ecological health in the vagina is maintained. By combining effective medicine ingredients with the expansion carrier, the vaginal expansion suppository provided by the invention promotes full contact between the suppository and a focus part and the absorption of the focus part to medicines, so that the vaginal expansion suppository is high in stability, stable and lasting in curative effect, good in treatment effect and high in effective rate of treating bacterial vaginitis and candida vaginitis, and the recurrence rate afterone year of healing is lower than 15%.

Description

technical field [0001] The invention belongs to the technical field of vaginal suppositories, in particular to a vaginal expansive suppository containing lactobacillus and lactose and a preparation method thereof. Background technique [0002] Studies have shown that under normal circumstances, dozens of microorganisms can be isolated from the female vagina, including Candida albicans, Gardnerella, Escherichia coli, Enterococcus, Peptostreptococcus, Staphylococcus epidermidis and other opportunistic pathogens. At the same time, probiotics such as bifidobacteria and lactobacilli can also be isolated, and the pathogenic bacteria and probiotics are in a state of dynamic balance. When this balance is broken, it will cause a variety of diseases such as bacterial vaginosis, aerobic bacterial vaginosis and so on. Bacterial vaginosis can cause a variety of diseases, such as chronic cervicitis, cervical cancer, ovarian cancer, fallopian tube tumors and other diseases; it is also the...

AI Technical Summary

Problems solved by technology

Although antibiotics have a positive effect on disease control, antibiotic treatment only reduces inflammation, but does not restore the normal vaginal microbial environment, so it is easy to relapse after recovery; in addition, the widespread and irrational use of antibacterial drugs has led to the resistance of some pathogenic bacteria to drugs , making bacteria less sensitive to drugs and increasing the risk of superbugs

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